{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T19:09:37Z","timestamp":1788894577938,"version":"build-2803163510"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T00:00:00Z","timestamp":1552003200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"MEDeA onlus"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12885-019-5366-1","type":"journal-article","created":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T13:03:09Z","timestamp":1552050189000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Epidemiological, clinical and pathological characteristics of gastric neoplasms in the province of Cremona: the experience of the first population-based specialized gastric cancer registry in Italy"],"prefix":"10.1186","volume":"19","author":[{"given":"B. M.","family":"Donida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Tomasello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ghidini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Buffoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Grassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Liguigli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Maglietta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Pergola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ratti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Sabadini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Toppo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ungari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Passalacqua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,3,8]]},"reference":[{"key":"5366_CR1","unstructured":"Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. GLOBOCAN 2012 v1.0, Cancer incidence and mortality worldwide: IARC Cancer Base No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013. Available from: \n                    http:\/\/globocan.iarc.fr\n                    \n                  ; accessed on 26th Nov 2017."},{"key":"5366_CR2","doi-asserted-by":"publisher","first-page":"74e108","DOI":"10.3322\/canjclin.55.2.74","volume":"55","author":"DM Parkin","year":"2005","unstructured":"Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74e108.","journal-title":"CA Cancer J Clin"},{"key":"5366_CR3","doi-asserted-by":"publisher","first-page":"23e34","DOI":"10.1016\/S1470-2045(13)70546-1","volume":"15","author":"R Angelis De","year":"2014","unstructured":"De Angelis R, Sant M, Coleman MP, Francisci S, Baili P, Pierannunzio D, et al. Cancer survival in Europe 1999e2007 by country and age: results of UROCAREe5-a population-based study. Lancet Oncol. 2014;15:23e34.","journal-title":"Lancet Oncol"},{"issue":"12","key":"5366_CR4","doi-asserted-by":"publisher","first-page":"3027","DOI":"10.1007\/s10620-014-3275-3","volume":"59","author":"FH Lui","year":"2014","unstructured":"Lui FH, Tuan B, Swenson SL, Wong RJ. Ethnic disparities in gastric cancer incidence and survival in the USA: an updated analysis of 1992e2009 SEER data. Dig Dis Sci. 2014;59(12):3027\u201334.","journal-title":"Dig Dis Sci"},{"issue":"9","key":"5366_CR5","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1136\/gutjnl-2015-309252","volume":"64","author":"K Sugano","year":"2015","unstructured":"Sugano K, Tack J, Kuipers EJ, Graham DY, El-Omar EM, Miura S, et al. Kyoto global consensus report on helicobacter pylori gastritis. Gut. 2015;64(9):1353\u201367.","journal-title":"Gut"},{"issue":"2","key":"5366_CR6","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.gie.2008.11.046","volume":"70","author":"T Tahara","year":"2009","unstructured":"Tahara T, Shibata T, Nakamura M, Yoshioka D, Okubo M, Arisawa T, et al. Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis. Gastrointest Endosc. 2009;70(2):246\u201353.","journal-title":"Gastrointest Endosc"},{"key":"5366_CR7","unstructured":"I numeri del cancro in Italia 2017, Aiom-AIRTum, Intermedia Ed, 2017."},{"issue":"4","key":"5366_CR8","first-page":"453","volume":"32","author":"C Cislaghi","year":"1996","unstructured":"Cislaghi C, Dal Cason M, Tasco C, Braga M. Geographic distribution of digestive system tumour mortality in Italy, 1970-87. Ann Ist Super Sanit\u00e0. 1996;32(4):453\u201369.","journal-title":"Ann Ist Super Sanit\u00e0"},{"issue":"7","key":"5366_CR9","doi-asserted-by":"publisher","first-page":"156","DOI":"10.4251\/wjgo.v4.i7.156","volume":"4","author":"S Nagini","year":"2012","unstructured":"Nagini S. Carcinoma of the stomach: a review of epidemiology, pathogenesis, molecular genetics and chemoprevention. World J Gastrointest Oncol. 2012;4(7):156\u201369.","journal-title":"World J Gastrointest Oncol"},{"key":"5366_CR10","unstructured":"Ferretti S et AIRTum working group, Manuale di Tecniche di Registrazione dei Tumori, Inferenze Scarl, ed. 2007."},{"key":"5366_CR11","unstructured":"Cancer Registration: Principles and Methods, World Health Organization International Agency for Research on Cancer and International Association of Cancer Registries. In: Jensen OM, Parkin DM, MacLennan R, Muir CS, Skeet RG, editors. IARC Scientific Publication No. 95, 1991. ISBN 92 832 1195 2."},{"key":"5366_CR12","unstructured":"International Agency for Research on Cancer IARC. Cancer in 5 continents. In: Waterhouse JAH, Muir CS, Shanmugaratnam K, Powell J, editors. IARC Scientific Publication no. 42., 1982. ISBN 978\u201392\u2013832-1142-6."},{"key":"5366_CR13","unstructured":"TNM Classification of Malignant Tumours, 7th edition. In: Sobin LH, Gospodarowicz MK, Wittekind C, editors. Oxford: Wiley-Blackwell 2011. ISBN 978\u20131\u2013444-35896-4."},{"key":"5366_CR14","volume-title":"New York","author":"AJCC Cancer Staging Manual","year":"2010","unstructured":"Cancer Staging Manual AJCC. 7th edition. In: Edge S, Byrd DR, Compton CC, Fritz AG, Greene F, Trotti A, editors. New York. NY: Springer; 2010."},{"key":"5366_CR15","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/j.1751-2980.2011.00550.x","volume":"13","author":"P Correa","year":"2012","unstructured":"Correa P, Piazuelo MB. The gastric precancerous cascade. J Dig Dis. 2012;13:2\u20139.","journal-title":"J Dig Dis"},{"key":"5366_CR16","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/apm.1965.64.1.31","volume":"64","author":"P Lauren","year":"1965","unstructured":"Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand. 1965;64:31\u201349.","journal-title":"Acta Pathol Microbiol Scand"},{"issue":"3","key":"5366_CR17","first-page":"172","volume":"83","author":"G Corso","year":"2012","unstructured":"Corso G, Seruca R, Roviello F. Gastric cancer carcinogenesis and tumour progression. Ann Ital Chir. 2012;83(3):172\u20136 PMID: 22595727.","journal-title":"Ann Ital Chir"},{"key":"5366_CR18","unstructured":"European Medicines Agency. Committee for medicinal products for human use post-authorisation summary of positive opinion for Herceptin 2009. \n                    \n                      http:\/\/www.ema.europa.eu\/ema\/index.jsp?curl=pages\/medicines\/human\/medicines\/000278\/human_med_000818.jsp&mid=WC0b01ac058001d124\n                    \n                    \n                   (last accessed on May 25 2018)."},{"key":"5366_CR19","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1136\/jmedgenet-2015-103094","volume":"52","author":"RS Post Van der","year":"2015","unstructured":"Van der Post RS, Vogelaar IP, Carneiro F, Guilford P, Huntsman D, Hoogerbrugge N, et al. Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers. J Med Genet. 2015;52:361\u201374.","journal-title":"J Med Genet"},{"issue":"7","key":"5366_CR20","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1136\/jmg.2009.074237","volume":"47","author":"RC Fitzgerald","year":"2010","unstructured":"Fitzgerald RC, Hardwick R, Huntsman D, Carneiro F, Guilford P, Blair V, et al. Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research. J Med Genet. 2010;47(7):436\u201344.","journal-title":"J Med Genet"},{"issue":"3","key":"5366_CR21","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s10689-012-9521-y","volume":"11","author":"I Kluijt","year":"2012","unstructured":"Kluijt I, Sijmons RH, Hoogerbrugge N, Plukker JT, de Jong D, van Krieken JH, et al. Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance. Fam Cancer. 2012;11(3):363\u20139. 50.","journal-title":"Fam Cancer"},{"key":"5366_CR22","unstructured":"http:\/\/dati.istat.it\/Index.aspx?DataSetCode=DCIS_POPRES1\n                    \n                   (last accessed on May 25 2018)."},{"key":"5366_CR23","unstructured":"Cancer incidence in five continents. In: Waterhouse JAH, Muir CS, Correa P, Powell J, editors. Lyon: IARC, 1976; Vol. 3: 456."},{"key":"5366_CR24","unstructured":"Eurostat European Commission. Revision of the Standard Population. Ed. European Union, 2013, ISSN 1977\u20130375, available at \n                    http:\/\/europa.eu\n                    \n                   (last accessed on May 25 2018)."},{"key":"5366_CR25","unstructured":"Cancer Mortality for Selected Sites in 24 Countries (1950\u201357). In: Segi M editor. Department of Public Health, Tohoku University of Medicine, Sendai, Japan, 1960."},{"key":"5366_CR26","unstructured":"Cancer Incidence in Five Continents. In: Doll, R, Payne, P, Waterhouse, JAH, editors Vol. I, 1966. Union Internationale Contre le Cancer, Geneva."},{"key":"5366_CR27","doi-asserted-by":"publisher","first-page":"E359","DOI":"10.1002\/ijc.29210","volume":"136","author":"J Ferlay","year":"2015","unstructured":"Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136:E359\u201386.","journal-title":"Int J Cancer"},{"key":"5366_CR28","unstructured":"Joinpoint Regression Program, Version 4.0.4. 2013; \n                    http:\/\/surveillance.cancer.gov\/joinpoint\/\n                    \n                  . (last accessed May 25 2018)."},{"issue":"3","key":"5366_CR29","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1002\/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z","volume":"19","author":"HJ Kim","year":"2000","unstructured":"Kim HJ, Fay MP, Feuer EJ, Midthune DN. Permutation tests for join point regression with applications to cancer rates. Stat Med. 2000;19(3):335\u201351.","journal-title":"Stat Med"},{"key":"5366_CR30","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/0021-9681(77)90036-4","volume":"30","author":"T Hakulinen","year":"1977","unstructured":"Hakulinen T. On long-term relative survival rates. J Chronic Dis. 1977;30:431\u201343.","journal-title":"J Chronic Dis"},{"key":"5366_CR31","doi-asserted-by":"publisher","first-page":"2494","DOI":"10.1016\/j.ejca.2004.07.022","volume":"40","author":"H Brenner","year":"2004","unstructured":"Brenner H, Rachet B. Hybrid analysis for up-to-date long-term survival rates in cancer registries with delayed recording of incident cases. Eur J Cancer. 2004;40:2494\u2013501.","journal-title":"Eur J Cancer"},{"key":"5366_CR32","doi-asserted-by":"publisher","first-page":"2004","DOI":"10.1002\/(SICI)1097-0142(19961101)78:9<2004::AID-CNCR23>3.0.CO;2-#","volume":"78","author":"H Brenner","year":"1996","unstructured":"Brenner H, Gefeller O. An alternative approach to monitoring cancer patient survival. Cancer. 1996;78:2004\u201310.","journal-title":"Cancer"},{"key":"5366_CR33","unstructured":"Ederer F, Heise H. 1959. Instructions to IBM 650 programmers in processing survival computations. Methodological note 10. End results evaluation section, National Cancer Institute, Bethesda, MD; 1959."},{"key":"5366_CR34","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","volume":"53","author":"EL Kaplan","year":"1958","unstructured":"Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457\u201381.","journal-title":"J Am Stat Assoc"},{"key":"5366_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/bjc.1977.1","volume":"35","author":"R Peto","year":"1977","unstructured":"Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II Analysis and examples. Br J Cancer. 1977;35:1\u201339.","journal-title":"Br J Cancer"},{"key":"5366_CR36","unstructured":"Forman D, Sierra MS. The current and projected global burden of gastric cancer. In: IARC Helicobacter pylori Working Group Helicobacter pylori. Eradication as a Strategy for Preventing Gastric Cancer. Lyon, France: International Agency for Research on Cancer (IARC Working Group Reports, No. 8, 2014), 5\u201315. Available from: \n                    http:\/\/publications.iarc.fr\/Book-And-Report-Series\/Iarc-Working-Group-Reports\/-Em-Helicobacter-Pylori-Em-Eradication-As-A-Strategy-For-Preventing-Gastric-Cancer-2014\n                    \n                  . Accessed 21 Feb 2019."},{"key":"5366_CR37","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/j.bpg.2006.03.013","volume":"20","author":"RC Fitzgerald","year":"2006","unstructured":"Fitzgerald RC, Caldas C. Familial gastric cancer-clinical management. Best Pract Res Gastroenterol. 2006;20:735\u201343.","journal-title":"Best Pract Res Gastroenterol"},{"key":"5366_CR38","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1007\/s10689-012-9595-6","volume":"12","author":"S Kim","year":"2013","unstructured":"Kim S, Chung JW, Jeong TD, Park YS, Lee JH, Ahn JY, et al. Searching for E-cadherin gene mutations in early onset diffuse gastric cancer and hereditary diffuse gastric cancer in Korean patients. Familial Cancer. 2013;12:503\u20137.52.","journal-title":"Familial Cancer"},{"key":"5366_CR39","doi-asserted-by":"publisher","first-page":"386","DOI":"10.3343\/alm.2014.34.5.386","volume":"34","author":"HJ Choi","year":"2014","unstructured":"Choi HJ, Ki CS, Suh SP, Kim JW. Presymptomatic identification of CDH1 germline mutation in a healthy korean individual with family history of gastric cancer. Ann Lab Med. 2014;34:386\u20139.","journal-title":"Ann Lab Med"},{"key":"5366_CR40","doi-asserted-by":"crossref","unstructured":"Guilford P, Hopkins J, Harraway J, McLeod M, McLeod N, Harawira P, et al. E-cadherin germline mutations in familial gastric cancer. Nature. 1998;392:402-5.","DOI":"10.1038\/32918"},{"key":"5366_CR41","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1007\/s10120-013-0298-y","volume":"17","author":"M Yamada","year":"2014","unstructured":"Yamada M, Fukagawa T, Nakajima T, Asada K, Sekine S, Yamashita S, et al. Hereditary diffuse gastric cancer in a Japanese family with a large deletion involving CDH1. Gastric Cancer. 2014;17:750\u20136.","journal-title":"Gastric Cancer"},{"issue":"9","key":"5366_CR42","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1093\/hmg\/ddp046","volume":"18","author":"C Oliveira","year":"2009","unstructured":"Oliveira C, Senz J, Kaurah P, Pinheiro H, Sanges R, Haegert A, et al. Germline CDH1 deletions in hereditary diffuse gastric cancer families. Hum Mol Genet. 2009;18(9):1545\u201355.","journal-title":"Hum Mol Genet"},{"issue":"10","key":"5366_CR43","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1111\/j.1349-7006.2011.02038.x","volume":"102","author":"H Yamada","year":"2011","unstructured":"Yamada H, Shinmura K, Ito H, Kasami M, Sasaki N, Shima H, et al. Germline alterations in the CDH1 gene in familial gastric cancer in the Japanese population. Cancer Sci. 2011;102(10):1782.","journal-title":"Cancer Sci"},{"issue":"3","key":"5366_CR44","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1136\/gut.49.3.347","volume":"49","author":"Helicobacter and Cancer Collaborative Group","year":"2001","unstructured":"Helicobacter and Cancer Collaborative Group. Gastric cancer and helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut. 2001;49(3):347\u201353.","journal-title":"Gut"},{"issue":"6","key":"5366_CR45","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.bpg.2014.10.003","volume":"28","author":"R Herrero","year":"2014","unstructured":"Herrero R, Park JY, Forman D. The fight against gastric cancer, the IARC working group report. Best Pract Res Clin Gastroenterol. 2014;28(6):1107\u201314. \n                    https:\/\/doi.org\/10.1016\/j.bpg.2014.10.003\n                    \n                  .","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"5366_CR46","unstructured":"Choi IJ. The role of endoscopic screening in gastric cancer control in the Republic of Korea. In: IARC Helicobacter Pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. Lyon, France: International Agency for Research on Cancer (IARC Working Group Reports, 2014, No. 8) p. 16\u201320. Available from: \n                    http:\/\/publications.iarc.fr\/Book-And-Report-Series\/Iarc-Working-Group-Reports\/-Em-Helicobacter-Pylori-Em-Eradication-As-A-Strategy-For-Preventing-Gastric-Cancer-2014\n                    \n                  . Accessed 21 Feb 2019."},{"key":"5366_CR47","unstructured":"Asaka M. Strategy to eliminate gastric cancer deaths in Japan In: IARC Helicobacter Pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. Lyon, France: International Agency for Research on Cancer (IARC Working Group Reports, 2014 No.8) p. 21\u201327. Available from: \n                    http:\/\/publications.iarc.fr\/Book-And-Report-Series\/Iarc-Working-Group-Reports\/-Em-Helicobacter-Pylori-Em-Eradication-As-A-Strategy-For-Preventing-Gastric-Cancer-2014\n                    \n                  . Accessed 21 Feb 2019."},{"key":"5366_CR48","unstructured":"Lee YC. The regional status of current or planned gastric cancer prevention strategies in Taiwan, China In: IARC Helicobacter Pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. Lyon, France: International Agency for Research on Cancer (IARC Working Group Reports, 2014 No.8) p. 28\u201336. Available from: \n                    http:\/\/publications.iarc.fr\/Book-And-Report-Series\/Iarc-Working-Group-Reports\/-Em-Helicobacter-Pylori-Em-Eradication-As-A-Strategy-For-Preventing-Gastric-Cancer-2014\n                    \n                  . Accessed 21 Feb 2019."},{"key":"5366_CR49","unstructured":"Ferreccio C. The regional status of current or planned gastric cancer prevention strategies in Latin America In: IARC Helicobacter Pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. Lyon, France: International Agency for Research on Cancer (IARC Working Group Reports, 2014 No.8) p. 37\u201343. Available from: \n                    http:\/\/publications.iarc.fr\/Book-And-Report-Series\/Iarc-Working-Group-Reports\/-Em-Helicobacter-Pylori-Em-Eradication-As-A-Strategy-For-Preventing-Gastric-Cancer-2014\n                    \n                  . Accessed 21 Feb 2019."},{"key":"5366_CR50","unstructured":"Leja M. The regional status of current or planned gastric cancer prevention strategies in Europe In: IARC Helicobacter Pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. Lyon, France: International Agency for Research on Cancer (IARC Working Group Reports, 2014 No.8) p. 44\u201355. Available from: \n                    http:\/\/publications.iarc.fr\/Book-And-Report-Series\/Iarc-Working-Group-Reports\/-Em-Helicobacter-Pylori-Em-Eradication-As-A-Strategy-For-Preventing-Gastric-Cancer-2014\n                    \n                  . Accessed 21 Feb 2019."},{"key":"5366_CR51","unstructured":"Malekzadeh R. Effect of Helicobacter pylori eradication on different subtypes of gastric cancer: perspective from a Middle Eastern country In: IARC Helicobacter Pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. Lyon, France: International Agency for Research on Cancer (IARC Working Group Reports, 2014 No.8) p. 55\u201363. Available from: \n                    http:\/\/publications.iarc.fr\/Book-And-Report-Series\/Iarc-Working-Group-Reports\/-Em-Helicobacter-Pylori-Em-Eradication-As-A-Strategy-For-Preventing-Gastric-Cancer-2014\n                    \n                  . Accessed 21 Feb 2019."},{"issue":"5","key":"5366_CR52","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1093\/ije\/28.5.836","volume":"28","author":"JA Leeuwen Van","year":"1999","unstructured":"Van Leeuwen JA, Waltner-Toews D, Abernathy T, Smit B, Shoukri M. Associations between stomach cancer incidence and drinking water contamination with atrazine and nitrate in Ontario (Canada) agroecosystems, 1987-1991. Int J Epidemiol. 1999;28(5):836\u201340.","journal-title":"Int J Epidemiol"},{"key":"5366_CR53","unstructured":"Cremona in one day. In: Enrico Massetti E, editor. 2015 pp. 35\u201338. ISBN 978\u20131\u2013312-89500-3."}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12885-019-5366-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12885-019-5366-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12885-019-5366-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,7]],"date-time":"2020-03-07T00:08:51Z","timestamp":1583539731000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/s12885-019-5366-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,8]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["5366"],"URL":"https:\/\/doi.org\/10.1186\/s12885-019-5366-1","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,8]]},"assertion":[{"value":"30 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"BMD is a PhD Medical Biotechnologist who started to collect the data of this registry in 2012 as Clinical Study Coordinator in an Oncology department. Later she specialized in Health Biometry and as Biostatistician, she sought to make sense of this collection of data, with the ambitious aim of contributing to the characterization of Gastric Cancer patients who are inhabitants of an Italian area characterized by a high incidence of this pathology, in order to focus attention on prevention.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 information"}},{"value":"Italian legislation identifies cancer registries as collectors of personal data for surveillance purposes without explicit individual consent. The approval of a research ethics committee is not required, since this study is a descriptive study without any direct or indirect intervention on patients (DM n.17A03142 3\/3\/17 GU n.109 5\/12\/17\u2033 (available at: \/ eli\/id\/2017\/05\/12\/17A03142\/sg, latest access on 7\/16\/18).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"212"}}