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This study was approved by the Ethics Committee of IRCCS Fondazione Ca\u2019 Granda Ospedale Maggiore Policlinico, Italy, with approval number 186771.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"521"}}