{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T19:30:06Z","timestamp":1783971006077,"version":"3.55.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>\nSudden onset of severe headache is the most common presentation of a ruptured intracranial aneurysm. Similar symptoms can be caused by pituitary apoplexy, and radiological examination is needed to distinguish between the two. Development of infarction and\/or haemorrhage of the hypophysis with concomitant unruptured cerebral aneurysm has been described. However, intratumoural aneurysm within a pituitary adenoma presenting with the ictus of both pathologies is extremely rare.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 64-year-old man presented with classic symptoms of pituitary apoplexy. His symptoms improved after a few days, and he was discharged. However, he subsequently developed further episodes of sudden and severe headache together with visual decline and ophthalmoplegia. Radiographs demonstrated an enlarging sellar mass with suspicion of a ruptured internal carotid artery aneurysm, within the apoplectic pituitary macroadenoma. Although an endovascular procedure was planned, the patient developed massive subarachnoid haemorrhage resulting in brain death.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This case report describes an intratumoural aneurysm of the cavernous internal carotid artery as a potential cause or result of pituitary apoplexy. Despite its rarity, this possible life-threatening complication of pituitary apoplexy should be recognised for prompt diagnosis and early management.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12883-022-02999-2","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T05:03:05Z","timestamp":1670562185000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Double jeopardy - pituitary apoplexy complicated by ruptured aneurysm of the internal carotid artery within an adenoma: a case report"],"prefix":"10.1186","volume":"22","author":[{"given":"Nutnicha","family":"Pattaravimonporn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wasawat","family":"Muninthorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanwa","family":"Sudsang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ake","family":"Hansasuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dararat","family":"Chiewchalermsri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8294-8601","authenticated-orcid":false,"given":"Chutintorn","family":"Sriphrapradang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"issue":"6","key":"2999_CR1","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1210\/er.2015-1042","volume":"36","author":"C Briet","year":"2015","unstructured":"Briet C, Salenave S, Bonneville JF, Laws ER, Chanson P. Pituitary Apoplexy. Endocr Rev. 2015;36(6):622\u201345.","journal-title":"Endocr Rev"},{"issue":"2","key":"2999_CR2","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1161\/01.STR.32.2.567","volume":"32","author":"H Suzuki","year":"2001","unstructured":"Suzuki H, Muramatsu M, Murao K, Kawaguchi K, Shimizu T. Pituitary apoplexy caused by ruptured internal carotid artery aneurysm. Stroke. 2001;32(2):567\u20139.","journal-title":"Stroke"},{"key":"2999_CR3","doi-asserted-by":"crossref","unstructured":"Krug RG, 2nd, Chang AY,\nRaghunathan A, Van Gompel JJ. Apoplectic Silent Crooke Cell Adenoma with Adjacent\nPseudoaneurysms: Causation or Bystander? World Neurosurg. 2019;122:480-4.","DOI":"10.1016\/j.wneu.2018.10.232"},{"issue":"26","key":"2999_CR4","doi-asserted-by":"publisher","first-page":"CASE21169","DOI":"10.3171\/CASE21169","volume":"1","author":"M Yoshida","year":"2021","unstructured":"Yoshida M, Hiu T, Baba S, Morikawa M, Horie N, Ujifuku K, et al. Ruptured aneurysm\u2013induced pituitary apoplexy: illustrative case. J Neurosurg Case Lessons. 2021;1(26):CASE21169.","journal-title":"J Neurosurg Case Lessons"},{"issue":"5","key":"2999_CR5","doi-asserted-by":"publisher","first-page":"942","DOI":"10.3171\/2011.12.JNS11875","volume":"116","author":"MC Oh","year":"2012","unstructured":"Oh MC, Kim EH, Kim SH. Coexistence of intracranial aneurysm in 800 patients with surgically confirmed pituitary adenoma. J Neurosurg. 2012;116(5):942\u20137.","journal-title":"J Neurosurg"},{"key":"2999_CR6","doi-asserted-by":"publisher","first-page":"e526-e33","DOI":"10.1016\/j.wneu.2019.02.084","volume":"126","author":"J Hu","year":"2019","unstructured":"Hu J, Lin Z, Zhang Y, Zheng X, Ran Q, Zhang D, et al. Prevalence of Unruptured Intracranial Aneurysms coexisting with Pituitary Adenomas. World Neurosurg. 2019;126:e526-e33.","journal-title":"World Neurosurg"},{"issue":"3","key":"2999_CR7","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1055\/s-0041-1735904","volume":"82","author":"KJ Piper","year":"2021","unstructured":"Piper KJ, Karsy M, Barton B, Rabinowitz M, Rosen MR, Nyquist GG, et al. Management of Coincident Pituitary Macroadenoma and cavernous carotid aneurysm: a systematic literature review. J Neurol Surg Rep. 2021;82(3):e25\u201331.","journal-title":"J Neurol Surg Rep"},{"issue":"1","key":"2999_CR8","doi-asserted-by":"publisher","first-page":"e4","DOI":"10.3171\/foc.2000.8.1.1829","volume":"8","author":"PS Larson","year":"2000","unstructured":"Larson PS, Reisner A, Morassutti DJ, Abdulhadi B, Harpring JE. Traumatic intracranial aneurysms. Neurosurg Focus. 2000;8(1):e4.","journal-title":"Neurosurg Focus"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-022-02999-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12883-022-02999-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-022-02999-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T05:03:31Z","timestamp":1670562211000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcneurol.biomedcentral.com\/articles\/10.1186\/s12883-022-02999-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,9]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["2999"],"URL":"https:\/\/doi.org\/10.1186\/s12883-022-02999-2","relation":{},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,9]]},"assertion":[{"value":"29 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This case report was approved by the Human Research Ethics Committee of the Faculty of Medicine Ramathibodi Hospital, Mahidol University (Ethic approval number: MURA2022\/271).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval\u00a0and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s next-of-kin for publication of this case report and images. A copy of this written consent is available for review.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"463"}}