{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:43:56Z","timestamp":1782953036078,"version":"3.54.5"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T00:00:00Z","timestamp":1641168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T00:00:00Z","timestamp":1641168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004761","name":"Natural science foundation of Hunan province China","doi-asserted-by":"crossref","award":["2019JJ50324"],"award-info":[{"award-number":["2019JJ50324"]}],"id":[{"id":"10.13039\/501100004761","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Backgroud<\/jats:title>\n                <jats:p>Synovial chondromatosis is a rare synovial-derived metaplasia disease that comes from the formation of cartilage nodules within the synovial connective tissue of the joint. Knee tuberculosis is a disease caused mostly by the pulmonary tuberculosis and a few by tuberculosis of the digestive tract and lymphatic.<\/jats:p>\n                <jats:p>tube.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>Herein we report a 3-year-old child admitted by intermittent swelling of left knee joint with lameness for half a year, the patient received surgical treatment. The loose bodies filled in the joint cavity was taken out and the degenerative synovium was excised. Biopsy confirmed as synovial chondromatosis combined with synovial tuberculosis of knee joint. After 6\u2009months follow-ups, knee swelling and claudication get totally recovered and the gait of patient recover back to normal.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Careful investigation of children with knee pain is recommended to avoid misdiagnosis, Synovial chondromatosis combine with tuberculosis should be considered a differential diagnosis in a child with knee pain.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12887-021-03085-1","type":"journal-article","created":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T07:03:20Z","timestamp":1641193400000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Synovial chondromatosis combine with synovial tuberculosis of knee joint: a case report"],"prefix":"10.1186","volume":"22","author":[{"given":"Nan","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djandan Tadum","family":"Arthur V","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runbin","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,3]]},"reference":[{"issue":"6","key":"3085_CR1","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.reuma.2013.12.008","volume":"10","author":"A Jimenez Martin","year":"2014","unstructured":"Jimenez Martin A, Zurera Carmona M, Santos Yubero FJ, Perez-Hidalgo S. Arthroscopic treatment of synovial chondromatosis, an unusual cause of shoulder pain. Reumatol Clin. 2014;10(6):416\u20137.","journal-title":"Reumatol Clin"},{"issue":"4","key":"3085_CR2","first-page":"294","volume":"7","author":"D Villafuerte Delgado","year":"2017","unstructured":"Villafuerte Delgado D, Heras Heras MG, Gonz\u00e1lez PF. Osteocondromatosis sinovial : a prop\u00f3sito de un caso. Rev Finlay. 2017;7(4):294\u20139.","journal-title":"Rev Finlay"},{"issue":"1","key":"3085_CR3","first-page":"29","volume":"44","author":"KS Kant","year":"2014","unstructured":"Kant KS, Agarwal A, Suri T, Gupta N, Verma I, Shaharyar A. Tuberculosis of knee region in children: a series of eight cases. Trop Dr. 2014;44(1):29\u201332.","journal-title":"Trop Dr"},{"issue":"3","key":"3085_CR4","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1093\/tropej\/50.3.182","volume":"50","author":"M Uzel","year":"2004","unstructured":"Uzel M, Garipardic M, Cetinus E, Bilgic E, Karaoguz A, Boran C, et al. Tuberculosis of the knee in a child. J Trop Pediatr. 2004;50(3):182\u20134.","journal-title":"J Trop Pediatr"},{"issue":"3","key":"3085_CR5","first-page":"e71","volume":"6","author":"EF Temponi","year":"2016","unstructured":"Temponi EF, Mortati RB, Mortati GMH, Mortati LB, Sonnery-Cottet B, de Carvalho J\u00fanior LH. Synovial Chondromatosis of the knee in a 2-year-old child: a case report and review of the literature. JBJS case. Connect. 2016;6(3):e71.","journal-title":"Connect."},{"issue":"4","key":"3085_CR6","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1093\/jhps\/hny034","volume":"5","author":"B Efrima","year":"2018","unstructured":"Efrima B, Safran N, Amar E, Bachar Avnieli I, Kollander Y, Rath E. Simultaneous pigmented villonodular synovitis and synovial chondromatosis of the hip: case report. J Hip Preserv Surg. 2018;5(4):443\u20137.","journal-title":"J Hip Preserv Surg"},{"issue":"1","key":"3085_CR7","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/0266-7681_87_90048-9","volume":"12","author":"JR Jones","year":"1987","unstructured":"Jones JR, Evans DM, Kaushik A. Synovial chondromatosis presenting with peripheral nerve compression--a report of two cases. J Hand Surg Br. 1987;12(1):25\u20137.","journal-title":"J Hand Surg Br"},{"issue":"11","key":"3085_CR8","doi-asserted-by":"publisher","first-page":"404","DOI":"10.5312\/wjo.v10.i11.404","volume":"10","author":"L Monestier","year":"2019","unstructured":"Monestier L, Riva G, Stissi P, Latiff M, Surace MF. Synovial chondromatosis of the foot: two case reports and literature review. World J Orthop. 2019;10(11):404\u201315.","journal-title":"World J Orthop"}],"container-title":["BMC Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12887-021-03085-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12887-021-03085-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12887-021-03085-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T19:05:03Z","timestamp":1641236703000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpediatr.biomedcentral.com\/articles\/10.1186\/s12887-021-03085-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,3]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["3085"],"URL":"https:\/\/doi.org\/10.1186\/s12887-021-03085-1","relation":{},"ISSN":["1471-2431"],"issn-type":[{"value":"1471-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,3]]},"assertion":[{"value":"1 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the ethic committee of Hunan Provincial People\u2019s Hospital, the First Affiliated Hospital of Hunan Normal University. Written informed consent was obtained from individual or guardian participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Parents\/guardians gave their written consent for their child\u2019s personal or clinical details along with all identifying images to be published in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing financial interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"8"}}