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The mean pupil power (MPP) and corneal morphology parameters were also measured. Correlations between ACD and curvature and morphology parameters were analyzed by linear regression.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>172 eyes of 86 patients (9 to 45 years) were classified into the VAE-N (<jats:italic>n<\/jats:italic>\u2009=\u200986) group and the VAE-E group (<jats:italic>n<\/jats:italic>\u2009=\u200986) based on the corneal morphology. The central (3.32\u2009\u00b1\u20090.27\u00a0mm versus 3.43\u2009\u00b1\u20090.29\u00a0mm, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and paracentral ACDs increased significantly in the VAE-E group, and the corneal morphology parameters were also significantly higher. The central ACD was significantly correlated with the MPP (<jats:italic>r<\/jats:italic>\u2009=\u20090.465), KVf\/b (Keratoconus Vertex front\/back) (<jats:italic>r<\/jats:italic>\u2009=\u20090.306, <jats:italic>r<\/jats:italic>\u2009=\u20090.327), and BCVf\/b (Baiocchi Calossi Versaci front\/back) (<jats:italic>r<\/jats:italic>\u2009=\u20090.356, <jats:italic>r<\/jats:italic>\u2009=\u20090.416). Linear regression showed good relationships between \u25b3ACD and \u25b3MPP (R<jats:sup>2<\/jats:sup>\u2009=\u20090.429) and \u25b3KVf\/b (R<jats:sup>2<\/jats:sup>\u2009=\u20090.504, R<jats:sup>2<\/jats:sup>\u2009=\u20090.536).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The ACD was larger in the VAE-E group. The difference in ACD between the VAE-E and VAE-N groups was significantly correlated with corneal curvature and the extent of corneal elevation, indicating the influences of both the corneal magnification effect and corneal ectasia on ACD.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12886-024-03353-5","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T13:02:22Z","timestamp":1708952542000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Differences in anterior chamber depth in keratoconus patients with binocular very asymmetry ectasia"],"prefix":"10.1186","volume":"24","author":[{"given":"Zizhen","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haowen","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueguo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"issue":"4","key":"3353_CR1","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","volume":"42","author":"YS Rabinowitz","year":"1998","unstructured":"Rabinowitz YS, Keratoconus. 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