{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T10:49:44Z","timestamp":1740134984935,"version":"3.37.3"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["2015M2A2A7055063","50595-2016"],"award-info":[{"award-number":["2015M2A2A7055063","50595-2016"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["H14C3459"],"award-info":[{"award-number":["H14C3459"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12885-017-3571-3","type":"journal-article","created":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T14:31:51Z","timestamp":1504103511000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chemoradiotherapy versus surgery followed by postoperative radiotherapy in tonsil cancer: Korean Radiation Oncology Group (KROG) study"],"prefix":"10.1186","volume":"17","author":[{"given":"Sanghyuk","family":"Song","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Gyun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang Geol","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki Chang","family":"Keum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Sun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Chan","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongryul","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo Jung","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Wook","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geumju","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Ho","family":"Moon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwan Ho","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeon-Sil","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongkyun","family":"Won","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Taek","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won-Taek","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Uk","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,8,30]]},"reference":[{"key":"3571_CR1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1097\/MOO.0b013e32832984c0","volume":"17","author":"DM Cohan","year":"2009","unstructured":"Cohan DM, Popat S, Kaplan SE, Rigual N, Loree T, Hicks WL Jr. Oropharyngeal cancer: current understanding and management. Curr Opin Otolaryngol Head Neck Surg. 2009;17:88\u201394.","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"3571_CR2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1749-4486.2011.02361.x","volume":"36","author":"O Olaleye","year":"2011","unstructured":"Olaleye O, Moorthy R, Lyne O, Black M, Mitchell D, Wiseberg J. A 20-year retrospective study of tonsil cancer incidence and survival trends in South East England: 1987-2006. Clin Otolaryngol. 2011;36:325\u201335.","journal-title":"Clin Otolaryngol"},{"key":"3571_CR3","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1002\/lary.21129","volume":"120","author":"V Mehta","year":"2010","unstructured":"Mehta V, Yu GP, Schantz SP. Population-based analysis of oral and oropharyngeal carcinoma: changing trends of histopathologic differentiation, survival and patient demographics. Laryngoscope. 2010;120:2203\u201312.","journal-title":"Laryngoscope"},{"key":"3571_CR4","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.oraloncology.2011.05.013","volume":"47","author":"EJ Chung","year":"2011","unstructured":"Chung EJ, Oh JI, Choi KY, et al. Pattern of cervical lymph node metastasis in tonsil cancer: predictive factor analysis of contralateral and retropharyngeal lymph node metastasis. Oral Oncol. 2011;47:758\u201362.","journal-title":"Oral Oncol"},{"key":"3571_CR5","first-page":"1237","volume":"33","author":"G Park","year":"2013","unstructured":"Park G, Lee SW, Kim SY, et al. Can concurrent chemoradiotherapy replace surgery and postoperative radiation for locally advanced stage III\/IV tonsillar squamous cell carcinoma? Anticancer Res. 2013;33:1237\u201343.","journal-title":"Anticancer Res"},{"key":"3571_CR6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.4143\/crt.2012.44.4.227","volume":"44","author":"TR Koo","year":"2012","unstructured":"Koo TR, Wu HG, Hah JH, et al. Definitive radiotherapy versus postoperative radiotherapy for tonsil cancer. Cancer Res Treat. 2012;44:227\u201334.","journal-title":"Cancer Res Treat"},{"key":"3571_CR7","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1200\/JCO.2000.18.11.2219","volume":"18","author":"WM Mendenhall","year":"2000","unstructured":"Mendenhall WM, Amdur RJ, Stringer SP, Villaret DB, Cassisi NJ. Radiation therapy for squamous cell carcinoma of the tonsillar region: a preferred alternative to surgery? J Clin Oncol. 2000;18:2219\u201325.","journal-title":"J Clin Oncol"},{"key":"3571_CR8","unstructured":"NCCN Guidelines Panels. NCCN clinical practice guidelines in oncology: head and neck cancers. Available from URL: https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/head-and-neck.pdf . Accessed 29 Aug 2017."},{"key":"3571_CR9","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1093\/jnci\/91.24.2081","volume":"91","author":"G Calais","year":"1999","unstructured":"Calais G, Alfonsi M, Bardet E, et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst. 1999;91:2081\u20136.","journal-title":"J Natl Cancer Inst"},{"key":"3571_CR10","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1056\/NEJMoa032646","volume":"350","author":"JS Cooper","year":"2004","unstructured":"Cooper JS, Pajak TF, Forastiere AA, et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med. 2004;350:1937\u201344.","journal-title":"N Engl J Med"},{"key":"3571_CR11","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1056\/NEJMoa0912217","volume":"363","author":"KK Ang","year":"2010","unstructured":"Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010;363:24\u201335.","journal-title":"N Engl J Med"},{"key":"3571_CR12","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s12105-009-0100-y","volume":"3","author":"WH Westra","year":"2009","unstructured":"Westra WH. The changing face of head and neck cancer in the 21st century: the impact of HPV on the epidemiology and pathology of oral cancer. Head Neck Pathol. 2009;3:78\u201381.","journal-title":"Head Neck Pathol"},{"key":"3571_CR13","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/sj.bjc.6602696","volume":"93","author":"KC Soo","year":"2005","unstructured":"Soo KC, Tan EH, Wee J, et al. Surgery and adjuvant radiotherapy vs concurrent chemoradiotherapy in stage III\/IV nonmetastatic squamous cell head and neck cancer: a randomised comparison. Br J Cancer. 2005;93:279\u201386.","journal-title":"Br J Cancer"},{"key":"3571_CR14","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1007\/s00405-012-2335-6","volume":"270","author":"M Canis","year":"2013","unstructured":"Canis M, Martin A, Kron M, et al. Results of transoral laser microsurgery in 102 patients with squamous cell carcinoma of the tonsil. Eur Arch Otorhinolaryngol. 2013;270:2299\u2013306.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"3571_CR15","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/hed.21207","volume":"32","author":"G Yildirim","year":"2010","unstructured":"Yildirim G, Morrison WH, Rosenthal DI, et al. Outcomes of patients with tonsillar carcinoma treated with post-tonsillectomy radiation therapy. Head Neck. 2010;32:473\u201380.","journal-title":"Head Neck"},{"key":"3571_CR16","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/01.mlg.0000243044.91193.32","volume":"117","author":"M Poulsen","year":"2007","unstructured":"Poulsen M, Porceddu SV, Kingsley PA, Tripcony L, Coman W. Locally advanced tonsillar squamous cell carcinoma: treatment approach revisited. Laryngoscope. 2007;117:45\u201350.","journal-title":"Laryngoscope"},{"key":"3571_CR17","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/01.coc.0000209510.19360.f9","volume":"29","author":"WM Mendenhall","year":"2006","unstructured":"Mendenhall WM, Morris CG, Amdur RJ, et al. Definitive radiotherapy for tonsillar squamous cell carcinoma. Am J Clin Oncol. 2006;29:290\u20137.","journal-title":"Am J Clin Oncol"},{"key":"3571_CR18","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/0360-3016(94)90309-3","volume":"30","author":"M Pernot","year":"1994","unstructured":"Pernot M, Malissard L, Hoffstetter S, et al. Influence of tumoral, radiobiological, and general factors on local-control and survival of a series of 361 tumors of the velotonsillar area treated by exclusive irradiation (external-beam irradiation plus brachytherapy or brachytherapy alone). Int J Radiat Oncol Biol Phys. 1994;30:1051\u20137.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"3571_CR19","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0360-3016(98)00291-0","volume":"42","author":"CA Perez","year":"1998","unstructured":"Perez CA, Patel MM, Chao KSC, et al. Carcinoma of the tonsillar fossa: prognostic factors and long-term therapy outcome. Int J Radiat Oncol BiolPhys. 1998;42:1077\u201384.","journal-title":"Int J Radiat Oncol BiolPhys"},{"key":"3571_CR20","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S1470-2045(13)70011-1","volume":"14","author":"R Haddad","year":"2013","unstructured":"Haddad R, O'Neill A, Rabinowits G, et al. Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial. Lancet Oncol. 2013;14:257\u201364.","journal-title":"Lancet Oncol"},{"key":"3571_CR21","doi-asserted-by":"crossref","unstructured":"Cohen EEW, Karrison T, Kocherginsky M, et al. DeCIDE: a phase III randomized trial of docetaxel (D), cisplatin (P), 5-fluorouracil (F) (TPF) induction chemotherapy (IC) in patients with N2\/N3 locally advanced squamous cell carcinoma of the head and neck (SCCHN). ASCO Meeting Abstracts. 2012;30: 5500.","DOI":"10.1200\/jco.2012.30.15_suppl.5500"},{"key":"3571_CR22","doi-asserted-by":"crossref","first-page":"489","DOI":"10.4065\/83.4.489","volume":"83","author":"S Marur","year":"2008","unstructured":"Marur S, Forastiere AA. Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc. 2008;83:489\u2013501.","journal-title":"Mayo Clin Proc"},{"key":"3571_CR23","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1080\/02841860902845839","volume":"48","author":"JP Agarwal","year":"2009","unstructured":"Agarwal JP, Mallick I, Bhutani R, et al. Prognostic factors in oropharyngeal cancer--analysis of 627 cases receiving definitive radiotherapy. Acta Oncol. 2009;48:1026\u201333.","journal-title":"Acta Oncol"},{"key":"3571_CR24","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1038\/sj.bjc.6603394","volume":"95","author":"CC Ragin","year":"2006","unstructured":"Ragin CC, Taioli E, Weissfeld JL, et al. 11q13 amplification status and human papillomavirus in relation to p16 expression defines two distinct etiologies of head and neck tumours. Br J Cancer. 2006;95:1432\u20138.","journal-title":"Br J Cancer"},{"issue":"3","key":"3571_CR25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1056\/NEJM199301213280302","volume":"328","author":"GP Browman","year":"1993","unstructured":"Browman GP, Wong G, Hodson I, et al. Influence of cigarette smoking on the efficacy of radiation therapy in head and neck cancer. N Engl J Med. 1993;328(3):159\u201363.","journal-title":"N Engl J Med"},{"issue":"12","key":"3571_CR26","doi-asserted-by":"crossref","first-page":"djv344","DOI":"10.1093\/jnci\/djv344","volume":"107","author":"EE Vokes","year":"2015","unstructured":"Vokes EE, Agrawal N, Seiwert TY. HPV-associated head and neck cancer. J Natl Cancer Inst. 2015;107(12):djv344.","journal-title":"J Natl Cancer Inst"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12885-017-3571-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T15:44:27Z","timestamp":1719416667000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/s12885-017-3571-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,30]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["3571"],"URL":"https:\/\/doi.org\/10.1186\/s12885-017-3571-3","relation":{},"ISSN":["1471-2407"],"issn-type":[{"type":"electronic","value":"1471-2407"}],"subject":[],"published":{"date-parts":[[2017,8,30]]},"article-number":"598"}}