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Spectral-Domain Optical Coherence Tomography (SD-OCT) was used to evaluate the macula, the RNFL, the GCL, and the CT. Measurements were taken in the follicular phase (day 3) of the last menstrual cycle in all women. The body mass index (BMI) scores of all participants were also recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No disparity in terms of age and BMI between both groups was observed (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.444,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.074, respectively)\n                      <jats:italic>.<\/jats:italic>\n                      All the macular parameters measurements were considerably lower in the OCP group compared to the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Also, the RNFL thickness, the GCL thickness, and the CT were all significantly thinner in the OCP group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of OCP can cause significant changes in the retina and choroid thickness over 1 year period. The women who are using OCP for a longer duration could have some eye problems. OCT should be routinely done for follow up. Further long term studies are required, using different preparations of OCP. It is important to find out when this thickness alterations can be clinically significant or symptomatic and if these changes are reversible or not.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12886-019-1263-2","type":"journal-article","created":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T09:05:04Z","timestamp":1575968704000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["The effect of oral contraceptive pills on the macula, the retinal nerve fiber layer, the ganglion cell layer and the choroidal thickness"],"prefix":"10.1186","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5337-4709","authenticated-orcid":false,"given":"Yasmine Maher","family":"Shaaban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5726-7775","authenticated-orcid":false,"given":"Tamer Abdel Fattah","family":"Badran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,10]]},"reference":[{"key":"1263_CR1","first-page":"1604","volume":"10","author":"MM Moschos","year":"2017","unstructured":"Moschos MM, Nitoda E. 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The ESC Ethics Committee approved the use of verbal-only consent to participate in the study because (1) All the data in the study were collected through performing Spectral-Domain Optical Coherence Tomography (SD-OCT), which is a noninvasive imaging technique used for medical imaging, employed in clinical practice and does not require written consent, it uses light waves to take cross-section pictures of the retina). (2) The procedure was performed with no sedation or anesthesia, and no topical eye drops were instilled for corneal anesthesia or dilatation of the pupil before the test. (3) The possibility of discomfort expected in the study is not greater than those ordinarily happened during the performance of the routine ocular examination. For obtaining the informed verbal consent, the investigator reads and explains a verbal version of consent from an information sheet which includes most of the elements of a consent form (purpose, the procedure, and its duration, any risk of discomfort, benefits, the confidentiality of records, etc). All subjects were allowed to ask questions before giving their verbal consent.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"250"}}