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Conventional PD detection algorithms are generally based on first and second-generation artificial neural network (ANN) models which consume high energy and have complex architecture. Considering these limitations, a time-varying synaptic efficacy function\u00a0based leaky-integrate and fire neuron model, called SEFRON is used for the detection of PD. SEFRON explores the advantages of Spiking Neural Network (SNN) which is suitable for neuromorphic devices. To evaluate the performance of SEFRON, 2 publicly available standard datasets, namely (1) UCI: Oxford Parkinson\u2019s Disease Detection Dataset and (2) UCI: Parkinson Dataset with replicated acoustic features are used. The performance is compared with other well-known neural network models: Multilayer Perceptron Neural Network (MLP-NN), Radial Basis Function Neural Network (RBF-NN), Recurrent Neural Network (RNN) and Long short-term memory (LSTM). The experimental results demonstrate that the SEFRON classifier achieves a maximum accuracy of 100% and an average accuracy of 99.49% on dataset 1. For dataset 2, it attains a peak accuracy of 94% and an average accuracy of 91.94%, outperforming the other classifiers in both cases. From the performance, it is proved that the presented model can help to develop a robust automated PD detection device that can assist the physicians to diagnose the disease at its early stage.<\/jats:p>","DOI":"10.1186\/s12883-024-04001-7","type":"journal-article","created":{"date-parts":[[2024,12,29]],"date-time":"2024-12-29T22:21:25Z","timestamp":1735510885000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A robust Parkinson\u2019s disease detection model based on time-varying synaptic efficacy function in spiking neural network"],"prefix":"10.1186","volume":"24","author":[{"given":"Priya","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarita","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganapati","family":"Panda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata","family":"Dash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amel","family":"Ksibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrooq","family":"Alsenan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wided","family":"Bouchelligua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurav","family":"Mallik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,30]]},"reference":[{"key":"4001_CR1","unstructured":"Parkinson\u2019s Disease. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/parkinson-disease. 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