{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T04:01:54Z","timestamp":1794024114991,"version":"4.8.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Hirschsprung disease (HSCR) is a common congenital disorder presenting with functional obstruction due to aganglionosis of the colon. There are numerous types of pull-through surgery for managing HSCR, such as transabdominal endorectal (Soave), Swenson, Duhamel, transanal endorectal pull-through (TEPT), and laparoscopic (Georgeson) approach. Here, we aimed to describe the long-term outcome of patients with HSCR who underwent transabdominal Soave, Duhamel, and TEPT in our institution.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We performed a cross-sectional analysis for patients who underwent Duhamel, Soave, and TEPT at our institution from January 2012 to December 2015. Long-term functional outcome was determined by bowel function score (BFS). The BFS was obtained by interviewing patients who had completed at least three years of follow-up.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Twenty-five patients were included in this study who underwent transabdominal Soave (<jats:italic>n<\/jats:italic>\u2009=\u20098), Duhamel (<jats:italic>n<\/jats:italic>\u2009=\u20094), and TEPT (<jats:italic>n<\/jats:italic>\u2009=\u200913). There were 24 patients with short aganglionosis type. The median age of HSCR diagnosis was 10 (IQR\u2009=\u20091\u201339) months, while the median age of pull-through surgery was 17 (IQR\u2009=\u20097\u201347) months. The median follow-up of BFS level for HSCR patients after pull-through was 72 (IQR, 54\u201399) months. There were 11 patients with good BFS level and 10 patients with normal BFS level. Additionally, 50% of Duhamel patients had poor BFS level, while 50% of Soave patients had good BFS level, and 54% of TEPT patients had normal BFS level (<jats:italic>p<\/jats:italic>\u2009=\u20090.027). As many as 50% of Duhamel patients showed daily soiling and required protective aids, while 38.5% of TEPT had staining less than 1\/week and no change of underwear required, and 50% of Soave patients revealed no soiling, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.030). Furthermore, 75% of Duhamel patients had accidents, while 75% of Soave and 46.2% of TEPT patients had no accidents (<jats:italic>p<\/jats:italic>\u2009=\u20090.035).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Our study shows that the type of definitive surgery might affect the long-term bowel functional outcome; particularly, the TEPT approach might have some advantages over the transabdominal Soave and Duhamel procedures.\n<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12887-022-03301-6","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T08:02:56Z","timestamp":1651564976000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Long-term functional outcomes of patients with Hirschsprung disease following pull-through"],"prefix":"10.1186","volume":"22","author":[{"family":"Gunadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodora","family":"Monica Carissa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Stevie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezzah Fatmala","family":"Daulay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dicky","family":"Yulianda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristy","family":"Iskandar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andi","family":"Dwihantoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,3]]},"reference":[{"key":"3301_CR1","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/978-3-030-15647-3_10","volume-title":"Hirschsprung\u2019s Disease and Allied Disorders","author":"P Puri","year":"2019","unstructured":"Puri P, Nakamura H. Epidemiology and clinical characteristics of Hirschsprung\u2019s disease. In: Puri P, editor. Hirschsprung\u2019s Disease and Allied Disorders. Cham: Springer International Publishing; 2019. p. 167\u201372."},{"key":"3301_CR2","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1186\/s13104-018-3751-5","volume":"11","author":"Gunadi","year":"2018","unstructured":"Gunadi, Karina SM, Dwihantoro A. Outcomes in patients with Hirschsprung disease following definitive surgery. BMC Res Notes. 2018;11:644.","journal-title":"BMC Res Notes"},{"key":"3301_CR3","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-13-3606-5","volume-title":"Status Quo and Future Prospects of Treatment","author":"T Taguchi","year":"2019","unstructured":"Taguchi T, Matsufuji H, Ieiri S, et al. Hirschsprung\u2019s Disease and the Allied Disorders. In: Status Quo and Future Prospects of Treatment. 1st ed. 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Written informed consent was obtained from all parents for participating in this study. The research has been performed in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declared no potential conflicts of interest with respect to the research, authorship, and\/or publication of this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"246"}}