{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T14:17:38Z","timestamp":1775571458905,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":36,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Ophthalmol"],"DOI":"10.1186\/s12886-026-04697-w","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T04:08:20Z","timestamp":1772424500000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Correlation between mid-term intraocular pressure and aqueous flare value in micropulse transscleral cyclophotocoagulation: a retrospective observational study"],"prefix":"10.1186","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8560-9901","authenticated-orcid":false,"given":"Mitsuya","family":"Otsuka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaku","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruhiko","family":"Hamanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Akai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhito","family":"Nitta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"issue":"2","key":"4697_CR1","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1007\/s40123-024-01080-0","volume":"14","author":"RMPC de Crom","year":"2025","unstructured":"de Crom RMPC, Kujovic-Aleksov S, Webers CAB, Berendschot TTJM, Beckers HJM. Long-term treatment outcomes of micropulse transscleral cyclophotocoagulation in primary and secondary glaucoma: a 5-year analysis. Ophthalmol Ther. 2025;14(2):323\u201335. https:\/\/doi.org\/10.1007\/s40123-024-01080-0.","journal-title":"Ophthalmol Ther"},{"issue":"6","key":"4697_CR2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1167\/iovs.63.6.3","volume":"63","author":"H Nemoto","year":"2022","unstructured":"Nemoto H, Honjo M, Okamoto M, Sugimoto K, Aihara M. Potential mechanisms of intraocular pressure reduction by micropulse transscleral cyclophotocoagulation in rabbit eyes. Invest Ophthalmol Vis Sci. 2022;63(6):3. https:\/\/doi.org\/10.1167\/iovs.63.6.3.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"4697_CR3","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1159\/000510596","volume":"65","author":"T Tsujisawa","year":"2022","unstructured":"Tsujisawa T, Ishikawa H, Uga S, Asakawa K, Kono Y, Mashimo K, Shoji N. Morphological changes and potential mechanisms of intraocular pressure reduction after micropulse transscleral cyclophotocoagulation in rabbits. Ophthalmic Res. 2022;65(5):595\u2013602. https:\/\/doi.org\/10.1159\/000510596.","journal-title":"Ophthalmic Res"},{"issue":"1","key":"4697_CR4","doi-asserted-by":"publisher","first-page":"26","DOI":"10.14744\/bej.2022.13471","volume":"8","author":"BK Atik","year":"2023","unstructured":"Atik BK, Altan C, Pehlivanoglu S, Ahmet S. Aqueous flare and intraocular pressure in the early period following panretinal photocoagulation in patients with proliferative diabetic retinopathy. Beyoglu Eye J. 2023;8(1):26\u201331. https:\/\/doi.org\/10.14744\/bej.2022.13471.","journal-title":"Beyoglu Eye J"},{"key":"4697_CR5","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1186\/s12886-021-02012-3","volume":"21","author":"A Kimura","year":"2021","unstructured":"Kimura A, Nakashima KI, Inoue T. Correlation between intraocular pressure reduction and anterior chamber aqueous flare after micropulse transscleral cyclophotocoagulation. BMC Ophthalmol. 2021;21:266. https:\/\/doi.org\/10.1186\/s12886-021-02012-3.","journal-title":"BMC Ophthalmol"},{"issue":"3","key":"4697_CR6","doi-asserted-by":"publisher","first-page":"408","DOI":"10.18502\/jovr.v15i3.7459","volume":"15","author":"F Ghassemi","year":"2020","unstructured":"Ghassemi F, Niyousha MR, Hassanpoor N, Khojasteh H. Uveitis-induced refractory ocular hypotony managed with high-dose latanoprost. J Ophthalmic Vis Res. 2020;15(3):408\u201311. https:\/\/doi.org\/10.18502\/jovr.v15i3.7459.","journal-title":"J Ophthalmic Vis Res"},{"issue":"3","key":"4697_CR7","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1080\/09273948.2019.1668952","volume":"29","author":"A Marchese","year":"2021","unstructured":"Marchese A, Giuffr\u00e8 C, Miserocchi E, Cicinelli MV, Bandello F, Modorati G. Severe hypotony maculopathy in anterior uveitis associated with Hodgkin lymphoma. Ocul Immunol Inflamm. 2021;29(3):460\u20134. https:\/\/doi.org\/10.1080\/09273948.2019.1668952.","journal-title":"Ocul Immunol Inflamm"},{"issue":"2","key":"4697_CR8","doi-asserted-by":"publisher","first-page":"104","DOI":"10.3109\/09273948.2011.647228","volume":"20","author":"HN Sen","year":"2012","unstructured":"Sen HN, Drye LT, Goldstein DA, Larson TA, Merrill PT, Pavan PR, et al. Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Hypotony in patients with uveitis: the Multicenter Uveitis Steroid Treatment (MUST) Trial. Ocul Immunol Inflamm. 2012;20(2):104\u201312. https:\/\/doi.org\/10.3109\/09273948.2011.647228.","journal-title":"Ocul Immunol Inflamm"},{"issue":"11","key":"4697_CR9","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1016\/j.ophtha.2012.05.032","volume":"119","author":"E Daniel","year":"2012","unstructured":"Daniel E, Pistilli M, Pujari SS, Ka\u00e7maz RO, Nussenblatt RB, Rosenbaum JT, et al. Risk of hypotony in noninfectious uveitis. Ophthalmology. 2012;119(11):2377\u201385. https:\/\/doi.org\/10.1016\/j.ophtha.2012.05.032.","journal-title":"Ophthalmology"},{"key":"4697_CR10","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.ajo.2016.06.026","volume":"169","author":"A Moradi","year":"2016","unstructured":"Moradi A, Stroh IG, Reddy AK, Hornbeak DM, Leung TG, Burkholder BM, Thorne JE. Risk of hypotony in juvenile idiopathic arthritis-associated uveitis. Am J Ophthalmol. 2016;169:113\u201324. https:\/\/doi.org\/10.1016\/j.ajo.2016.06.026.","journal-title":"Am J Ophthalmol"},{"issue":"12","key":"4697_CR11","first-page":"717","volume":"108","author":"S Okisaka","year":"2004","unstructured":"Okisaka S. Variation of inflammatory reaction of ciliary body\u2014harmony between clinic and basic science. Nippon Ganka Gakkai zasshi. 2004;108(12):717\u201348. Japanese.","journal-title":"Nippon Ganka Gakkai zasshi"},{"issue":"3","key":"4697_CR12","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/s10792-011-9440-1","volume":"31","author":"C Heinz","year":"2011","unstructured":"Heinz C, Zurek-Imhoff B, Koch J, R\u00f6sel M, Heiligenhaus A. Long-term reduction of laser flare values after trabeculectomy but not after cyclodestructive procedures in uveitis patients. Int Ophthalmol. 2011;31(3):205\u201310. https:\/\/doi.org\/10.1007\/s10792-011-9440-1.","journal-title":"Int Ophthalmol"},{"issue":"3","key":"4697_CR13","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/bmt.2012.244","volume":"48","author":"Y Kanda","year":"2013","unstructured":"Kanda Y. Investigation of the freely available easy-to-use software EZR for medical statistics. Bone Marrow Transpl. 2013;48(3):452\u20138. https:\/\/doi.org\/10.1038\/bmt.2012.244.","journal-title":"Bone Marrow Transpl"},{"issue":"10","key":"4697_CR14","first-page":"1231","volume":"25","author":"JE Pederson","year":"1984","unstructured":"Pederson JE. Outflow facility in acute experimental ciliochoroidal detachment. Invest Ophthalmol Vis Sci. 1984;25(10):1231\u20132.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"4697_CR15","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3341\/kjo.1989.3.2.65","volume":"3","author":"SH Joo","year":"1989","unstructured":"Joo SH, Ko MK, Choe JK. Outflow of aqueous humor following cyclodialysis or ciliochoroidal detachment in rabbits. Korean J Ophthalmol. 1989;3(2):65\u20139. https:\/\/doi.org\/10.3341\/kjo.1989.3.2.65.","journal-title":"Korean J Ophthalmol"}],"container-title":["BMC Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12886-026-04697-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12886-026-04697-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12886-026-04697-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T13:37:03Z","timestamp":1775569023000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12886-026-04697-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,2]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4697"],"URL":"https:\/\/doi.org\/10.1186\/s12886-026-04697-w","relation":{},"ISSN":["1471-2415"],"issn-type":[{"value":"1471-2415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,2]]},"assertion":[{"value":"11 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This retrospective observational study adhered to the tenets of the Declaration of Helsinki and was approved by the institutional review board of our hospital (approval number: R2025063). The study was approved by the Research Ethics Office for Human Subjects, University of Toyama. Informed consent to participate was obtained from all of the participants in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"167"}}