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Although it is safe for physicians and nurses to place, complications like infection, occlusion, phlebitis, and bleeding can occur. We report a 5-month-old infant who suffered respiratory failure caused by catheter malposition resulting in massive fluid infusion into the thoracic cavity. Point-of-care ultrasound (POCUS) was utilized to identify a massive pleural effusion that prompted urgent drainage. Complications related to PICC in pediatric patients are not common but difficult to immediately identify sometimes. Therefore, careful attention should be paid by physicians to identify and reduce the risk of complications associated with PICC. Thus, visual tools are strongly advised to enhance the safety of invasive procedures.<\/jats:p>","DOI":"10.1186\/s12887-024-04856-2","type":"journal-article","created":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T04:02:27Z","timestamp":1720584147000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["PICC tip dislodgement causing massive pleural effusion and atelectasis with acute respiratory failure: a case report"],"prefix":"10.1186","volume":"24","author":[{"given":"Yao","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Felipe","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanhong","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"issue":"3","key":"4856_CR1","doi-asserted-by":"publisher","first-page":"298","DOI":"10.25122\/jml-2020-0011","volume":"14","author":"G Bahoush","year":"2021","unstructured":"Bahoush G, Department of Pediatrics, Ali Asghar Children Hospital, Tehran, Iran (the Islamic Republic of), Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran (the Islamic Republic of). 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