{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T15:18:12Z","timestamp":1785338292634,"version":"3.55.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:00:00Z","timestamp":1724457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:00:00Z","timestamp":1724457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"DOI":"10.1186\/s12887-024-05006-4","type":"journal-article","created":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T04:02:43Z","timestamp":1724472163000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Two cases of Leukemoid reaction in premature infants caused by fetal inflammatory response syndrome"],"prefix":"10.1186","volume":"24","author":[{"given":"Meng-Ting","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan-Dan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,24]]},"reference":[{"issue":"1","key":"5006_CR1","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/S0002-9378(98)70272-8","volume":"179","author":"R Gomez","year":"1998","unstructured":"Gomez R, Romero R, Ghezzi F, Yoon BH, Mazor M, Berry SM. The fetal inflammatory response syndrome. Am J Obstet Gynecol. 1998;179(1):194\u2013202.","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"5006_CR2","doi-asserted-by":"publisher","first-page":"101146","DOI":"10.1016\/j.siny.2020.101146","volume":"25","author":"E Jung","year":"2020","unstructured":"Jung E, Romero R, Yeo L, Diaz-Primera R, Marin-Concha J, Para R, et al. The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications. Seminars Fetal Neonatal Med. 2020;25(4):101146.","journal-title":"Seminars Fetal Neonatal Med"},{"issue":"1","key":"5006_CR3","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1080\/jmf.11.1.18.25","volume":"11","author":"P Pacora","year":"2002","unstructured":"Pacora P, Chaiworapongsa T, Maymon E, Kim YM, Gomez R, Yoon BH, et al. Funisitis and chorionic vasculitis: the histological counterpart of the fetal inflammatory response syndrome. J Maternal-Fetal Neonatal Med. 2002;11(1):18\u201325.","journal-title":"J Maternal-Fetal Neonatal Med"},{"issue":"1","key":"5006_CR4","first-page":"19","volume":"40","author":"R Romero","year":"2011","unstructured":"Romero R, Savasan ZA, Chaiworapongsa T, Berry SM, Kusanovic JP, Hassan SS, et al. Hematologic profile of the fetus with systemic inflammatory response syndrome. J Perinat Med. 2011;40(1):19\u201332.","journal-title":"J Perinat Med"},{"issue":"1","key":"5006_CR5","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.humpath.2005.09.017","volume":"37","author":"V Zanardo","year":"2006","unstructured":"Zanardo V, Vedovato S, Trevisanuto DD, Suppiej A, Cosmi E, Fais GF, et al. Histological chorioamnionitis and neonatal leukemoid reaction in low-birth-weight infants. Hum Pathol. 2006;37(1):87\u201391.","journal-title":"Hum Pathol"},{"issue":"10","key":"5006_CR6","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1038\/jp.2008.78","volume":"28","author":"I Morag","year":"2008","unstructured":"Morag I, Dunn M, Nayot D, Shah PS. Leukocytosis in very low birth weight neonates: associated clinical factors and neonatal outcomes. J Perinatol. 2008;28(10):680\u20134.","journal-title":"J Perinatol"},{"issue":"11","key":"5006_CR7","doi-asserted-by":"publisher","first-page":"e998","DOI":"10.1016\/j.ijid.2010.06.012","volume":"14","author":"R Duran","year":"2010","unstructured":"Duran R, \u00d6zbek \u00dcV, \u00c7iftdemir NA, Acuna\u015f B, S\u00fct N. The relationship between leukemoid reaction and perinatal morbidity, mortality, and chorioamnionitis in low birth weight infants. Int J Infect Dis. 2010;14(11):e998\u20131001.","journal-title":"Int J Infect Dis"},{"issue":"5","key":"5006_CR8","doi-asserted-by":"publisher","first-page":"588","DOI":"10.3109\/14767058.2014.927426","volume":"28","author":"EN Kim","year":"2015","unstructured":"Kim EN, Kim CJ, Park JW, Yoon BH. Acute funisitis is associated with distinct changes in fetal hematologic profile. J Matern Fetal Neonatal Med. 2015;28(5):588\u201393.","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"6","key":"5006_CR9","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1515\/jpm.2011.072","volume":"39","author":"T Chaiworapongsa","year":"2011","unstructured":"Chaiworapongsa T, Romero R, Berry SM, Hassan SS, Yoon BH, Edwin S, et al. The role of Granulocyte colony-stimulating factor in the Neutrophilia Observed in the fetal inflammatory response syndrome. J Perinat Med. 2011;39(6):653\u201366.","journal-title":"J Perinat Med"},{"issue":"2","key":"5006_CR10","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1620\/tjem.244.145","volume":"244","author":"T Nakamura","year":"2018","unstructured":"Nakamura T, Hatanaka D, Kusakari M, Kashima K, Takizawa Y, Takahashi H, et al. Neonatal leukemoid reaction with fetal inflammatory response syndrome is Associated with elevated serum granulocyte colony stimulating factor and Interleukin-6. Tohoku J Exp Med. 2018;244(2):145\u20139.","journal-title":"Tohoku J Exp Med"},{"issue":"5","key":"5006_CR11","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1515\/JPM.2009.106","volume":"37","author":"SK Kim","year":"2009","unstructured":"Kim SK, Romero R, Chaiworapongsa T, Kusanovic JP, Mazaki-Tovi S, Mittal P, et al. Evidence of changes in the immunophenotype and metabolic characteristics (intracellular reactive oxygen radicals) of fetal, but not maternal, monocytes and granulocytes in the fetal inflammatory response syndrome. J Perinat Med. 2009;37(5):543\u201352.","journal-title":"J Perinat Med"}],"container-title":["BMC Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12887-024-05006-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12887-024-05006-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12887-024-05006-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T04:04:01Z","timestamp":1724472241000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpediatr.biomedcentral.com\/articles\/10.1186\/s12887-024-05006-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,24]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["5006"],"URL":"https:\/\/doi.org\/10.1186\/s12887-024-05006-4","relation":{},"ISSN":["1471-2431"],"issn-type":[{"value":"1471-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,24]]},"assertion":[{"value":"27 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was obtained from the ethical committee of The First Hospital of Jilin University. The committee\u2019s reference number was: 2024-070. Informed Consent from patients\u2019\u00a0parents was obtained","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The patient\u2019s guardian provided written informed consent for the publication of the data. Informed consent for the publication of identifiable information\/ images in open-access journals was obtained from parents.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"546"}}