{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T23:24:22Z","timestamp":1787268262423,"version":"build-2736575974"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":70,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to compare the image quality of 5.0T and 3.0T time-of-flight (TOF) magnetic resonance angiography (MRA) for visualization of the anterior choroidal artery (AChA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included patients who underwent both 3.0T and 5.0T TOF-MRA within a 48-hour interval. Objective image quality was assessed using signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Subjective image quality was independently evaluated by two radiologists using segment-based AChA visibility scores, and quantitative measurements of vessel length and diameter were obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 42 patients who underwent both 3.0T and 5.0T TOF-MRA were included in the paired analysis. Compared with 3.0T imaging, 5.0T TOF-MRA demonstrated significantly higher objective image quality, with increased signal-to-noise ratio (93\u2009\u00b1\u20095 vs. 65\u2009\u00b1\u20093) and contrast-to-noise ratio (75\u2009\u00b1\u20096 vs. 52\u2009\u00b1\u20094) (both\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Subjective analysis showed significantly higher visibility scores for distal anterior choroidal artery segments on 5.0T imaging, particularly for the A2 (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.007) and A3 (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) segments. Paired morphological measurements further demonstrated greater apparent AChA length (left: 24.4\u2009\u00b1\u20097.3\u00a0mm vs. 18.7\u2009\u00b1\u20099.2\u00a0mm;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and diameter (left: 1.1\u00a0mm (1.0-1.2) vs. 0.9\u00a0mm (0.7\u20131.1);\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) on 5.0T TOF-MRA compared with 3.0T imaging.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>5.0T TOF-MRA improved visualization of the AChA, particularly its distal segments, compared with 3.0T imaging; further studies are needed to clarify its clinical implications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial number<\/jats:title>\n                    <jats:p>Not applicable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12883-026-05019-9","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T03:45:49Z","timestamp":1781235949000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of 5.0T and 3.0T time-of-flight MR angiography for visualizing the anterior choroidal artery"],"prefix":"10.1186","volume":"26","author":[{"given":"Zhangzhu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyan","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhensong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"5019_CR1","unstructured":"Javed K, Das JM, Neuroanatomy. Anterior Choroidal Arteries. StatPearls. Treasure Island (FL) ineligible companies. Disclosure: Joe Das declares no relevant financial relationships with ineligible companies.: StatPearls Publishing Copyright \u00a9 2025. StatPearls Publishing LLC.; 2025."},{"key":"5019_CR2","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1159\/000515574","volume":"13","author":"S Narayana Patro","year":"2021","unstructured":"Narayana Patro S, Hassan Haroon K, Tamboli K, Zafar A, Hussain S, Muhammad A. A Case of Anterior Choroidal Artery Occlusion and Stroke Secondary to External Compression. Case Rep Neurol. 2021;13:369\u201374.","journal-title":"Case Rep Neurol"},{"key":"5019_CR3","doi-asserted-by":"crossref","unstructured":"Tsika A, Stamati P, Tsouris Z, Provatas A, Papa A, Tsimoulis D, et al. Acute Anterior Choroidal Artery Territory Infarction: Case Ser Rep. 2024;16:289\u201398.","DOI":"10.3390\/neurolint16020020"},{"key":"5019_CR4","doi-asserted-by":"publisher","unstructured":"Nadaf S, Chakor RT, Kothari KV, Patel BA. Anterior choroidal artery infarction. BMJ Case Rep. 2018;2018:bcr2017222414. https:\/\/doi.org\/10.1136\/bcr-2017-222414.","DOI":"10.1136\/bcr-2017-222414"},{"key":"5019_CR5","doi-asserted-by":"publisher","first-page":"368","DOI":"10.7150\/ijms.22631","volume":"15","author":"J Yu","year":"2018","unstructured":"Yu J, Xu N, Zhao Y, Yu J. Clinical importance of the anterior choroidal artery: a review of the literature. Int J Med Sci. 2018;15:368\u201375.","journal-title":"Int J Med Sci"},{"key":"5019_CR6","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/s12880-022-00790-w","volume":"22","author":"S Ren","year":"2022","unstructured":"Ren S, Wu W, Su C, Zhu Q, Schmidt M, Sun Y, et al. High-resolution compressed sensing time-of-flight MR angiography outperforms CT angiography for evaluating patients with Moyamoya disease after surgical revascularization. BMC Med Imaging. 2022;22:64.","journal-title":"BMC Med Imaging"},{"key":"5019_CR7","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s41747-024-00463-z","volume":"8","author":"M Cosottini","year":"2024","unstructured":"Cosottini M, Calzoni T, Lazzarotti GA, Grigolini A, Bosco P, Cecchi P, et al. Time-of-flight MRA of intracranial vessels at 7 T. Eur Radiol Experimental. 2024;8:68.","journal-title":"Eur Radiol Experimental"},{"key":"5019_CR8","first-page":"305","volume":"22","author":"M Wiesmann","year":"2001","unstructured":"Wiesmann M, Yousry I, Seelos KC, Yousry TA. Identification and anatomic description of the anterior choroidal artery by use of 3D-TOF source and 3D-CISS MR imaging. AJNR Am J Neuroradiol. 2001;22:305\u201310.","journal-title":"AJNR Am J Neuroradiol"},{"key":"5019_CR9","doi-asserted-by":"publisher","first-page":"e1072","DOI":"10.1016\/j.wneu.2024.05.050","volume":"187","author":"J Park","year":"2024","unstructured":"Park J, Son W, Kim M, Shin IH. Anterior Choroidal Artery Aneurysm Clipping: Angiographic Diagnostics and Surgical Tactics Focused on Visualizing the Anterior Choroidal Artery Behind the Aneurysm. World Neurosurg. 2024;187:e1072\u201382.","journal-title":"World Neurosurg"},{"key":"5019_CR10","first-page":"1438","volume":"15","author":"SS Mooldijk","year":"2024","unstructured":"Mooldijk SS, Ikram MA. Cerebral Small Vessel Disease in Population-Based Research: What are We Looking at - and What not? Aging Dis. 2024;15:1438\u201346.","journal-title":"Aging Dis"},{"key":"5019_CR11","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1002\/nbm.3306","volume":"29","author":"WH Bouvy","year":"2016","unstructured":"Bouvy WH, Geurts LJ, Kuijf HJ, Luijten PR, Kappelle LJ, Biessels GJ, et al. Assessment of blood flow velocity and pulsatility in cerebral perforating arteries with 7-T quantitative flow MRI. NMR Biomed. 2016;29:1295\u2013304.","journal-title":"NMR Biomed"},{"key":"5019_CR12","first-page":"822","volume":"27","author":"TA Cashen","year":"2006","unstructured":"Cashen TA, Carr JC, Shin W, Walker MT, Futterer SF, Shaibani A, et al. Intracranial time-resolved contrast-enhanced MR angiography at 3T. AJNR Am J Neuroradiol. 2006;27:822\u20139.","journal-title":"AJNR Am J Neuroradiol"},{"key":"5019_CR13","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3174\/ajnr.A6344","volume":"41","author":"JW Rutland","year":"2020","unstructured":"Rutland JW, Delman BN, Gill CM, Zhu C, Shrivastava RK, Balchandani P. Emerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future Directions. AJNR Am J Neuroradiol. 2020;41:2\u20139.","journal-title":"AJNR Am J Neuroradiol"},{"key":"5019_CR14","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.neuroimage.2017.01.019","volume":"168","author":"CA Park","year":"2018","unstructured":"Park CA, Kang CK, Kim YB, Cho ZH. Advances in MR angiography with 7T MRI: From microvascular imaging to functional angiography. NeuroImage. 2018;168:269\u201378.","journal-title":"NeuroImage"},{"key":"5019_CR15","doi-asserted-by":"crossref","unstructured":"Lakhani DA, Zhou X, Tao S, Middlebrooks EH. Increased Resolution of Time-of-Flight MR Angiography at Higher Field Strength. Radiology. 2023;307:e222619.","DOI":"10.1148\/radiol.222619"},{"key":"5019_CR16","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1148\/radiol.220114","volume":"306","author":"Z Shi","year":"2023","unstructured":"Shi Z, Zhao X, Zhu S, Miao X, Zhang Y, Han S, et al. Time-of-Flight Intracranial MRA at 3 T versus 5 T versus 7 T: Visualization of Distal Small Cerebral Arteries. Radiology. 2023;306:207\u201317.","journal-title":"Radiology"},{"key":"5019_CR17","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.21037\/qims-24-1554","volume":"15","author":"H Mei","year":"2025","unstructured":"Mei H, Lv J, Xu D, Gao L, Sun W, Zhong X, et al. 3D time-of-flight magnetic resonance angiography of lenticulostriate artery imaging at 5.0 Tesla: a hierarchic analysis method and clinical applications. Quant Imaging Med Surg. 2025;15:1768\u201383.","journal-title":"Quant Imaging Med Surg"},{"key":"5019_CR18","doi-asserted-by":"publisher","first-page":"101830","DOI":"10.1016\/j.compmedimag.2020.101830","volume":"89","author":"J Liu","year":"2021","unstructured":"Liu J, Chen F, Wang X, Zhang X, Sun K, Xue R, et al. A comparative analysis framework of 3T and 7T TOF-MRA based on automated cerebrovascular segmentation. Comput Med Imaging Graph. 2021;89:101830.","journal-title":"Comput Med Imaging Graph"},{"key":"5019_CR19","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1002\/mrm.27769","volume":"82","author":"C Wink","year":"2019","unstructured":"Wink C, Ferrazzi G, Bassenge JP, Flassbeck S, Schmidt S, Schaeffter T, et al. 4D flow imaging with 2D-selective excitation. Magn Reson Med. 2019;82:886\u2013900.","journal-title":"Magn Reson Med"},{"key":"5019_CR20","doi-asserted-by":"publisher","first-page":"e0241779","DOI":"10.1371\/journal.pone.0241779","volume":"15","author":"MJ Willemink","year":"2020","unstructured":"Willemink MJ, Coolen BF, Dyvorne H, Robson PM, Bander I, Ishino S, et al. Ultra-high resolution, 3-dimensional magnetic resonance imaging of the atherosclerotic vessel wall at clinical 7T. PLoS ONE. 2020;15:e0241779.","journal-title":"PLoS ONE"},{"key":"5019_CR21","doi-asserted-by":"publisher","first-page":"2384","DOI":"10.1007\/s00330-021-08331-9","volume":"32","author":"J Feng","year":"2022","unstructured":"Feng J, Liu X, Zhang Z, Wu Y, Li Z, Zhang Q, et al. Comparison of 7 T and 3 T vessel wall MRI for the evaluation of intracranial aneurysm wall. Eur Radiol. 2022;32:2384\u201392.","journal-title":"Eur Radiol"},{"key":"5019_CR22","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s10143-022-01933-x","volume":"46","author":"T Matsushige","year":"2022","unstructured":"Matsushige T, Hashimoto Y, Ogawa T, Makimoto G, Yoshiyama M, Hara T, et al. The impact of high-resolution cone-beam CT findings on decision-making for the treatment of unruptured middle cerebral artery aneurysms. Neurosurg Rev. 2022;46:26.","journal-title":"Neurosurg Rev"},{"key":"5019_CR23","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1177\/1591019917706190","volume":"23","author":"K Shimada","year":"2017","unstructured":"Shimada K, Tanaka M, Kadooka K, Hadeishi H. Efficacy of high-resolution cone-beam CT in the evaluation of perforators in vertebral artery dissection. Interv Neuroradiol. 2017;23:350\u201356.","journal-title":"Interv Neuroradiol"},{"key":"5019_CR24","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3171\/2024.4.JNS24362","volume":"142","author":"P Barhouse","year":"2025","unstructured":"Barhouse P, Young M, Taussky P, Pacheco-Barrios N, Ogilvy CS. Anterior choroidal artery aneurysms: a systematic review and meta-analysis of outcomes and ischemic complications following surgical and endovascular treatment. J Neurosurg. 2025;142:127\u201337.","journal-title":"J Neurosurg"},{"key":"5019_CR25","doi-asserted-by":"publisher","first-page":"e157","DOI":"10.1016\/j.wneu.2022.07.111","volume":"167","author":"T Maeda","year":"2022","unstructured":"Maeda T, Ooigawa H, Suzuki K, Sato H, Iihoshi S, Kohyama S, et al. Predictors of Ischemic Complication in Anterior Choroidal Artery Aneurysm Repair. World Neurosurg. 2022;167:e157\u201364.","journal-title":"World Neurosurg"},{"key":"5019_CR26","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1136\/jnis-2023-020668","volume":"16","author":"B Sui","year":"2024","unstructured":"Sui B, Sannananja B, Zhu C, Balu N, Eisenmenger L, Baradaran H, et al. Report from the society of magnetic resonance angiography: clinical applications of 7T neurovascular MR in the assessment of intracranial vascular disease. J Neurointerv Surg. 2024;16:846\u201351.","journal-title":"J Neurointerv Surg"},{"key":"5019_CR27","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1038\/s41597-024-03397-8","volume":"11","author":"CM de Nys","year":"2024","unstructured":"de Nys CM, Liang ES, Prior M, Woodruff MA, Novak JI, Murphy AR, et al. Time-of-Flight MRA of Intracranial Aneurysms with Interval Surveillance, Clinical Segmentation and Annotations. Sci Data. 2024;11:555.","journal-title":"Sci Data"},{"key":"5019_CR28","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.3174\/ajnr.A2093","volume":"31","author":"H Raoult","year":"2010","unstructured":"Raoult H, Ferr\u00e9 JC, Morandi X, Carsin-Nicol B, Carsin M, Cuggia M, et al. Quality-evaluation scheme for cerebral time-resolved 3D contrast-enhanced MR angiography techniques. AJNR Am J Neuroradiol. 2010;31:1480\u20137.","journal-title":"AJNR Am J Neuroradiol"},{"key":"5019_CR29","doi-asserted-by":"publisher","first-page":"118033","DOI":"10.1016\/j.neuroimage.2021.118033","volume":"236","author":"AC Carpenter","year":"2021","unstructured":"Carpenter AC, Thakral PP, Preston AR, Schacter DL. Reinstatement of item-specific contextual details during retrieval supports recombination-related false memories. NeuroImage. 2021;236:118033.","journal-title":"NeuroImage"},{"key":"5019_CR30","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1136\/annrheumdis-2021-eular.1417","volume":"80","author":"D Krijbolder","year":"2021","unstructured":"Krijbolder D, Verstappen M, Wouters F, Lard LR, Buck PDD, Dieren JV-v, et al. POS1391\u2005measuring subclinical inflammation in hand and forefoot in patients with arthralgia using 1.5T OR 3.0T MRI: does field strength matter? Ann Rheumatic Dis. 2021;80:978.","journal-title":"Ann Rheumatic Dis"},{"key":"5019_CR31","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.ejrad.2013.09.018","volume":"83","author":"S Clasen","year":"2014","unstructured":"Clasen S, Rempp H, Hoffmann R, Graf H, Pereira PL, Claussen CD. Image-guided radiofrequency ablation of hepatocellular carcinoma (HCC): is MR guidance more effective than CT guidance? Eur J Radiol. 2014;83:111\u20136.","journal-title":"Eur J Radiol"},{"key":"5019_CR32","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s00234-022-03093-7","volume":"65","author":"O Tritanon","year":"2023","unstructured":"Tritanon O, Mataeng S, Apirakkan M, Panyaping T. Utility of high-resolution magnetic resonance vessel wall imaging in differentiating between atherosclerotic plaques, vasculitis, and arterial dissection. Neuroradiology. 2023;65:441\u201351.","journal-title":"Neuroradiology"},{"key":"5019_CR33","doi-asserted-by":"publisher","first-page":"573","DOI":"10.5692\/clinicalneurol.cn-001447","volume":"60","author":"S Inui","year":"2020","unstructured":"Inui S, Yamamoto A, Sakurai K. [Imaging diagnosis of intracranial artery dissections: visualization of the vessel walls on high-resolution vessel wall imaging]. Rinsho Shinkeigaku. 2020;60:573\u201380.","journal-title":"Rinsho Shinkeigaku"},{"key":"5019_CR34","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.21037\/qims-22-945","volume":"13","author":"Z Wei","year":"2023","unstructured":"Wei Z, Chen Q, Han S, Zhang S, Zhang N, Zhang L, et al. 5T magnetic resonance imaging: radio frequency hardware and initial brain imaging. Quant Imaging Med Surg. 2023;13:3222\u201340.","journal-title":"Quant Imaging Med Surg"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12883-026-05019-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-026-05019-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-026-05019-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T22:42:10Z","timestamp":1787265730000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12883-026-05019-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,12]]},"references-count":34,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5019"],"URL":"https:\/\/doi.org\/10.1186\/s12883-026-05019-9","relation":{},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,12]]},"assertion":[{"value":"17 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the Institutional Review Board of Medical Ethics Committee of Shandong Provincial Third Hospital (KYLL-2023077). and the requirement for informed consent was waived by the Institutional Review Board of Shandong Provincial Third Hospital because of the retrospective nature of the study. I confirm that all methods were performed in accordance with the relevant guidelines. All procedures were performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was released with the consent of the patients.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"529"}}