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L2025SYSU-HL-006; August 6, 2025). Both partners will provide written informed consent before participation. Any protocol amendments will be communicated to the ethics committee, trial registry, and relevant stakeholders.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"430"}}