{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:55:47Z","timestamp":1791291347199,"version":"4.3.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>A few studies regarding the epidemiology and risk factors of Non-muscle Invasive Bladder Cancer (NMIBC) are reported from Sub-Saharan African countries (SSA), including Somalia, and the African literature is scant on the management of NMIBC. The present study aims to evaluate the clinical-histopathological characteristics and factors associated with the survival rate of patients with NMIBC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This six-year cohort study included 196 patients with NMIBC. It reviewed the clinical and histopathological characteristics and factors predicting cancer-specific survival for these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean patient age was 59.01\u2009\u00b1\u200911.50 years, with a male-to-female ratio of 2.8:1. Urothelial carcinoma (UC) constituted the most common pathological type, accounting for 90.8%; Ta LG and T1HG were the most common histopathological tumour stage and grade (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200990, 45.9%, vs.\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200956, 28.6%), respectively. The mean tumour size was 4.72\u2009\u00b1\u20092.81\u00a0cm. The cancer-specific mortality(CSM) was 13.3%. Age [2.252(2.310\u20132.943],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001], Gender [1.031(0.981-1.1.242),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001], tumour stage and grade [4.902(3.607\u20135.614),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001], tumour location [1.135(0.806\u20131.172),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001], number [0.510(0.410\u20130.920),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03], tumour size [1.523(0.936\u20131.541),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001], use of intravesical chemotherapy or BCG [2.810(1.972\u20134.381),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001], preoperative hydronephrosis grade [1.517(1.172\u20132.154),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001], and follow-up compliance [3.376(2.633\u20135.018),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001] were all associated with CSM. The 5-year overall survival was 57.1%, and cardiovascular diseases were the leading cause of mortality (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200934), followed by diabetes (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200928).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study findings revealed that UC constituted the most common pathological subtype, though less than forty per cent of our patients receive intravesical adjuvant therapies, which are crucial to minimizing disease morbidity and mortality. Initiatives improving uro-oncological care, including subspecialty training in oncology and essential cancer therapies, better access to urology services, and cancer screening programs, are much needed for optimal management plans and care in the country.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12885-024-12632-9","type":"journal-article","created":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T05:01:32Z","timestamp":1720933292000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical characteristics and factors associated with survival rate of patients with non-muscle invasive bladder cancer attending at a Tertiary Hospital in Somalia"],"prefix":"10.1186","volume":"24","author":[{"given":"Abdikarim Hussein","family":"Mohamed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled Ali","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ertan","family":"Kayacan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yassin","family":"Nur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Abdikarim","family":"Nur-amin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,14]]},"reference":[{"issue":"6","key":"12632_CR1","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/j.eururo.2020.09.006","volume":"78","author":"JYC Teoh","year":"2020","unstructured":"Teoh JYC, Huang J, Ko WYK, Lok V, Choi P, Ng CF, et al. 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