{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:11:44Z","timestamp":1789611104728,"version":"build-2803163510"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                <jats:title>Abstract<\/jats:title>\n                <jats:p>Early discharge of preterm very low birth weight (VLBW) infants is at times inevitable in low resource settings. The implication of such practice on the growth of this high-risk population is not known. We conducted a retrospective chart review to describe the growth of preterm VLBW infants discharged with a weight of less than 1500\u2009g.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>To describe the growth of discharged preterm VLBW infants over the first 12\u2009weeks.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Method<\/jats:title>\n                <jats:p>Between June 2013 and January 2014; 164 discharged preterm VLBW infants were followed up for 3\u2009months. Among the survivors (132), we identified 111 infant records for this study. Relevant data was entered in STATA for analysis. Growth percentiles were determined at approximately 4\u2009weeks, 8\u2009weeks, and 12\u2009weeks post-discharge using the intergrowth 21st growth charts. Growth velocities were computed using the 2-point average weight model. Regression analysis was used to identify factors associated with growth failure. Growth failure was defined as occipital frontal circumference (OFC), weight, and length\u2009&lt;\u200910th centile by 12\u2009weeks post-discharge. <jats:italic>P<\/jats:italic>-value of &lt;\u20090.05 was considered significant at a 95% confidence interval.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among the study infants the median gestational age and weight at birth were 32\u2009weeks (range 28-35\u2009weeks) and 1250\u2009g(range 850-1500\u2009g) respectively; 60\/111(54%) were Small for Gestational Age (SGA). The median discharge postmenstrual age (PMA) was 34\u2009weeks (range 30-38\u2009weeks) and weight was 1140\u2009g (range 830-1490\u2009g). The majority 88.2% had not recovered birth weight at discharge of whom 59.1% recovered by 2\u2009weeks and 40.9% recovered between 2 and 4\u2009weeks after discharge. By 12\u2009weeks post-discharge the median PMA and weight were 46\u2009weeks (range 37-51\u2009weeks),and 3110\u2009g (range 1750-5000\u2009g) respectively, 38.7% of the infants had growth failure and 36.9% had OFC &lt;3rd centile. Growth velocity\u2009&lt;\u200915\u2009g\/kg\/d in the first 4\u2009weeks (OR 3.8, p 0.010) and subsequent 4\u2009weeks (OR 2.5, p 0.049) post-discharge were independently associated with growth failure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Slow birth weight recovery was observed and growth failure was prevalent by 12\u2009weeks post-discharge with more than a third having severe microcephaly. Poor post-discharge growth velocity was associated with subsequent growth failure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Recommendations<\/jats:title>\n                <jats:p>Growth velocity monitoring among preterm VLBW infants should be emphasized. The implication and interventions of this early growth failure needs to be explored.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12887-021-02612-4","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T06:03:19Z","timestamp":1616652199000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Growth of preterm very low birth weight infants discharged with weight of less than 1500grams"],"prefix":"10.1186","volume":"21","author":[{"given":"Yaser","family":"Abdallah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Namiiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolly","family":"Nankunda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamiru","family":"Mugalu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Vaucher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"key":"2612_CR1","doi-asserted-by":"crossref","unstructured":"Blencowe H, Krasevec J, de Onis M, et al. 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Written informed consent was obtained from all the parents of the study infants. All study procedures were performed according to approved protocol and the units\u2019 daily procedures.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"This was obtained from the parents of study infants and from the Uganda National Counsel of Science and Technology.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None of the authors have any competing interest to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"145"}}