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This study aimed to investigate electrical pulp test thresholds in MS patients without a history of trigeminal neuralgia compared to healthy individuals.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Sixty-nine maxillary central incisors, belonging to 34 relapsing-remitting MS patients, and 35 healthy individuals were included in this survey. The MS patients matched for intended variables, were 22\u201350\u2009years old, had a more than 1-year history of MS, no history of trigeminal neuralgia and\/or other neuropathy. The electric pulp sensibility test was performed on all samples. Electric pulp testing (EPT) results were recorded based on the pulp tester<jats:sup>\u2019<\/jats:sup>s grade that evoked a response. Data were analyzed with paired T-test, Mann-Whitney test, and Spearman correlation (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>According to the results of this study, the mean values of response to EPT were 1.2\u2009\u00b1\u20090.5 and 1.8\u2009\u00b1\u20090.5 in MS patients and healthy individuals, respectively. The pulpal response to EPT between the two groups was significantly different (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>MS patients showed a significantly reduced response to the electric pulp test in their maxillary central incisors in comparison to matched healthy persons.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12883-021-02416-0","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T08:17:20Z","timestamp":1634717840000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of the response to electric pulp testing in multiple sclerosis patients without a history of trigeminal neuralgia: a case-control study"],"prefix":"10.1186","volume":"21","author":[{"given":"Fatemeh","family":"Owlia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazanin","family":"Mahmoudzade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalil","family":"Modaresi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzieh Abutorabi","family":"Zarchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,20]]},"reference":[{"issue":"9","key":"2416_CR1","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1002\/acn3.50862","volume":"6","author":"E Waubant","year":"2019","unstructured":"Waubant E, Lucas R, Mowry E, Graves J, Olsson T, Alfredsson L, et al. 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The study conformed to the Declaration of Helsinki guidelines and was approved by the ethics committee of Yazd Shahid Sadoughi University of medical science, Yazd, Iran (ref no: IR.SSU.REC.1396.194). All methods were performed in accordance with the relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Authors mention that there is no conflict of interest in this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"403"}}