{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:22:17Z","timestamp":1757618537832,"version":"3.44.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"DOI":"10.1186\/s12887-025-05908-x","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T08:53:40Z","timestamp":1752137620000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["COVID-19-associated multiple colonic perforations in a 6-month-old infant: a rare case report"],"prefix":"10.1186","volume":"25","author":[{"given":"Ali Manafi","family":"Anari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ladan","family":"Teymoorzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramez","family":"Nasiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajjad","family":"Narimani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"issue":"3","key":"5908_CR1","doi-asserted-by":"publisher","first-page":"244","DOI":"10.3390\/diagnostics14030244","volume":"14","author":"N Negrut","year":"2024","unstructured":"Negrut N, et al. The multisystem impact of long COVID: a comprehensive review. Diagnostics. 2024;14(3):244.","journal-title":"Diagnostics"},{"issue":"2","key":"5908_CR2","doi-asserted-by":"publisher","first-page":"e2458366","DOI":"10.1001\/jamanetworkopen.2024.58366","volume":"8","author":"D Zhang","year":"2025","unstructured":"Zhang D, et al. Pediatric gastrointestinal tract outcomes during the postacute phase of COVID-19. JAMA Network Open. 2025;8(2):e2458366.","journal-title":"JAMA Network Open"},{"issue":"2","key":"5908_CR3","doi-asserted-by":"publisher","first-page":"G93","DOI":"10.1152\/ajpgi.00229.2022","volume":"325","author":"L Valdetaro","year":"2023","unstructured":"Valdetaro L, et al. Enteric nervous system as a target and source of SARS-CoV-2 and other viral infections. Am J Physiol-Gastrointestinal Liver Physiol. 2023;325(2):G93\u2013108.","journal-title":"Am J Physiol-Gastrointestinal Liver Physiol."},{"key":"5908_CR4","doi-asserted-by":"publisher","unstructured":"Lone Y A, Singh S K, Naaz A, et al. Tiny Tummies, Big Challenges: A Case Series of Neonatal Gastric Perforations. Cureus. 2024;16(4):e58149. https:\/\/doi.org\/10.7759\/cureus.58149.","DOI":"10.7759\/cureus.58149"},{"issue":"19","key":"5908_CR5","doi-asserted-by":"publisher","first-page":"e25771","DOI":"10.1097\/MD.0000000000025771","volume":"100","author":"RJ Al Argan","year":"2021","unstructured":"Al Argan RJ, et al. Gastrointestinal perforation secondary to COVID-19: case reports and literature review. Medicine. 2021;100(19):e25771.","journal-title":"Medicine"},{"issue":"1","key":"5908_CR6","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1177\/1074248420958973","volume":"26","author":"AS Manolis","year":"2021","unstructured":"Manolis AS, et al. COVID-19 infection: viral macro-and micro-vascular coagulopathy and thromboembolism\/prophylactic and therapeutic management. J Cardiovasc Pharmacol Therapeutics. 2021;26(1):12\u201324.","journal-title":"J Cardiovasc Pharmacol Therapeutics"},{"issue":"2","key":"5908_CR7","doi-asserted-by":"publisher","first-page":"68","DOI":"10.5501\/wjv.v12.i2.68","volume":"12","author":"EP Tsounis","year":"2023","unstructured":"Tsounis EP, et al. Intestinal barrier dysfunction as a key driver of severe COVID-19. World J Virol. 2023;12(2):68.","journal-title":"World J Virol"},{"key":"5908_CR8","doi-asserted-by":"crossref","unstructured":"Guney C, Akar F. Epithelial and endothelial expressions of ACE2: SARS-CoV-2 entry routes. J Pharm Pharm Sci.\u00a02021;24:84\u201393.\u00a0https:\/\/www.cspsCanada.org.","DOI":"10.18433\/jpps31455"},{"key":"5908_CR9","doi-asserted-by":"publisher","first-page":"594495","DOI":"10.3389\/fmed.2020.594495","volume":"7","author":"F Salamanna","year":"2020","unstructured":"Salamanna F, et al. Body localization of ACE-2: on the trail of the keyhole of SARS-CoV-2. Front Med. 2020;7:594495.","journal-title":"Front Med"},{"issue":"2","key":"5908_CR10","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/S0049-3848(02)00006-3","volume":"105","author":"S Kiraz","year":"2002","unstructured":"Kiraz S, et al. Pathological haemostasis and \u2018prothrombotic state\u2019in Beh\u00e7et\u2019s disease. Thromb Research. 2002;105(2):125\u201333.","journal-title":"Thromb Research"},{"issue":"11","key":"5908_CR11","doi-asserted-by":"publisher","first-page":"7483","DOI":"10.4103\/jfmpc.jfmpc_1284_22","volume":"11","author":"S Roy","year":"2022","unstructured":"Roy S, Jha VN, Ranjan B. A case series of coagulopathy in preterm or growth-restricted term neonates born to mothers with antenatal SARS-CoV-2 infection: Neonatal post-COVID-19 coagulopathy? J Fam Med Prim Care. 2022;11(11):7483\u201390.","journal-title":"J Fam Med Prim Care"},{"issue":"19","key":"5908_CR12","doi-asserted-by":"publisher","first-page":"11740","DOI":"10.3390\/ijms231911740","volume":"23","author":"D Jarczak","year":"2022","unstructured":"Jarczak D, Nierhaus A. Cytokine storm\u2014definition, causes, and implications. Int J Mol Sci. 2022;23(19):11740.","journal-title":"Int J Mol Sci"},{"issue":"3","key":"5908_CR13","doi-asserted-by":"publisher","first-page":"226","DOI":"10.3390\/immuno4030015","volume":"4","author":"A Zari","year":"2024","unstructured":"Zari A, et al. Interplay between multisystem inflammatory syndrome in children, interleukin 6, microbiome, and gut barrier integrity. Immuno. 2024;4(3):226\u201346.","journal-title":"Immuno"},{"issue":"11","key":"5908_CR14","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.3390\/children9111745","volume":"9","author":"S Alhumaid","year":"2022","unstructured":"Alhumaid S, et al. Intussusception and COVID-19 in children: a systematic review and meta-analysis. Children. 2022;9(11):1745.","journal-title":"Children"},{"key":"5908_CR15","doi-asserted-by":"publisher","first-page":"659069","DOI":"10.3389\/fped.2021.659069","volume":"9","author":"SSP Oi","year":"2021","unstructured":"Oi SSP, et al. Multisystemic inflammatory syndrome and thrombotic microangiopathy as complications of COVID-19 in a child: a case report. Front Pediatr. 2021;9:659069.","journal-title":"Front Pediatr"},{"key":"5908_CR16","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1007\/s10620-020-06408-x","volume":"65","author":"P Patel","year":"2020","unstructured":"Patel P, Sengupta N. PPIs and beyond: a framework for managing anticoagulation-related gastrointestinal bleeding in the era of COVID-19. Dig Dis Sci. 2020;65:2181\u20136.","journal-title":"Dig Dis Sci"},{"issue":"23","key":"5908_CR17","first-page":"2033","volume":"135","author":"JM Connors","year":"2020","unstructured":"Connors JM, Levy JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood, J Am Soc Hematol. 2020;135(23):2033\u201340.","journal-title":"Blood, J Am Soc Hematol"}],"container-title":["BMC Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12887-025-05908-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12887-025-05908-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12887-025-05908-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T03:31:26Z","timestamp":1757215886000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpediatr.biomedcentral.com\/articles\/10.1186\/s12887-025-05908-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,10]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5908"],"URL":"https:\/\/doi.org\/10.1186\/s12887-025-05908-x","relation":{},"ISSN":["1471-2431"],"issn-type":[{"type":"electronic","value":"1471-2431"}],"subject":[],"published":{"date-parts":[[2025,7,10]]},"assertion":[{"value":"21 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was obtained from the Department of Pediatrics, Ali Asghar Children Hospital, Iran University of Medical Sciences.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Informed consent for publication of clinical details was obtained from the parents of the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"545"}}