{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T03:40:22Z","timestamp":1794627622056,"version":"4.9.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:00:00Z","timestamp":1611273600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:00:00Z","timestamp":1611273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011094","name":"Public Health Agency of Canada","doi-asserted-by":"crossref","award":["1718-HQ-000774"],"award-info":[{"award-number":["1718-HQ-000774"]}],"id":[{"id":"10.13039\/100011094","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pregnancy Childbirth"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The current study aimed to estimate the prevalence of alcohol use identified as a risk factor during pregnancies by the antenatal care providers, resulting in live births in British Columbia (BC) and to examine associations between alcohol use, adverse neonatal outcomes, and pregnancy complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This population-based cross-sectional study utilized linked obstetrical and neonatal records within the BC Perinatal Data Registry (BCPDR), for deliveries that were discharged between January 1, 2015 and March 31, 2018. The main outcome measures were alcohol use identified as a risk factor during pregnancy, associated maternal characteristics, pregnancy complications, and adverse neonatal outcomes. Estimates for the period and fiscal year prevalence were calculated. Chi-square tests were used to compare adverse neonatal outcomes and pregnancy complications by alcohol use during pregnancy\u00a0identified as a risk factor. Logistic regression was used to examine the association between alcohol use identified as a risk factor\u00a0during pregnancy and adverse neonatal outcomes and pregnancy complications, after adjusting for identified risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 144,779 linked records within the BCPDR were examined. The period prevalence of alcohol use during pregnancy identified as a risk factor was estimated to be 1.1% and yearly prevalence was 1.1, 1.1, 1.3 and 0.9% from the 2014\/2015 to 2017\/2018\u00a0fiscal years, respectively.<\/jats:p>\n                    <jats:p>Alcohol use identified as a risk factor\u00a0was associated with younger maternal age, fewer antenatal visits, being primiparous, a history of mental illness, substance use and smoking.<\/jats:p>\n                    <jats:p>Neonates with alcohol use during pregnancy identified as a risk factor had greater odds of being diagnosed with: \u201clow birth weight (1000-2499g)\u201d (ICD-10: P07.1; aOR\u2009=\u20091.25; 95% CI: 1.01, 1.53), \u201cother respiration distress of newborn\u201d (ICD-10: P22.8; aOR\u2009=\u20092.57; 95% CI: 1.52, 4.07), \u201cneonatal difficulty in breastfeeding\u201d (ICD-10: P92.5; aOR\u2009=\u20091.97; 95% CI: 1.27, 2.92) and \u201cfeeding problems, unspecified\u201d (ICD-10: P92.9; aOR\u2009=\u20092.06; 95% CI: 1.31, 3.09).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of alcohol use during pregnancy identified as a risk factor was comparable to previous estimates within the BCPDR. Identified prenatal alcohol exposure was associated with notable differences in maternal and neonatal characteristics and adverse neonatal outcomes. More consistent, thorough screening and prevention efforts targeting alcohol use in pregnancy are urgently needed in Canada.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12884-021-03545-7","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T02:03:21Z","timestamp":1611281001000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Maternal alcohol use, adverse neonatal outcomes and pregnancy complications in British Columbia, Canada: a population-based study"],"prefix":"10.1186","volume":"21","author":[{"given":"Svetlana","family":"Popova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danijela","family":"Dozet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"O\u2019Hanlon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Temple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Rehm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,22]]},"reference":[{"issue":"12","key":"3545_CR1","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.earlhumdev.2011.06.009","volume":"87","author":"A Alvik","year":"2011","unstructured":"Alvik A, Torgersen AM, Aalen OO, Lindemann R. 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All inferences, opinions, and conclusions drawn in this publication are those of the authors, and do not reflect the opinions or policies of Perinatal Services BC.This work was undertaken as part of a larger study supported by the Public Health Agency of Canada, for which ethics approval was received from the Centre for Addiction and Mental Health REB on 25 October 2017 (REB#: 014\/2017).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare that they do not have any <i>financial, personal, political, intellectual or religious competing interests<\/i> relevant to this article to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"74"}}