{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T11:58:33Z","timestamp":1764331113998,"version":"3.37.3"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pregnancy Childbirth"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Coronavirus Disease 2019 (COVID-19) is predominately known as a respiratory disease associated with pneumonia, acute respiratory distress syndrome and multiorgan failure. However, extra-pulmonary complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are increasingly being recognized. In this regard, some studies implied the hemostatic and vascular involvements in patients with SARS-CoV-2 infection.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We describe a case of spontaneous Intracerebral Hemorrhage (ICH) in a pregnant patient with COVID-19 and history of cesarean section a week before the occurrence of ICH. The patient underwent emergent craniotomy with acceptable outcome. Hemorrhagic events, including ICH, may happen during COVID-19 infection with several possible mechanisms.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>COVID-19 patients, especially high-risk groups, are at a risk of intracranial hemorrhage. Therefore, close follow-up must be maintained and hemorrhagic events must be kept in mind in these cases.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12884-021-04345-9","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T03:02:34Z","timestamp":1641438154000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Spontaneous Intracerebral Hemorrhage (ICH) associated with pregnancy and SARS-CoV-2 infection: a case report"],"prefix":"10.1186","volume":"22","author":[{"given":"Parisa","family":"Dini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soheila","family":"Aminimoghaddam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Mirzaasgari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda","family":"Rahimian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samaneh Tanhapour","family":"Khotbehsara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7039-7854","authenticated-orcid":false,"given":"Meysam","family":"Abolmaali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"4345_CR1","volume-title":"Novel coronavirus (2019-nCoV) situation report 1","author":"Organization WH","year":"2020","unstructured":"Organization WH. Novel coronavirus (2019-nCoV) situation report 1. 2020."},{"key":"4345_CR2","volume-title":"Coronavirus disease 2019 (COVID-19): situation report, 82","author":"Organization WH","year":"2020","unstructured":"Organization WH. Coronavirus disease 2019 (COVID-19): situation report, 82. 2020."},{"issue":"10223","key":"4345_CR3","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","volume":"395","author":"C Huang","year":"2020","unstructured":"Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497\u2013506.","journal-title":"Lancet"},{"issue":"10223","key":"4345_CR4","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/S0140-6736(20)30211-7","volume":"395","author":"N Chen","year":"2020","unstructured":"Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395(10223):507\u201313.","journal-title":"Lancet"},{"issue":"5","key":"4345_CR5","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1002\/uog.22189","volume":"56","author":"J Mongula","year":"2020","unstructured":"Mongula J, Frenken M, Van Lijnschoten G, Arents N, de Wit-Zuurendonk L, Schimmel-de Kok A, et al. COVID-19 during pregnancy: non-reassuring fetal heart rate, placental pathology and coagulopathy. Ultrasound Obstet Gynecol. 2020;56(5):773\u20136.","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"4345_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12884-020-03140-2","volume":"20","author":"KE Kinsey","year":"2020","unstructured":"Kinsey KE, Ganz E, Khalil S, Brustman L. Intraoperative coagulopathy during cesarean section as an unsuspected initial presentation of COVID-19: a case report. BMC Pregnancy Childbirth. 2020;20(1):1\u20133.","journal-title":"BMC Pregnancy Childbirth"},{"key":"4345_CR7","doi-asserted-by":"publisher","first-page":"e927521","DOI":"10.12659\/AJCR.927521","volume":"21","author":"W Takayama","year":"2020","unstructured":"Takayama W, Endo A, Yoshii J, Arai H, Oi K, Nagaoka E, et al. Severe COVID-19 pneumonia in a 30-year-old woman in the 36th week of pregnancy treated with postpartum extracorporeal membrane oxygenation. Am J Case Rep. 2020;21:e927521.","journal-title":"Am J Case Rep"},{"issue":"2","key":"4345_CR8","doi-asserted-by":"publisher","first-page":"89","DOI":"10.5830\/CVJA-2016-021","volume":"27","author":"P Soma-Pillay","year":"2016","unstructured":"Soma-Pillay P, Catherine N-P, Tolppanen H, Mebazaa A, Tolppanen H, Mebazaa A. Physiological changes in pregnancy. Cardiovasc J Afr. 2016;27(2):89.","journal-title":"Cardiovasc J Afr"},{"issue":"Suppl 1","key":"4345_CR9","doi-asserted-by":"publisher","first-page":"S24","DOI":"10.1093\/cid\/ciab344","volume":"73","author":"JY Ko","year":"2021","unstructured":"Ko JY, DeSisto CL, Simeone RM, Ellington S, Galang RR, Oduyebo T, et al. Adverse pregnancy outcomes, maternal complications, and severe illness among US delivery hospitalizations with and without a coronavirus disease 2019 (COVID-19) diagnosis. Clin Infect Dis. 2021;73(Suppl 1):S24\u2013s31.","journal-title":"Clin Infect Dis"},{"key":"4345_CR10","volume-title":"Verifying extra-pulmonary manifestation of COVID-19 in Firoozgar hospital 2020: an observational study","author":"A Mottaghi","year":"2021","unstructured":"Mottaghi A, Roham M, Makiani MJ, Ranjbar M, Laali A, Rahimian NR. Verifying extra-pulmonary manifestation of COVID-19 in Firoozgar hospital 2020: an observational study; 2021."},{"issue":"7","key":"4345_CR11","doi-asserted-by":"publisher","first-page":"2244","DOI":"10.3390\/jcm9072244","volume":"9","author":"MND Di Minno","year":"2020","unstructured":"Di Minno MND, Calcaterra I, Lupoli R, Storino A, Spedicato GA, Maniscalco M, et al. Hemostatic changes in patients with COVID-19: a meta-analysis with meta-regressions. J Clin Med. 2020;9(7):2244.","journal-title":"J Clin Med"},{"key":"4345_CR12","first-page":"1","volume":"42","author":"I Cheruiyot","year":"2020","unstructured":"Cheruiyot I, Sehmi P, Ominde B, Bundi P, Mislani M, Ngure B, et al. Intracranial hemorrhage in coronavirus disease 2019 (COVID-19) patients. Neurol Sci. 2020;42:1\u20139.","journal-title":"Neurol Sci"},{"issue":"4","key":"4345_CR13","doi-asserted-by":"publisher","first-page":"e202769","DOI":"10.1001\/jamanetworkopen.2020.2769","volume":"3","author":"JR Meeks","year":"2020","unstructured":"Meeks JR, Bambhroliya AB, Alex KM, Sheth SA, Savitz SI, Miller EC, et al. Association of primary intracerebral hemorrhage with pregnancy and the postpartum period. JAMA Netw Open. 2020;3(4):e202769.","journal-title":"JAMA Netw Open"}],"container-title":["BMC Pregnancy and Childbirth"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12884-021-04345-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12884-021-04345-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12884-021-04345-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T03:03:53Z","timestamp":1641438233000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpregnancychildbirth.biomedcentral.com\/articles\/10.1186\/s12884-021-04345-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,6]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["4345"],"URL":"https:\/\/doi.org\/10.1186\/s12884-021-04345-9","relation":{},"ISSN":["1471-2393"],"issn-type":[{"type":"electronic","value":"1471-2393"}],"subject":[],"published":{"date-parts":[[2022,1,6]]},"assertion":[{"value":"28 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in accordance with the declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this Case report and any accompanying images. A copy of the written consent is available for review by the Editor of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"14"}}