{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:43:05Z","timestamp":1789155785250,"version":"build-2803163510"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T00:00:00Z","timestamp":1576454400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pregnancy Childbirth"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The aim of this study was to assess the feasibility, safety and outcome of the embolization of non-gonadal collateral supplying gestational sac (GS) in addition to uterine artery embolization (UAE), followed by hysteroscopic curettage for the management of cesarean scar pregnancy (CSP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was undertaken from January 2012 to September 2018 in 24 CSP patients in whom non-gonadal collaterals supplying GS were identified by arterial angiography performed immediately after UAE. These patients underwent attempt collateral embolization in addition to UAE, followed by hysteroscopic curettage for the management of CSP. The 24 patients were divided into two groups based on whether they underwent technically successful collateral embolization (UAE-SCE group) or failed collateral embolization (UAE-FCE group) in addition to UAE. The baseline characteristics and clinical outcomes including time for serum \u03b2-human chorionic gonadotropin (\u03b2-hCG) levels normalization, blood loss, secondary anemia, and pelvic pain were compared between the two groups. The paired t test and Man Whitney test were used for comparisons of discrete and numerical variables, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Collateral embolization was techinically successful in 16 (66.7%, 16\/24) patients and failed in the other 8 (33.3%, 8\/24) patients. There were no significant differences between the two groups in baseline characteristics. The mean blood loss and secondary anemia in the UAE-SCE group were significantly less than UAE-FCE group. No significant difference was found between the two groups in the mean time for \u03b2-hCG levels normalization and pelvic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>During the management of UAE combined with hysteroscopic curettage for CSP, additional embolization of non-gonadal collateral supplying GS during UAE is feasible and safe in patients with non-gonadal collateral supplying GS, and the additional embolization of the collateral may reduce blood bloss related to hysteroscopic curettage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12884-019-2590-2","type":"journal-article","created":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T13:03:00Z","timestamp":1576501380000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Role of collateral embolization in addition to uterine artery embolization followed by hysteroscopic curettage for the management of cesarean scar pregnancy"],"prefix":"10.1186","volume":"19","author":[{"given":"Guodong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jijun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dechao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7124-9522","authenticated-orcid":false,"given":"Zengtao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,16]]},"reference":[{"issue":"6","key":"2590_CR1","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1097\/01.AOG.0000218690.24494.ce","volume":"107","author":"MA Rotas","year":"2006","unstructured":"Rotas MA, Haberman S, Levgur M. Cesarean scar ectopic pregnancies: etiology, diagnosis, and management. Obstet Gynecol. 2006;107(6):1373\u201381.","journal-title":"Obstet Gynecol"},{"issue":"8","key":"2590_CR2","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1007\/s00270-018-1934-z","volume":"41","author":"A Tumenjargal","year":"2018","unstructured":"Tumenjargal A, Tokue H, Kishi H, Hirasawa H, Taketomi-Takahashi A, Tsushima Y. Uterine artery embolization combined with dilation and curettage for the treatment of cesarean scar pregnancy: efficacy and future fertility. Cardiovasc Intervent Radiol. 2018;41(8):1165\u201373.","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"4","key":"2590_CR3","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1016\/j.fertnstert.2015.12.130","volume":"105","author":"K Birch Petersen","year":"2016","unstructured":"Birch Petersen K, Hoffmann E, Rifbjerg Larsen C, Svarre NH. Cesarean scar pregnancy: a systematic review of treatment studies. Fertil Steril. 2016;105(4):958\u201365.","journal-title":"Fertil Steril"},{"issue":"7","key":"2590_CR4","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1016\/j.jmig.2016.08.819","volume":"23","author":"B Qiao","year":"2016","unstructured":"Qiao B, Zhang Z, Li Y. Uterine artery embolization versus methotrexate for cesarean scar pregnancy in a Chinese population: a meta-analysis. J Minim Invasive Gynecol. 2016;23(7):1040\u20138.","journal-title":"J Minim Invasive Gynecol"},{"issue":"4","key":"2590_CR5","doi-asserted-by":"publisher","first-page":"989","DOI":"10.2214\/ajr.172.4.10587133","volume":"172","author":"JP Pelage","year":"1999","unstructured":"Pelage JP, Le Dref O, Soyer P, Jacob D, Kardache M, Dahan H, et al. Arterial anatomy of the female genital tract: variations and relevance to transcatheter embolization of the uterus. AJR Am J Roentgenol. 1999;172(4):989\u201394.","journal-title":"AJR Am J Roentgenol"},{"issue":"9","key":"2590_CR6","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1016\/S1051-0443(99)70215-0","volume":"10","author":"B Nikolic","year":"1999","unstructured":"Nikolic B, Spies JB, Abbara S, Goodwin SC. Ovarian artery supply of uterine fibroids as a cause of treatment failure after uterine artery embolization: a case report. J Vasc Interv Radiol. 1999;10(9):1167\u201370.","journal-title":"J Vasc Interv Radiol"},{"issue":"2","key":"2590_CR7","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/S0015-0282(97)81930-9","volume":"67","author":"PA Godin","year":"1997","unstructured":"Godin PA, Bassil S, Donnez J. An ectopic pregnancy developing in a previous cesarean scar. Fertil Steril. 1997;67(2):398\u2013400.","journal-title":"Fertil Steril"},{"issue":"2","key":"2590_CR8","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s00404-017-4426-5","volume":"296","author":"G Liu","year":"2017","unstructured":"Liu G, Wu J, Cao J, Xue Y, Dai C, Xu J, et al. Comparison of three treatment strategies for cesarean scar pregnancy. Arch Gynecol Obstet. 2017;296(2):383\u20139.","journal-title":"Arch Gynecol Obstet"},{"issue":"6","key":"2590_CR9","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1016\/j.fertnstert.2008.12.099","volume":"93","author":"R Deans","year":"2010","unstructured":"Deans R, Abbot J. Hysteroscopic management of cesarean scar ectopic pregnancy. Fertil Steril. 2010;93(6):1735\u201340.","journal-title":"Fertil Steril"},{"issue":"5","key":"2590_CR10","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1016\/j.fertnstert.2014.01.045","volume":"101","author":"G Wang","year":"2014","unstructured":"Wang G, Liu X, Bi F, Yin L, Sa R, Wang D, et al. Evaluation of the efficacy of laparoscopic resection for the management of exogenous cesarean scar pregnancy. Fertil Steril. 2014;101(5):1501\u20137.","journal-title":"Fertil Steril"},{"issue":"12","key":"2590_CR11","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.1097\/01.RVI.0000244851.04692.B5","volume":"17","author":"S Yousefi","year":"2006","unstructured":"Yousefi S, Czeyda-Pommersheim F, White A, Banovac F, Hahn WY, Spies JB. Repeat uterine artery embolization: indications and technical findings. J Vasc Interv Radiol. 2006;17(12):1923\u20139.","journal-title":"J Vasc Interv Radiol"},{"issue":"5","key":"2590_CR12","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/S1051-0443(07)61613-3","volume":"11","author":"RT Andrews","year":"2000","unstructured":"Andrews RT, Bromley PJ, Pfister ME. Successful embolization of collaterals from the ovarian artery during uterine artery embolization for fibroids: a case report. J Vasc Interv Radiol. 2000;11(5):607\u201310.","journal-title":"J Vasc Interv Radiol"},{"issue":"6","key":"2590_CR13","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1007\/s00270-010-9991-y","volume":"34","author":"C Scheurig-Muenkler","year":"2011","unstructured":"Scheurig-Muenkler C, Poellinger A, Wagner M, Hamm B, Kroencke TJ. Ovarian artery embolization in patients with collateral supply to symptomatic uterine leiomyomata. Cardiovasc Intervent Radiol. 2011;34(6):1199\u2013207.","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"1","key":"2590_CR14","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.bpobgyn.2017.09.003","volume":"46","author":"JJ Keung","year":"2018","unstructured":"Keung JJ, Spies JB, Caridi TM. Uterine artery embolization: a review of current concepts. Best Pract Res Clin Obstet Gynaecol. 2018;46(1):66\u201373.","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"3","key":"2590_CR15","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1148\/radiol.2343031697","volume":"234","author":"JP Pelage","year":"2005","unstructured":"Pelage JP, Jacob D, Fazel A, Namur J, Laurent A, Rymer R, et al. Midterm results of uterine artery embolization for symptomatic adenomyosis:initial experience. Radiology. 2005;234(3):948\u201353.","journal-title":"Radiology."},{"issue":"3","key":"2590_CR16","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1148\/radiol.2243011513","volume":"224","author":"MK Razavi","year":"2002","unstructured":"Razavi MK, Wolanske KA, Hwang GL, Sze DY, Kee ST, Dake MD. Angiographic classification of ovarian artery-touterine artery anastomoses: initial observations in uterine fibroid embolization. Radiology. 2002;224(3):707\u201312.","journal-title":"Radiology."}],"container-title":["BMC Pregnancy and Childbirth"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12884-019-2590-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12884-019-2590-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12884-019-2590-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T19:23:43Z","timestamp":1607973823000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpregnancychildbirth.biomedcentral.com\/articles\/10.1186\/s12884-019-2590-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["2590"],"URL":"https:\/\/doi.org\/10.1186\/s12884-019-2590-2","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.2.11587\/v2","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.2.11587\/v1","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.2.11587\/v4","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.2.11587\/v3","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.2.11587\/v5","asserted-by":"object"}]},"ISSN":["1471-2393"],"issn-type":[{"value":"1471-2393","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"24 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study complies with current ethical consideration and was approved by the institutional review board of Shandong medical imaging research institute and Shandong provincial hospital (decision number of our institutional ethics committee approval: JN-2012010038). All participants recruited in this study provided informed written consent.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"502"}}