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There are conflicting\nstudies concerning whether sildenafil citrate (SC) reduces preterm labor\ncomplications. Therefore, the meta-analysis aimed to examine the clinical\noutcomes in women with threatened PTL who received nifedipine plus SC therapy\nversus only nifedipine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>For the original articles, six databases were searched using\nrelevant keywords without restriction on time or language until January 13,\n2024. The Cochrane risk-of-bias tool for randomized trials (RoB) and the Risk of\nBias Assessment Tool for Nonrandomized Studies (RoBANS) were both used to assess\nthe risk of bias in randomized and non-randomized studies, and GRADE determined\nthe quality of our evidence. Meta-analysis of all data was carried out using\nReview Manager (RevMan) version 5.1.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seven studies with mixed quality were included in the meta-analysis.\nThe study found that combining nifedipine and SC resulted in more prolongation\nof pregnancy (MD\u2009=\u20096.99, 95% CI: 5.32, 8.65,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001), a lower rate of delivery in the 1st to 3rd days\nafter hospitalization (RR\u2009=\u20090.62, 95% CI: 0.50, 0.76,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001), a higher birth weight (252.48\u00a0g vs. nifedipine\nalone,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), and the risk ratio of\nadmission to the neonatal intensive care unit (NICU) was significantly lower\n(RR\u2009=\u20090.62, 95% CI: 0.50, 0.76,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001) compared to nifidepine alone. The evidence was high\nfor prolongation of pregnancy, delivery rate 24\u201372\u00a0h after admission, and NICU\nadmission, but low for newborn birth weight.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Given the effectiveness of SC plus nifedipine in increased\nprolongation of pregnancy and birth weight, lower delivery in the 1st to 3rd\ndays after hospitalization, and NICU admission, Gynecologists and obstetricians\nare suggested to consider this strategy for PTL management, although additional\narticle rigor is required to improve the quality of the evidence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12887-024-04588-3","type":"journal-article","created":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T05:02:48Z","timestamp":1707541368000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["RETRACTED ARTICLE: Efficient administration of a combination of nifedipine and sildenafil citrate versus only nifedipine on clinical outcomes in women with threatened preterm labor: a systematic review and meta-analysis"],"prefix":"10.1186","volume":"24","author":[{"given":"Elham","family":"Manouchehri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6351-1372","authenticated-orcid":false,"given":"Somayeh","family":"Makvandi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2891-4333","authenticated-orcid":false,"given":"Mahdieh","family":"Razi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Sahebari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Larki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,10]]},"reference":[{"issue":"10409","key":"4588_CR1","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1016\/S0140-6736(23)00878-4","volume":"402","author":"EO Ohuma","year":"2023","unstructured":"Ohuma EO, Moller A-B, Bradley E, Chakwera S, Hussain-Alkhateeb L,\nLewin A, et al. 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Appropriate editorial action will be taken once this matter is resolved.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 February 2026","order":8,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":9,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article has been retracted. 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