{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T02:04:52Z","timestamp":1789524292937,"version":"build-2803163510"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Ophthalmol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Ectopia lentis is the dislocation of the natural crystalline lens and usually presents in the setting of trauma or other systemic diseases. Herein, we describe a case of an otherwise healthy four-year-old boy with isolated ectopia lentis whose partial lens dislocation was captured on a smartphone by the patient\u2019s father several days prior.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A four-year-old boy with no past medical, developmental, or trauma history presented with bilateral partial anterior lens dislocation with pupillary block. Initial ophthalmic evaluation two months prior was notable for uncorrected visual acuity at 20\/100 OD, 20\/250 OS, bilateral iridodenesis, and partially dislocated lenses inferonasally OD and inferiorly OS on slit lamp. Genetic testing found no abnormalities. Ten months later, the patient developed sudden onset of left eye pain. A dislocated lens and temporarily dilated left pupil were captured on a smartphone by the patient\u2019s father. He was evaluated 3 days later after a second episode and found to have hand motion vision OS, a fixed 8\u00a0mm left pupil with the crystalline lens subluxed into the pupil space and accompanying intraocular pressure OS of 40 mmHg. The lens was surgically removed with a limited anterior vitrectomy. Four and a half years after surgery, visual acuity was 20\/125 OS with aphakic correction. The right eye eventually underwent prophylactic lensectomy and was 20\/30 in aphakic correction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This report presents a unique presentation of isolated ectopia lentis with anterior lens dislocation and pupillary block and illustrates the role of smartphone photography in assisting in the triage of eye emergencies.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12886-024-03455-0","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T10:02:19Z","timestamp":1714039339000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Isolated ectopia lentis with partial anterior dislocation and pupillary block: a case report"],"prefix":"10.1186","volume":"24","author":[{"given":"Ariel","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela M.","family":"Ngo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael X.","family":"Repka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney L.","family":"Kraus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"3455_CR1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3109\/08820538.2013.825276","volume":"28","author":"MA Sadiq","year":"2013","unstructured":"Sadiq MA, Vanderveen D. Genetics of Ectopia Lentis. Semin Ophthalmol. 2013;28:5\u20136.","journal-title":"Semin Ophthalmol"},{"key":"3455_CR2","doi-asserted-by":"crossref","unstructured":"Esfandiari H, Ansari S, Mohammad-Rabei H, Mets M. Management strategies of ocular abnormalities in patients with marfan syndrome: current perspective. J Ophthalmic Vis Res. 2019;14(1).","DOI":"10.4103\/jovr.jovr_29_18"},{"key":"3455_CR3","doi-asserted-by":"crossref","unstructured":"Neuhann TM, Stegerer A, Riess A, Blair E, Martin T, Wieser S et al. ADAMTSL4-associated isolated ectopia lentis: further patients, novel mutations and a detailed phenotype description. Am J Med Genet A. 2015;167(10).","DOI":"10.1002\/ajmg.a.37157"},{"key":"3455_CR4","doi-asserted-by":"crossref","unstructured":"Chandra A, Aragon-Martin JA, Hughes K, Gati S, Ashwin Reddy M, Deshpande C et al. A genotype-phenotype comparison of ADAMTSL4 and FBN1 in isolated ectopia lentis. Invest Ophthalmol Vis Sci. 2012;53(8).","DOI":"10.1167\/iovs.12-9874"},{"key":"3455_CR5","doi-asserted-by":"crossref","unstructured":"Kim YJ, Ha SJ. Intracapsular lens extraction for the treatment of pupillary block glaucoma associated with anterior subluxation of the crystalline lens. Case Rep Ophthalmol. 2013;4(3).","DOI":"10.1159\/000356530"},{"key":"3455_CR6","doi-asserted-by":"crossref","unstructured":"Choi DY, Kim JG, Song BJ. Surgical management of crystalline lens dislocation into the anterior chamber with corneal touch and secondary glaucoma. J Cataract Refract Surg. 2004;30(3).","DOI":"10.1016\/j.jcrs.2003.07.012"},{"key":"3455_CR7","doi-asserted-by":"crossref","unstructured":"Garza-Leon M, De La Parra-Col\u00edn P. Medical treatment of crystalline lens dislocation into the anterior chamber in a patient with Marfan syndrome. Int Ophthalmol. 2012;32(6).","DOI":"10.1007\/s10792-012-9592-7"},{"key":"3455_CR8","doi-asserted-by":"crossref","unstructured":"Kawashima M, Kawakita T, Shimazaki J. Complete spontaneous crystalline lens dislocation into the anterior chamber with severe corneal endothelial cell loss. Cornea. 2007;26(4).","DOI":"10.1097\/ICO.0b013e3180303ae7"},{"key":"3455_CR9","doi-asserted-by":"crossref","unstructured":"Kwon YA, Bae SH, Sohn YH. Bilateral spontaneous anterior lens dislocation in a retinitis pigmentosa patient. Korean J Ophthalmol. 2007;21(2).","DOI":"10.3341\/kjo.2007.21.2.124"},{"key":"3455_CR10","doi-asserted-by":"crossref","unstructured":"Seong M, Kim MJ, Tchah H. Argon laser iridotomy as a possible cause of anterior dislocation of a crystalline lens. J Cataract Refract Surg. 2009;35(1).","DOI":"10.1016\/j.jcrs.2008.07.035"},{"key":"3455_CR11","doi-asserted-by":"crossref","unstructured":"Vasavada AR, Praveen MR, Desai C. Management of bilateral anterior dislocation of a lens in a child with Marfan\u2019s syndrome. J Cataract Refract Surg. 2003;29(3).","DOI":"10.1016\/S0886-3350(02)01529-8"},{"key":"3455_CR12","doi-asserted-by":"crossref","unstructured":"Mukhopadhyay U, Chakrabort C, Mondal A, Pattyanayak U, Agarwal R, Tripathi P. Spontaneous dislocation of a crystalline lens to the anterior chamber with pupillary block glaucoma in Noonan Syndrome: a case report. Pan Afr Med J. 2014;17.","DOI":"10.11604\/pamj.2014.17.135.3049"}],"container-title":["BMC Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12886-024-03455-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12886-024-03455-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12886-024-03455-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T10:10:25Z","timestamp":1714039825000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcophthalmol.biomedcentral.com\/articles\/10.1186\/s12886-024-03455-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,25]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3455"],"URL":"https:\/\/doi.org\/10.1186\/s12886-024-03455-0","relation":{},"ISSN":["1471-2415"],"issn-type":[{"value":"1471-2415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,25]]},"assertion":[{"value":"17 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written consent was obtained from the parent of the patient to publish the medical information and related images in this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"192"}}