{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:17:24Z","timestamp":1791346644832,"version":"4.3.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T00:00:00Z","timestamp":1645142400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T00:00:00Z","timestamp":1645142400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"the project of invigorating healthcare through science, technology and education","award":["KJXW 2018020"],"award-info":[{"award-number":["KJXW 2018020"]}]},{"name":"the project of invigorating healthcare through science, technology and education","award":["KJXW 2019018"],"award-info":[{"award-number":["KJXW 2019018"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Short stature is defined as height below 2 standard deviations of the population with the same age, gender. This study is aimed to assess the characteristics of body composition in preschool children with short stature.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Anthropometric measurements and body composition were assessed in 68 preschool children aged 3 to 6\u2009years old with short stature and 68 normal controls matched on age and gender. Height, weight and body composition (total body water, protein, minerals, body fat mass, fat-free mass, soft lean mass, skeletal muscle mass, and bone mineral contents) in the two groups were measured and compared.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The total body water, protein, minerals, body fat mass, fat-free mass, soft lean mass, skeletal muscle mass, and bone mineral contents were lower in preschool children with short stature than controls (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Body mass index and fat mass index did not differ between groups. Fat-free mass index was significantly lower in short stature group than controls (t\u2009=\u20092.17, <jats:italic>P<\/jats:italic>\u2009=\u20090.03). Linear regression analysis showed that there was a positive correlation between height and fat-free mass index [\u03b2, 1.99 (0.59, 3.39), <jats:italic>P<\/jats:italic>\u2009=\u20090.01], a negative correlation between height and body fat percentage [\u03b2, \u2212\u20090.20 (\u2212\u20090.38, \u2212\u20090.01), <jats:italic>P<\/jats:italic>\u2009=\u20090.04]. The proportions of fat-free mass in the upper limbs were significantly lower (Right,t\u2009=\u2009\u2212\u20092.78,Left t\u2009=\u2009\u2212\u20092.76, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05, respectively) in short stature, although body fat distribution was not.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The fat-free mass such as protein and bone minerals is lower in preschool children with short stature, suggesting the monitoring of fat-free mass for early identification and intervention.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12887-022-03159-8","type":"journal-article","created":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T05:02:46Z","timestamp":1645160566000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Body composition in preschool children with short stature: a case-control study"],"prefix":"10.1186","volume":"22","author":[{"given":"Yi-ting","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2435-0315","authenticated-orcid":false,"given":"Shi-zhong","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-yan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,2,18]]},"reference":[{"issue":"11","key":"3159_CR1","doi-asserted-by":"publisher","first-page":"4210","DOI":"10.1210\/jc.2008-0509","volume":"93","author":"P Cohen","year":"2008","unstructured":"Cohen P, Rogol AD, Deal CL, et al. 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