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This study aims to explore the potential correlation between alcohol consumption and cerebral stenosis in patients with acute ischemic stroke and transient ischemic attack (TIA).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Nine hundreds and eighty-eight patients with first acute ischemic stroke attack or TIA were recruited retrospectively. Alcohol consumption was classified into five consumption categories (non-drinkers, occasional drinkers, &lt;\u2009140\u00a0g per week [mild drinkers], 140\u2013279\u00a0g per week [moderate drinkers], \u2265\u2009280\u00a0g per week [heavy drinkers]). Computed tomography angiography (CTA) and digital subtraction angiography (DSA) were utilized to assess the carotid and cerebral artery in all patients. Five-step scale for degree of stenosis was applied: normal (0, 0 points), mild (&lt;\u200950%, 1 point), moderate (50\u201369%, 2 points), severe (70\u201399%, 3 points), and occlusion (100%, 4 points).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The carotid and cerebral artery stenosis scores were positively correlated with moderate alcohol consumption (B\u2009=\u20091.695, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Compared with nondrinkers, moderate alcohol consumption had significant increasing risk of moderate carotid and cerebral artery stenosis (OR\u2009=\u20094.28, 95% CI: 1.47\u201312.49, <jats:italic>P<\/jats:italic>\u2009=\u20090.008) and severe stenosis (OR\u2009=\u20094.24, 95% CI: 1.55\u201311.64, <jats:italic>P<\/jats:italic>\u2009=\u20090.005) and occlusion (OR\u2009=\u20093.87, 95% CI: 1.65\u20139.06, <jats:italic>P<\/jats:italic>\u2009=\u20090.002). Compared with nondrinkers, heavy alcohol consumption patients had significant higher risk of carotid and cerebral artery occlusion (OR\u2009=\u20092.71, 95% CI: 1.36\u20135.41, <jats:italic>P<\/jats:italic>\u2009=\u20090.005).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Higher alcohol consumption may associate with higher risk and more severity of carotid and cerebrovascular stenosis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12883-024-03627-x","type":"journal-article","created":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T04:01:43Z","timestamp":1713844903000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Alcohol consumption may be a risk factor for cerebrovascular stenosis in acute ischemic stroke and transient ischemic attack"],"prefix":"10.1186","volume":"24","author":[{"given":"Yiti","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maoyuan","family":"Gou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,23]]},"reference":[{"key":"3627_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(21)00252-0","author":"regional Global","year":"2021","unstructured":"Global regional. 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