{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T15:18:16Z","timestamp":1723216696931},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T00:00:00Z","timestamp":1633478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T00:00:00Z","timestamp":1633478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Psychiatry"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Functional networks develop throughout adolescence when anorexia nervosa (AN) normally debuts. In AN, cerebral structural alterations are found in most brain regions and may be related to the observed functional brain changes. Few studies have investigated the functional networks of the brain in adolescent AN patients.. The aim of this explorative study was to investigate multiple functional networks in adolescent AN patients compared to healthy age-matched controls (HC) and the relationship with age, eating disorder symptoms and structural alterations.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Included were 29 female inpatients with restrictive AN, and 27 HC. All participants were between the ages of 12 to 18\u2009years. Independent component analysis (ICA) identified 21 functional networks that were analyzed with multivariate and univariate analyses of components and group affiliation (AN vs HC). Age, age \u00d7 group interaction and AN symptoms were included as covariates. Follow-up correlational analyses of selected components and structural measures (cortical thickness and subcortical volume) were carried out.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Decreased functional connectivity (FC) in AN patients was found in one cortical network, involving mainly the precuneus, and identified as a default mode network (DMN). Cortical thickness in the precuneus was significantly correlated with functional connectivity in this network. Significant group differences were also found in two subcortical networks involving mainly the hippocampus and the amygdala respectively, and a significant interaction effect of age and group was found in both these networks. There were no significant associations between FC and the clinical measures used in the study.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The findings from the present study may imply that functional alterations are related to structural alterations in selected regions and that the restricted food intake in AN patients disrupt normal age-related development of functional networks involving the amygdala and hippocampus.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12888-021-03497-4","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T01:48:04Z","timestamp":1633571284000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Altered functional connectivity in adolescent anorexia nervosa is related to age and cortical thickness"],"prefix":"10.1186","volume":"21","author":[{"given":"Anna D.","family":"Myrvang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torgil R.","family":"Vangberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clas","family":"Linnman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin","family":"Stedal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d8yvind","family":"R\u00f8","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tor","family":"Endestad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan H.","family":"Rosenvinge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per M.","family":"Aslaksen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,10,6]]},"reference":[{"issue":"7","key":"3497_CR1","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1016\/j.biopsych.2014.09.005","volume":"77","author":"JA King","year":"2015","unstructured":"King JA, Geisler D, Ritschel F, Boehm I, Seidel M, Roschinski B, et al. Global cortical thinning in acute anorexia nervosa normalizes following long-term weight restoration. Biol Psychiatry. 2015;77(7):624\u201332 [cited 2016 Oct 7]. Available from: http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006322314007045.","journal-title":"Biol Psychiatry"},{"issue":"8","key":"3497_CR2","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1007\/s00702-016-1567-9","volume":"123","author":"J Seitz","year":"2016","unstructured":"Seitz J, Herpertz-Dahlmann B, Konrad K. Brain morphological changes in adolescent and adult patients with anorexia nervosa. J Neural Transm. 2016;123(8):949\u201359 Springer Vienna; Available from: https:\/\/link.springer.com\/article\/10.1007\/s00702-016-1567-9.","journal-title":"J Neural Transm"},{"key":"3497_CR3","doi-asserted-by":"crossref","unstructured":"Myrvang AD, Vangberg TR, Stedal K, R\u00f8 \u00d8, Endestad T, Rosenvinge JH, et al. Cerebral cortical thickness and surface area in adolescent anorexia nervosa: Separate and joint analyses with a permutation-based nonparametric method. Int J Eat Disord. 2020; John Wiley & Sons, Ltd; [cited 2021 Jan 5];Advance on. Available from: https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/eat.23448.","DOI":"10.1002\/eat.23448"},{"issue":"8","key":"3497_CR4","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1016\/j.neubiorev.2012.05.003","volume":"36","author":"S Gaudio","year":"2012","unstructured":"Gaudio S, Quattrocchi CC. Neural basis of a multidimensional model of body image distortion in anorexia nervosa. Neurosci Biobehav Rev. 2012;36(8):1839\u201347 [cited 2016 Feb 23] Available from: http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0149763412000759.","journal-title":"Neurosci Biobehav Rev"},{"key":"3497_CR5","doi-asserted-by":"crossref","unstructured":"Chao AM, Roy A, Franks AT, Joseph PV. A Systematic Review of Taste Differences Among People With Eating Disorders. Biol Res Nurs. 22(1):82\u201391 SAGE Publications Inc.; 2020 Jan 1 [cited 2021 Jun 17]. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/31833410\/.","DOI":"10.1177\/1099800419872824"},{"key":"3497_CR6","volume-title":"BOLD fMRI a guide to functional imaging for neuroscientists","author":"SH Faro","year":"2010","unstructured":"Faro SH, Mohamed FB. BOLD fMRI a guide to functional imaging for neuroscientists. London: Springer; 2010. Available from: http:\/\/link.springer.com\/10.1007\/978-1-4419-1329-6"},{"issue":"37","key":"3497_CR7","doi-asserted-by":"publisher","first-page":"13848","DOI":"10.1073\/pnas.0601417103","volume":"103","author":"JS Damoiseaux","year":"2006","unstructured":"Damoiseaux JS, Rombouts SARB, Barkhof F, Scheltens P, Stam CJ, Smith SM, et al. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci U S A. 2006;103(37):13848\u201353. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/16945915\/. https:\/\/doi.org\/10.1073\/pnas.0601417103.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"3497_CR8","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1146\/annurev-neuro-071013-014030","volume":"38","author":"ME Raichle","year":"2015","unstructured":"Raichle ME. The Brain\u2019s Default Mode Network. Annu Rev Neurosci. 2015;38(1):433\u201347 Annual Reviews Inc.;. Available from: https:\/\/www.annualreviews.org\/doi\/pdf\/10.1146\/annurev-neuro-071013-014030.","journal-title":"Annu Rev Neurosci"},{"issue":"1","key":"3497_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1196\/annals.1440.011","volume":"1124","author":"RL Buckner","year":"2008","unstructured":"Buckner RL, Andrews-Hanna JR, Schacter DL. The brain\u2019s default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci [Internet]. 2008;1124(1):1\u201338. Available from: https:\/\/psycnet.apa.org\/record\/2008-05643-001. https:\/\/doi.org\/10.1196\/annals.1440.011.","journal-title":"Ann N Y Acad Sci [Internet]"},{"issue":"10","key":"3497_CR10","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1016\/j.biopsych.2012.04.025","volume":"72","author":"A Favaro","year":"2012","unstructured":"Favaro A, Santonastaso P, Manara R, Bosello R, Bommarito G, Tenconi E, et al. Disruption of visuospatial and somatosensory functional connectivity in anorexia nervosa. Biol Psychiatry. 2012;72(10):864\u201370 [cited 2015 Jul 30]. Available from: http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006322312004088.","journal-title":"Biol Psychiatry"},{"key":"3497_CR11","doi-asserted-by":"publisher","first-page":"346","DOI":"10.3389\/fnbeh.2014.00346","volume":"8","author":"I Boehm","year":"2014","unstructured":"Boehm I, Geisler D, King JA, Ritschel F, Seidel M, Deza Araujo Y, et al. Increased resting state functional connectivity in the fronto-parietal and default mode network in anorexia nervosa. Front Behav Neurosci. 2014;8:346 [cited 2015 Dec 1]. Available from: http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=4183185&tool=pmcentrez&rendertype=abstract.","journal-title":"Front Behav Neurosci"},{"key":"3497_CR12","first-page":"554","volume":"271","author":"MT Plana","year":"2019","unstructured":"Plana MT, Torres T, Rodr\u00edguez N, Boloc D, Gass\u00f3 P, Moreno E, et al. Genetic variability in the serotoninergic system and age of onset in anorexia nervosa and obsessive-compulsive disorder. Psychiatry res [internet]. Elsevier Ireland Ltd. 2019;271:554\u20138 Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0165178118314021?casa_token=rw6WqxCYur8AAAAA:1H5hLB3lLgbG51P4RiOXagzrSPMRQwYNrtkHcUgoZ9oFAMdO5T5ao7199OW-jF8A6301_RN4bmH4.","journal-title":"Elsevier Ireland Ltd"},{"issue":"8","key":"3497_CR13","doi-asserted-by":"publisher","first-page":"2356","DOI":"10.1002\/hbm.20673","volume":"30","author":"MC Stevens","year":"2009","unstructured":"Stevens MC, Pearlson GD, Calhoun VD. Changes in the interaction of resting-state neural networks from adolescence to adulthood. Hum Brain Mapp. 2009;30(8):2356\u201366 Available from: https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/hbm.20673.","journal-title":"Hum Brain Mapp"},{"issue":"4","key":"3497_CR14","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1503\/jpn.140193","volume":"40","author":"K-J B\u00e4r","year":"2015","unstructured":"B\u00e4r K-J, de la Cruz F, Berger S, Schultz CC, Wagner G. Structural and functional differences in the cingulate cortex relate to disease severity in anorexia nervosa. J Psychiatry Neurosci. 2015;40(4):269\u201379. Available from: http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=4478060&tool=pmcentrez&rendertype=abstract. https:\/\/doi.org\/10.1503\/jpn.140193.","journal-title":"J Psychiatry Neurosci"},{"key":"3497_CR15","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3389\/fpsyt.2017.00030","volume":"8","author":"JC Scaife","year":"2017","unstructured":"Scaife JC, Godier LR, Filippini N, Harmer CJ, Park RJ. Reduced Resting-State Functional Connectivity in Current and Recovered Restrictive Anorexia Nervosa. Front Psychiatry. 2017;8:30 Frontiers Media SA; [cited 2017 Nov 2]. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28400737.","journal-title":"Front Psychiatry"},{"key":"3497_CR16","doi-asserted-by":"publisher","unstructured":"de la Cruz F, Schumann A, Suttkus S, Helbing N, Zopf R, B\u00e4r KJ. Cortical thinning and associated connectivity changes in patients with anorexia nervosa. Transl Psychiatry [Internet]. Springer Nature. 2021;11(1):95. Available from: https:\/\/doi.org\/10.1038\/s41398-021-01237-6.\u00a0[cited 2021 Jun 11].","DOI":"10.1038\/s41398-021-01237-6"},{"issue":"11","key":"3497_CR17","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1016\/j.jaac.2019.01.011","volume":"58","author":"M Seidel","year":"2019","unstructured":"Seidel M, Borchardt V, Geisler D, King JA, Boehm I, Pauligk S, et al. Abnormal spontaneous regional brain activity in young patients with anorexia nervosa. J Am Acad Child Adolesc Psychiatry. 2019;58(11):1104\u201314. https:\/\/doi.org\/10.1016\/j.jaac.2019.01.011.","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"1","key":"3497_CR18","doi-asserted-by":"publisher","first-page":"10818","DOI":"10.1038\/srep10818","volume":"5","author":"S Gaudio","year":"2015","unstructured":"Gaudio S, Piervincenzi C, Zobel BB, Montecchi FR, Riva G, Carducci F, et al. Altered resting state functional connectivity of anterior cingulate cortex in drug na\u00efve adolescents at the earliest stages of anorexia nervosa. Sci Rep. 2015;5(1):10818. https:\/\/doi.org\/10.1038\/srep10818.","journal-title":"Sci Rep"},{"issue":"3","key":"3497_CR19","doi-asserted-by":"publisher","first-page":"220","DOI":"10.3109\/03014460.2012.759276","volume":"40","author":"PB J\u00fal\u00edusson","year":"2013","unstructured":"J\u00fal\u00edusson PB, Roelants M, Nordal E, Furevik L, Eide GE, Moster D, et al. Growth references for 0\u201319 year-old Norwegian children for length\/height, weight, body mass index and head circumference. Ann Hum Biol. 2013;40(3):220\u20137 Available from: http:\/\/www.tandfonline.com\/doi\/full\/10.3109\/03014460.2012.759276.","journal-title":"Ann Hum Biol"},{"key":"3497_CR20","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.pscychresns.2018.10.007","volume":"282","author":"AD Myrvang","year":"2018","unstructured":"Myrvang AD, Vangberg TR, Stedal K, R\u00f8 \u00d8, Endestad T, Rosenvinge JH, et al. Hippocampal subfields in adolescent anorexia nervosa. Psychiatry Res Neuroimaging. 2018;282:24\u201330 Elsevier; [cited 2018 Nov 5]. Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0925492718301550?dgcid=author.","journal-title":"Psychiatry Res Neuroimaging"},{"key":"3497_CR21","unstructured":"ICA-AROMA [Internet]. [cited 2018 Nov 8]. Available from: https:\/\/github.com\/maartenmennes\/ICA-AROMA"},{"key":"3497_CR22","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.neuroimage.2015.02.064","volume":"112","author":"RHR Pruim","year":"2015","unstructured":"Pruim RHR, Mennes M, van Rooij D, Llera A, Buitelaar JK, Beckmann CF, et al. A robust ICA-based strategy for removing motion artifacts from fMRI data. Neuroimage. 2015;112:267\u201377 Academic Press; [cited 2018 Nov 8]. Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1053811915001822.","journal-title":"Neuroimage"},{"key":"3497_CR23","unstructured":"Group ICA toolbox (GIFT and EEGIFT) [Internet]. [cited 2018 Dec 1]. Available from: http:\/\/icatb.sourceforge.net\/"},{"issue":"1457","key":"3497_CR24","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1098\/rstb.2005.1634","volume":"360","author":"CF Beckmann","year":"2005","unstructured":"Beckmann CF, DeLuca M, Devlin JT, Smith SM. Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc Lond B Biol Sci. 2005;360(1457):1001\u201313 [cited 2014 Jul 10]. Available from: http:\/\/rstb.royalsocietypublishing.org\/content\/360\/1457\/1001.short.","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"31","key":"3497_CR25","doi-asserted-by":"publisher","first-page":"13040","DOI":"10.1073\/pnas.0905267106","volume":"106","author":"SM Smith","year":"2009","unstructured":"Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, et al. Correspondence of the brain\u2019s functional architecture during activation and rest. Proc Natl Acad Sci U S A. 2009;106(31):13040\u20135 [cited 2014 Jul 10]. Available from: http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=2722273&tool=pmcentrez&rendertype=abstract.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3497_CR26","first-page":"2","volume":"5","author":"EA Allen","year":"2011","unstructured":"Allen EA, Erhardt EB, Damaraju E, Gruner W, Segall JM, Silva RF, et al. A baseline for the multivariate comparison of resting-state networks. Front Syst Neurosci. 2011;5:2 [cited 2015 Jun 25]. Available from: http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=3051178&tool=pmcentrez&rendertype=abstract.","journal-title":"Front Syst Neurosci"},{"issue":"5","key":"3497_CR27","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1016\/j.mri.2006.10.017","volume":"25","author":"N Correa","year":"2007","unstructured":"Correa N, Adali T, Calhoun VD. Performance of blind source separation algorithms for FMRI analysis using a group ICA method. Neuropsychiatry (London). 2007;25(5):684\u201394. Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0730725X06003080?casa_token=wUzIhwAt-54AAAAA:znX587M4ng2mrng_YeHerRd9_TsCr_ZN_bYHCf7Dmz0cLIPZJxEkteRPYbG6LaGXnX1NtmVaMypB. https:\/\/doi.org\/10.1016\/j.mri.2006.10.017.","journal-title":"Neuropsychiatry (London)"},{"key":"3497_CR28","first-page":"309","volume-title":"Cognitive Behavior Therapy and Eating Disorders","author":"CG Fairburn","year":"2008","unstructured":"Fairburn CG, Beglin S. Eating disorder examination questionnaire (EDE-Q 6.0). In: Fairburn CG, editor. Cognitive Behavior Therapy and Eating Disorders. New York: Guilford Press; 2008. p. 309\u201313."},{"key":"3497_CR29","unstructured":"FreeSurfer [Internet]. Available from: https:\/\/surfer.nmr.mgh.harvard.edu\/"},{"issue":"3","key":"3497_CR30","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S0896-6273(02)00569-X","volume":"33","author":"B Fischl","year":"2002","unstructured":"Fischl B, Salat DH, Busa E, Albert M, Dieterich M, Haselgrove C, et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron. 2002;33(3):341\u201355. Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S089662730200569X. https:\/\/doi.org\/10.1016\/S0896-6273(02)00569-X.","journal-title":"Neuron"},{"issue":"1","key":"3497_CR31","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1093\/cercor\/bhg087","volume":"14","author":"B Fischl","year":"2004","unstructured":"Fischl B, Van Der Kouwe A, Destrieux C, Halgren E, S\u00e9gonne F, Salat DH, et al. Automatically parcellating the human cerebral cortex. Cereb Cortex. 2004;14(1):11\u201322. https:\/\/doi.org\/10.1093\/cercor\/bhg087.","journal-title":"Cereb Cortex"},{"issue":"3","key":"3497_CR32","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","volume":"31","author":"RS Desikan","year":"2006","unstructured":"Desikan RS, S\u00e9gonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006;31(3):968\u201380 Academic Press; [cited 2020 Jun 12]Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1053811906000437?casa_token=7RPxkhyy-gQAAAAA:NYT7BJhztIhNqRL1sE9koRkgs5_g9dvUxvGUmb4yEdeiSO1VzgLP-W4w3K6d4rRgW_kT6scQw7-J.","journal-title":"Neuroimage"},{"issue":"3","key":"3497_CR33","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1523\/JNEUROSCI.4227-13.2014","volume":"34","author":"AV Utevsky","year":"2014","unstructured":"Utevsky AV, Smith DV, Huettel SA. Precuneus is a functional core of the default-mode network. J Neurosci. 2014;34(3):932\u201340 [cited 2021 Mar 30];Society for Neuroscience;. Available from: http:\/\/www.fmrib.ox.ac.uk\/fsl\/.","journal-title":"J Neurosci"},{"key":"3497_CR34","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1017\/S0033291709991826","volume":"40","author":"HM Mohr","year":"2009","unstructured":"Mohr HM, Zimmermann J, R\u00f6 Der C, Lenz C, Overbeck G, Grabhorn R. Separating two components of body image in anorexia nervosa using fMRI. Psychol Med. 2009;40:1519\u201329 Available from: https:\/\/scholar.google.com\/scholar_url?url=https:\/\/search.proquest.com\/openview\/aa782871e3ba2e4592318ea0ec930e00\/1%3Fpq-origsite%3Dgscholar%26cbl%3D35753%26casa_token%3DicgxeQvWynEAAAAA:PD4ocde0IZucKSxJaPT1DCBgsU5yAHCzHRS3vPfwgEhYB_bGPO0VofdVhwjg6uR5Fyye6CwyYqzP&hl=no&sa=T&oi=gsb-ggp&ct=res&cd=0&d=18188110132047744272&ei=HVbMYNSOGIXSmAGuvJ7YDw&scisig=AAGBfm0ulKlUhcSvIg5nd_SWNrPKh2ot5Q.","journal-title":"Psychol Med"},{"issue":"3","key":"3497_CR35","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1503\/jpn.130046","volume":"39","author":"KL McFadden","year":"2014","unstructured":"McFadden KL, Tregellas JR, Shott ME, GKW F. Reduced salience and default mode network activity in women with anorexia nervosa. J Psychiatry Neurosci. 2014;39(3):178\u201388 [cited 2015 Jul 30]. Available from: http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=3997603&tool=pmcentrez&rendertype=abstract.","journal-title":"J Psychiatry Neurosci"},{"issue":"1","key":"3497_CR36","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.pscychresns.2013.11.004","volume":"221","author":"S Lee","year":"2014","unstructured":"Lee S, Ran Kim K, Ku J, Lee JH, Namkoong K, Jung YC. Resting-state synchrony between anterior cingulate cortex and precuneus relates to body shape concern in anorexia nervosa and bulimia nervosa. Psychiatry Res - Neuroimaging. 2014;221(1):43\u20138 Elsevier; [cited 2021 Jun 17]. Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0925492713003120.","journal-title":"Psychiatry Res - Neuroimaging"},{"issue":"9","key":"3497_CR37","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1002\/eat.22918","volume":"51","author":"K Nickel","year":"2018","unstructured":"Nickel K, Joos A, Tebartz van Elst L, Matthis J, Holovics L, Endres D, et al. Recovery of cortical volume and thickness after remission from acute anorexia nervosa. Int J Eat Disord. 2018;51(9):1056\u201369 [cited 2019 Aug 8]. John Wiley & Sons, Ltd; Available from: http:\/\/doi.wiley.com\/10.1002\/eat.22918.","journal-title":"Int J Eat Disord"},{"key":"3497_CR38","doi-asserted-by":"publisher","first-page":"2686","DOI":"10.1002\/erv.2686","volume":"erv","author":"J Leppanen","year":"2019","unstructured":"Leppanen J, Sedgewick F, Cardi V, Treasure J, Tchanturia K. Cortical morphometry in anorexia nervosa: An out-of-sample replication study. Eur Eat Disord Rev. 2019;erv:2686 John Wiley & Sons, Ltd [cited 2019 Aug 15]. Available from: https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/erv.2686.","journal-title":"Eur Eat Disord Rev"},{"key":"3497_CR39","doi-asserted-by":"publisher","first-page":"637","DOI":"10.2147\/NDT.S73239","volume":"11","author":"M Bomba","year":"2015","unstructured":"Bomba M, Riva A, Morzenti S, Grimaldi M, Neri F, Nacinovich R. Global and regional brain volumes normalization in weight-recovered adolescents with anorexia nervosa: preliminary findings of a longitudinal voxel-based morphometry study. Neuropsychiatr Dis Treat. 2015;11:637\u201345 Dove Press [cited 2016 Apr 6]. Available from: https:\/\/www.dovepress.com\/global-and-regional-brain-volumes-normalization-in-weight-recovered-ad-peer-reviewed-article-NDT.","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"1","key":"3497_CR40","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.pscychresns.2010.06.007","volume":"191","author":"S Gaudio","year":"2011","unstructured":"Gaudio S, Nocchi F, Franchin T, Genovese E, Cannat\u00e0 V, Longo D, et al. Gray matter decrease distribution in the early stages of Anorexia Nervosa restrictive type in adolescents. Psychiatry Res Neuroimaging. 2011;191(1):24\u201330 [cited 2016 Feb 23]. Available from: http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0925492710002258.","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"6","key":"3497_CR41","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1097\/YCO.0000000000000544","volume":"32","author":"GKW Frank","year":"2019","unstructured":"Frank GKW. Neuroimaging and eating disorders. Curr Opin Psychiatry. 2019;32(6):478\u201383. Available from: https:\/\/journals.lww.com\/co-psychiatry\/FullText\/2019\/11000\/Neuroimaging_and_eating_disorders.3.aspx?casa_token=VEX2QbaEiLUAAAAA:9FJr-DqtVxtYIB9WsnCfhXpYKQYgvFhjUtYjIm9SFlnS550bVdgfI5s3TS7zUBDMwf62h8d3wdfTToSoTMyb8mBdDUDb5PARoQ. https:\/\/doi.org\/10.1097\/YCO.0000000000000544.","journal-title":"Curr Opin Psychiatry"},{"key":"3497_CR42","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.pscychresns.2018.08.009","volume":"281","author":"L Yue","year":"2018","unstructured":"Yue L, Wang Y, Kaye WH, Kang Q, Bin HJ, EFC C, et al. Structural alterations in the caudate nucleus and precuneus in un-medicated anorexia nervosa patients. Psychiatry Res \u2013 Neuroimaging. 2018;281:12\u20138 Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0925492718300969?casa_token=rUw-FULXoPMAAAAA:opFoX4oNB0a9EM-OBvrSvP0RYqPNCs7kgIwl0Jy57UmcTT_JjSCsyF2_-L3QyfjvtVokAM3elxw4.","journal-title":"Psychiatry Res \u2013 Neuroimaging"},{"issue":"5","key":"3497_CR43","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1002\/hbm.22736","volume":"36","author":"S Ehrlich","year":"2015","unstructured":"Ehrlich S, Lord AR, Geisler D, Borchardt V, Boehm I, Seidel M, et al. Reduced functional connectivity in the thalamo-insular subnetwork in patients with acute anorexia nervosa. Hum Brain Mapp. 2015;36(5):1772\u201381 Available from: http:\/\/doi.wiley.com\/10.1002\/hbm.22736.","journal-title":"Hum Brain Mapp"},{"issue":"1","key":"3497_CR44","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1503\/jpn.140310","volume":"41","author":"D Geisler","year":"2016","unstructured":"Geisler D, Borchardt V, Lord AR, Boehm I, Ritschel F, Zwipp J, et al. Abnormal functional global and local brain connectivity in female patients with anorexia nervosa. J Psychiatry Neurosci. 2016;41(1):6\u201315 Canadian Medical Association; [cited 2018 may 29]. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26252451.","journal-title":"J Psychiatry Neurosci"},{"key":"3497_CR45","doi-asserted-by":"publisher","first-page":"117769","DOI":"10.1016\/j.neuroimage.2021.117769","volume":"229","author":"Z Gracia-Tabuenca","year":"2021","unstructured":"Gracia-Tabuenca Z, Moreno MB, Barrios FA, Alcauter S. Development of the brain functional connectome follows puberty-dependent nonlinear trajectories. Neuroimage. 2021;229:117769 Academic Press Inc.; [cited 2021 Apr 5]. Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S105381192100046X.","journal-title":"Neuroimage"},{"issue":"8","key":"3497_CR46","doi-asserted-by":"publisher","first-page":"1907","DOI":"10.3390\/nu11081907","volume":"11","author":"G Olivo","year":"2019","unstructured":"Olivo G, Gaudio S, Schi\u00f6th HB. Brain and Cognitive Development in Adolescents with Anorexia Nervosa: A Systematic Review of fMRI Studies. Nutrients. 2019;11(8):1907 MDPI AG; [cited 2020 Aug 14]. Available from: https:\/\/www.mdpi.com\/2072-6643\/11\/8\/1907.","journal-title":"Nutrients"},{"key":"3497_CR47","doi-asserted-by":"crossref","unstructured":"Boehm I, Geisler D, Tam F, King JA, Ritschel F, Seidel M, et al. Partially restored resting-state functional connectivity in women recovered from anorexia nervosa. J Psychiatry Neurosci. 2016;41(6) Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5082508\/.","DOI":"10.1503\/jpn.150259"},{"key":"3497_CR48","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.neuroimage.2016.02.003","volume":"130","author":"F Bernardoni","year":"2016","unstructured":"Bernardoni F, King JA, Geisler D, Stein E, Jaite C, N\u00e4tsch D, et al. Weight restoration therapy rapidly reverses cortical thinning in anorexia nervosa: A longitudinal study. Neuroimage. 2016;130:214\u201322 Academic Press; [cited 2018 Apr 9]. Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1053811916001014.","journal-title":"Neuroimage"},{"issue":"12","key":"3497_CR49","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1016\/S2215-0366(15)00356-9","volume":"2","author":"S Zipfel","year":"2015","unstructured":"Zipfel S, Giel KE, Bulik CM, Hay P, Schmidt U. Anorexia nervosa: aetiology, assessment, and treatment. Lancet Psychiatry. 2015;2(12):1099\u2013111. Elsevier Ltd; Available from: https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2215036615003569. https:\/\/doi.org\/10.1016\/S2215-0366(15)00356-9.","journal-title":"Lancet Psychiatry"},{"issue":"3","key":"3497_CR50","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.biopsych.2017.08.011","volume":"83","author":"JA King","year":"2018","unstructured":"King JA, Frank GKW, Thompson PM, Ehrlich S. Structural Neuroimaging of Anorexia Nervosa: Future Directions in the Quest for Mechanisms Underlying Dynamic Alterations. Biol Psychiatry. 2018;83(3):224\u201334 Elsevier; [cited 2019 Mar 18] Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S000632231731898X?via%3Dihub.","journal-title":"Biol Psychiatry"},{"key":"3497_CR51","doi-asserted-by":"publisher","unstructured":"Lotter LD, von Polier G, Offermann J, Buettgen K, Stanetzky L, Eickhoff SB, et al. Recovery-associated resting-state activity and connectivity alterations in Anorexia nervosa. Biol Psychiatry Cogn Neurosci Neuroimaging [Internet]. Elsevier Inc. 2021;(22). Available from: https:\/\/doi.org\/10.1016\/j.bpsc.2021.03.006.","DOI":"10.1016\/j.bpsc.2021.03.006"}],"container-title":["BMC Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12888-021-03497-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12888-021-03497-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12888-021-03497-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T02:30:53Z","timestamp":1633573853000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpsychiatry.biomedcentral.com\/articles\/10.1186\/s12888-021-03497-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,6]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["3497"],"URL":"https:\/\/doi.org\/10.1186\/s12888-021-03497-4","relation":{},"ISSN":["1471-244X"],"issn-type":[{"value":"1471-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,6]]},"assertion":[{"value":"12 April 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 September 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 October 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Norwegian Committee for Medical and Health Research Ethics (REC), North region (protocol number 302969). Informed consent was obtained from participants and parents in the case of participants below 16\u2009years of age. All methods used in the present study were performed in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no conflict to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"490"}}