{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:54:42Z","timestamp":1781643282503,"version":"3.54.5"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":38,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100015769","name":"Dexcom","doi-asserted-by":"publisher","award":["Reference # IIS-2021-120"],"award-info":[{"award-number":["Reference # IIS-2021-120"]}],"id":[{"id":"10.13039\/100015769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pregnancy Childbirth"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Continuous glucose monitoring (CGM) improves maternal and neonatal outcomes in pregnancies complicated by preconception diabetes. CGM measurements may help optimize intrapartum and postpartum glycemic management in pregnant women with GDM. We investigated the use of blinded CGM-derived metrics during labor, delivery, and postpartum supplementary to normally monitored glucose measures in women with GDM to study neonatal outcomes and postpartum glucose metabolism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective observational study evaluated 60 pregnant women with gestational diabetes mellitus (GDM) during the peripartum and postpartum periods. Of these, 35% were managed with diet alone, while 65% required pharmacologic therapy (insulin, metformin, or both). Participants wore a blinded continuous glucose monitor (Dexcom G6 Pro) for 10 days, beginning 1\u20133 days before delivery. At 6\u201318 weeks postpartum, all underwent a 75-g oral glucose tolerance test (OGTT), with a subset (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200928) also using blinded CGM. Univariate and logistic regression analyses assessed associations between CGM metrics in the 24\u00a0h preceding delivery and neonatal hypoglycemia or NICU admission.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Infants of women having an induced vaginal or unplanned caesarean delivery (C-section) were significantly more likely than infants delivered by repeat C-section to have neonatal hypoglycemia (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005). No significant correlations between maternal CGM-derived metrics and postnatal adaptation in the newborn were found and none of the models trained to predict neonatal hypoglycemia or intensive unit (NICU) admission showed satisfactory power. While only modest associations between postdelivery CGM metrics and postpartum OGTT values were observed, there were strong correlations between postpartum CGM metrics and OGTT-derived values.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In GDM, intrapartum CGM-based metrics were not associated with adverse neonatal outcomes. Future investigations with a larger cohort are needed to assess intra-and postpartum CGM-metrics in women with GDM and their association with neonatal outcomes and OGTT results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>ClinicalTrials.gov, NCT05067075 (initiation 11\/1\/2021).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12884-026-08944-2","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T12:47:04Z","timestamp":1773665224000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Relationship between continuous maternal intrapartum and postpartum glucose monitoring metrics and neonatal outcomes and postpartum glucose metabolism in individuals with gestational diabetes"],"prefix":"10.1186","volume":"26","author":[{"given":"Karen E.","family":"Elkind-Hirsch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Missy","family":"Armatta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Veillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Schiavon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Cappon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"issue":"19","key":"8944_CR1","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1056\/NEJMoa0707943","volume":"358","author":"BE Metzger","year":"2008","unstructured":"Hapo Study Cooperative Research Group, Metzger BE, Lowe LP, et al. 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The protocol was approved by the Woman\u2019s Hospital Foundation Institutional Review Board of Woman\u2019s Hospital where the study was carried out.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Karen Elkind-Hirsch reports receiving grant support from Dexcom, Inc. and Novo Nordisk and has served on an advisory board for Lilly and NovoNordisk. She now is an employee for Dexcom, Inc., Missy Armatta, Edward Veillon, Sara Schiavon, and Giacomo Cappon have nothing to disclose. No other potential conflict of interest relevant to this article exists.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"450"}}