{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T17:08:41Z","timestamp":1774890521974,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>The peritonitis rate among children treated with peritoneal dialysis (PD) has not been widely reported in Saudi Arabia. The study aim was to estimate the peritonitis rate per patient-year and investigate the factors associated with higher peritonitis rates in a sample of PD children at King Abdullah Specialist Children\u2019s Hospital-Riyadh (KASCH-R), Saudi Arabia.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>This retrospective cohort study included 27 PD children treated between September 2007 and December 2017 at KASCH-R. We recorded the children\u2019s demographic and clinical data, and the frequency of peritonitis.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The 27 PD children reviewed (63% girls; mean age\u2009=\u20097.32\u2009years old; range, 1\u201314\u2009years), resulted in 86 peritonitis diagnoses in which the overall recurrence rate (in at least one episode) was 58\/86 (67.4%) with a 95% confidence interval (CI), 56.5 to 77.2%. The rate of peritonitis episodes per patient-year was 0.76 (1 episode per 1.31 patient-year). The generalized Poisson model identified older children (age\u2009&gt;\u2009\u00a010\u2009years) (adjusted rate ratios [aRR]\u2009=\u20097.273, 95% CI: 1.562\u201333.860), congenital nephrosis (aRR\u2009=\u20094.677, 95% CI: 1.443\u201315.155), height below 3rd percentile (aRR\u2009=\u20094.689, 95% CI: 1.874\u201311.735), weight below 3rd percentile (aRR\u2009=\u20095.388, 95% CI: 1.678\u201317.302), low albumin level (aRR\u2009=\u20094.041, 95% CI: 2.053\u20137.956), two-week duration of antibiotic therapy (aRR\u2009=\u20092.947, 95% CI: 1.163\u20137.468), which were independently associated with a high peritonitis rate.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>This study showed a high peritonitis rate in our center. Older children, congenital nephrosis, height and weight below the 3rd percentile, low albumin level, and long duration of antibiotic therapy were associated with a higher rate of peritonitis. An optimal peritonitis prevention strategy or best-practice guideline is needed to reduce and prevent peritonitis occurrence in our center.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12887-020-1936-2","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T10:03:06Z","timestamp":1580292186000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Factors influencing occurrence of peritonitis in Saudi children on peritoneal dialysis"],"prefix":"10.1186","volume":"20","author":[{"given":"Khamisa","family":"Al Mokali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Al Sannaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faten","family":"Al Mutairi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8743-6007","authenticated-orcid":false,"given":"Anwar E.","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,1,29]]},"reference":[{"issue":"1\u20133","key":"1936_CR1","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1159\/000484344","volume":"45","author":"D Ponce","year":"2018","unstructured":"Ponce D, de Moraes TP, Pecoits-Filho R, Figueiredo AE, Barretti P. 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This study has been completed prior to Dr. Anwar Ahmed joining the Uniformed Services University of the Health Sciences and Henry M Jackson Foundation for the Advancement of Military Medicine.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"42"}}