{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:12:11Z","timestamp":1784121131973,"version":"3.55.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pregnancy Childbirth"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Non-communicating rudimentary horn pregnancy (NCRHP) lead to life-threatening condition for both mother and fetus. Early diagnosis of NCRHP and laparoscopic resection is important to prevent catastrophic conditions. However, delayed diagnosis until the second or third trimester makes it difficult to accurately diagnose between NCRHP and bicornuate uterine pregnancy, as both conditions present uterine rupture and massive hemoperitoneum. Furthermore, these rare cases are challenging in pregnancy trials and associated with adverse outcomes in subsequent pregnancies.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 31-year-old gravida 1 para 0 Korean woman visited our infertility center with a confirmed positive urine pregnancy test after timed intercourse. Before she was scheduled to have timed intercourse, a unicornuate uterus with a non-communicating right uterine horn was suspected based on an ultrasound scan and hysterosalpingography during the initial infertility workup. A gestational sac was observed in the right non-communicating rudimentary horn at 5\u00a0weeks of gestation. Serum beta-human chorionic gonadotropin (b-hCG) level was 2052.0mIU\/mL. An elective laparoscopic resection of the right rudimentary horn containing a gestational sac, along with ipsilateral salpingectomy, was performed with no adverse event. After 3-month of recovery period and three cycles of conceptional trials involving timed intercourse and intrauterine insemination, in-vitro fertilization (IVF) was performed using the antagonist protocol, and successful pregnancy was confirmed. The patient had been hospitalized from 21\u2009+\u20096\u00a0weeks to 35\u2009+\u20096\u00a0weeks of gestation, underwent cerclage placement and tocolytics with corticosteroid treatment. She delivered an early-term male baby by cesarean section.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In this rare case, the successful pregnancy achieved through IVF following the appropriate management of NCRHP under laparoscopy underscores the critical importance of early diagnosis and intervention in cases of NCRHP. Timely identification and management of NCRHP are vital to prevent the occurrence of catastrophic conditions and to enhance the prognosis of a successful pregnancy through assisted reproductive technology (ART). Therefore, a high index of suspicion for NCRHP is important and employs a range of diagnostic modalities.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12884-024-06289-2","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T12:02:27Z","timestamp":1707307347000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Successful pregnancy outcome via in-vitro fertilization and laparoscopic resection of non-communicating rudimentary horn pregnancy containing early pregnancy: a case report"],"prefix":"10.1186","volume":"24","author":[{"given":"So Yeon","family":"Shin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwang","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Chul","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Jung","family":"Baek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Eun","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"issue":"1","key":"6289_CR1","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1186\/s12884-021-04195-5","volume":"21","author":"M Ueda","year":"2021","unstructured":"Ueda M, Ota K, Takahashi T, Suzuki S, Suzuki D, Kyozuka H, et al. Successful pregnancy and term delivery after treatment of unicornuate uterus with non-communicating rudimentary horn pregnancy with local methotrexate injection followed by laparoscopic resection: a case report and literature review. BMC Pregnancy Childbirth. 2021;21(1):715.","journal-title":"BMC Pregnancy Childbirth"},{"key":"6289_CR2","first-page":"1489751","volume":"2019","author":"MG Tesemma","year":"2019","unstructured":"Tesemma MG. Pregnancy in noncommunicating rudimentary horn of unicornuate uterus: a case report and review of the literature. Case Rep Obstet Gynecol. 2019;2019:1489751.","journal-title":"Case Rep Obstet Gynecol"},{"issue":"2","key":"6289_CR3","doi-asserted-by":"publisher","first-page":"201","DOI":"10.15537\/smj.2017.2.16016","volume":"38","author":"AA Al Qarni","year":"2017","unstructured":"Al Qarni AA, Al-Braikan N, Al-Hanbali MM, Alharmaly AH. Rupture rudimentary horn pregnancy at 31 week. Saudi Med J. 2017;38(2):201\u20133.","journal-title":"Saudi Med J"},{"issue":"3","key":"6289_CR4","first-page":"e7191","volume":"12","author":"M Bruand","year":"2020","unstructured":"Bruand M, Thubert T, Winer N, Gueudry P, Dochez V. Rupture of non-communicating rudimentary horn of uterus at 12 weeks\u2019 gestation. Cureus. 2020;12(3):e7191.","journal-title":"Cureus"},{"issue":"2","key":"6289_CR5","first-page":"92","volume":"23","author":"IM Cobec","year":"2019","unstructured":"Cobec IM, Seropian P, Rempen A. Pregnancy in a non-communicating rudimentary horn of a unicornuate uterus. Hippokratia. 2019;23(2):92\u20134.","journal-title":"Hippokratia"},{"issue":"2","key":"6289_CR6","first-page":"59","volume":"39","author":"Y Kanno","year":"2014","unstructured":"Kanno Y, Suzuki T, Nakamura E, Goya K, Nishijima Y, Shinoda M, et al. Successful term delivery after laparoscopic resection of a non-communicating rudimentary horn in a patient with a unicornuate uterus: a case report. Tokai J Exp Clin Med. 2014;39(2):59\u201363.","journal-title":"Tokai J Exp Clin Med"},{"issue":"1","key":"6289_CR7","doi-asserted-by":"publisher","first-page":"7","DOI":"10.4103\/GMIT.GMIT_157_20","volume":"11","author":"W Isono","year":"2022","unstructured":"Isono W, Tsuchiya A, Honda M, Saito A, Tsuchiya H, Matsuyama R, et al. Successful management of a noncommunicating rudimentary uterine horn pregnancy by laparoscopic surgery: a case report and literature review. Gynecol Minim Invasive Ther. 2022;11(1):7\u201316.","journal-title":"Gynecol Minim Invasive Ther"},{"issue":"1","key":"6289_CR8","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1002\/uog.26073","volume":"61","author":"T Tellum","year":"2023","unstructured":"Tellum T, Bracco B, De Braud LV, Knez J, Ashton-Barnett R, Amin T, et al. Reproductive outcome in 326 women with unicornuate uterus. Ultrasound Obstet Gynecol. 2023;61(1):99\u2013108.","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"6","key":"6289_CR9","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1097\/01.AOG.0000161321.94364.56","volume":"105","author":"Y Jayasinghe","year":"2005","unstructured":"Jayasinghe Y, Rane A, Stalewski H, Grover S. The presentation and early diagnosis of the rudimentary uterine horn. Obstet Gynecol. 2005;105(6):1456\u201367.","journal-title":"Obstet Gynecol"}],"container-title":["BMC Pregnancy and Childbirth"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12884-024-06289-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12884-024-06289-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12884-024-06289-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T12:09:06Z","timestamp":1707307746000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpregnancychildbirth.biomedcentral.com\/articles\/10.1186\/s12884-024-06289-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,7]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["6289"],"URL":"https:\/\/doi.org\/10.1186\/s12884-024-06289-2","relation":{},"ISSN":["1471-2393"],"issn-type":[{"value":"1471-2393","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,7]]},"assertion":[{"value":"10 September 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This case report was approved by the Institutional Review Board of CHA University Bundang Medical Center.As this publication concerns single patient data in the form of a case report, and ethics approval by the Institutional Review Board of CHA University Bundang Medical Center.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors have obtained written informed consent from the patient to publish this case report and any accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"115"}}