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The survival rate of MP has increased up to 80% in recent years. According to. a review of the treatment and outcomes of patients diagnosed with MP, we evaluated the influence of. early operation on survival rate and discussed the risk factors of prognosis.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>We collected 79 cases of patients diagnosed with MP who were treated in our department. from October 2001 to December 2017. They were divided into 2 groups. Patients in group A were born. in our hospital. Patients in group B were born in a local hospital with suspicion of MP and then transferred. to our department.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The birth weight (BW) and gestational age (GA) of patients were higher in group A than in. group B. There was no significant difference in the proportion of premature and low birth weight (LBW). patients between the two groups (<jats:italic>p\u2009=<\/jats:italic>\u00a00.422, <jats:italic>p\u2009=<\/jats:italic>\u00a00.970). Their age at the time of surgery was younger in. group A than in group B (1.4\u2009\u00b1\u20092.0 vs. 6.9\u2009\u00b1\u200914.9, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The overall survival rate of group A was higher. than that of group B (95.0% vs. 79.5%, <jats:italic>p\u2009=<\/jats:italic>\u00a00.038). The prognosis of premature patients was worse than. that of full-term infants for both groups (<jats:italic>p\u2009=<\/jats:italic>\u00a00.012).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Prematurity is a significant risk factor related to death for MP patients. The survival rate. of MP patients can be improved by early operation during the neonatal period.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12887-019-1844-5","type":"journal-article","created":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T09:46:52Z","timestamp":1576489612000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Can early surgery improve the outcome of patients with meconium peritonitis? 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All procedures were in accordance with the ethical standards of \u201cEthics Committee of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine\u201d and with the Declaration of Helsinki.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"473"}}