{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T01:44:42Z","timestamp":1769478282072,"version":"3.49.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T00:00:00Z","timestamp":1766448000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Psychiatry"],"DOI":"10.1186\/s12888-025-07722-2","type":"journal-article","created":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T13:45:10Z","timestamp":1766497510000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of childhood trauma on depressive symptoms in bipolar adolescents: the mediating effect of sleep disturbance"],"prefix":"10.1186","volume":"26","author":[{"given":"Zhiying","family":"Wan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanfang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongchun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiyu","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofen","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,23]]},"reference":[{"issue":"4","key":"7722_CR1","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1136\/eb-2018-102912","volume":"21","author":"RL Findling","year":"2018","unstructured":"Findling RL, Stepanova E, Youngstrom EA, Young AS. Progress in diagnosis and treatment of bipolar disorder among children and adolescents: an international perspective. Evid Based Ment Health. 2018;21(4):177\u201381. https:\/\/doi.org\/10.1136\/eb-2018-102912.","journal-title":"Evid Based Ment Health"},{"issue":"11","key":"7722_CR2","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1016\/j.jaac.2024.05.007","volume":"63","author":"EN Tu","year":"2024","unstructured":"Tu EN, Duffy A. Editorial: combining genetic and clinical predictors of bipolar disorder: towards improving diagnostic precision in youth. J Am Acad Child Adolesc Psychiatry. 2024;63(11):1081\u20133. https:\/\/doi.org\/10.1016\/j.jaac.2024.05.007.","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"9","key":"7722_CR3","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1016\/j.biopsych.2004.01.022","volume":"55","author":"RH Perlis","year":"2004","unstructured":"Perlis RH, Miyahara S, Marangell LB, Wisniewski SR, Ostacher M, DelBello MP, Bowden CL, Sachs GS, Nierenberg AA, STEP-BD, Investigators. Long-term implications of early onset in bipolar disorder: data from the first 1000 participants in the systematic treatment enhancement program for bipolar disorder (STEP-BD). Biol Psychiatry. 2004;55(9):875\u201381. https:\/\/doi.org\/10.1016\/j.biopsych.2004.01.022.","journal-title":"Biol Psychiatry"},{"issue":"1","key":"7722_CR4","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1186\/s12888-025-06748-w","volume":"25","author":"F Chen","year":"2025","unstructured":"Chen F, Chen C, Wu M, Luo B, Cai H, Yu F, Wang L. Impaired emotional response Inhibition among adolescents with bipolar depression: evidence from event-related potentials and behavioral performance. BMC Psychiatry. 2025;25(1):303. https:\/\/doi.org\/10.1186\/s12888-025-06748-w.","journal-title":"BMC Psychiatry"},{"issue":"Suppl 1","key":"7722_CR5","doi-asserted-by":"publisher","first-page":"S59","DOI":"10.1016\/j.jad.2004.05.013","volume":"82","author":"J Wozniak","year":"2004","unstructured":"Wozniak J, Spencer T, Biederman J, Kwon A, Monuteaux M, Rettew J, Lail K. The clinical characteristics of unipolar vs. bipolar major depression in ADHD youth. J Affect Disord. 2004;82(Suppl 1):S59\u201369. https:\/\/doi.org\/10.1016\/j.jad.2004.05.013.","journal-title":"J Affect Disord"},{"key":"7722_CR6","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.jpsychires.2017.07.027","volume":"95","author":"IH Stanley","year":"2017","unstructured":"Stanley IH, Hom MA, Luby JL, Joshi PT, Wagner KD, Emslie GJ, Walkup JT, Axelson DA, Joiner TE. Comorbid sleep disorders and suicide risk among children and adolescents with bipolar disorder. J Psychiatr Res. 2017;95:54\u20139. https:\/\/doi.org\/10.1016\/j.jpsychires.2017.07.027.","journal-title":"J Psychiatr Res"},{"issue":"4","key":"7722_CR7","doi-asserted-by":"publisher","first-page":"312","DOI":"10.4103\/0019-5545.91904","volume":"53","author":"A Ratheesh","year":"2011","unstructured":"Ratheesh A, Srinath S, Reddy YC, Girimaji SC, Seshadri SP, Thennarasu K, Hutin Y. Are anxiety disorders associated with a more severe form of bipolar disorder in adolescents? Indian J Psychiatry. 2011;53(4):312\u20138. https:\/\/doi.org\/10.4103\/0019-5545.91904.","journal-title":"Indian J Psychiatry"},{"issue":"4","key":"7722_CR8","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1016\/S2215-0366(15)00544-1","volume":"3","author":"J Agnew-Blais","year":"2016","unstructured":"Agnew-Blais J, Danese A. Childhood maltreatment and unfavourable clinical outcomes in bipolar disorder: a systematic review and meta-analysis. Lancet Psychiatry. 2016;3(4):342\u20139. https:\/\/doi.org\/10.1016\/S2215-0366(15)00544-1.","journal-title":"Lancet Psychiatry"},{"issue":"3","key":"7722_CR9","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1111\/acps.13528","volume":"147","author":"AL Wrobel","year":"2023","unstructured":"Wrobel AL, Cotton SM, Jayasinghe A, Diaz-Byrd C, Yocum AK, Turner A, Dean OM, Russell SE, Duval ER, Ehrlich TJ, Marshall DF, Berk M, McInnis MG. Childhood trauma and depressive symptoms in bipolar disorder: A network analysis. Acta Psychiatr Scand. 2023;147(3):286\u2013300. https:\/\/doi.org\/10.1111\/acps.13528.","journal-title":"Acta Psychiatr Scand"},{"issue":"14","key":"7722_CR10","doi-asserted-by":"publisher","first-page":"2346","DOI":"10.1017\/S0033291719002411","volume":"50","author":"S Marwaha","year":"2020","unstructured":"Marwaha S, Briley PM, Perry A, Rankin P, DiFlorio A, Craddock N, Jones I, Broome M, Gordon-Smith K, Jones L. Explaining why childhood abuse is a risk factor for poorer clinical course in bipolar disorder: a path analysis of 923 people with bipolar I disorder. Psychol Med. 2020;50(14):2346\u201354. https:\/\/doi.org\/10.1017\/S0033291719002411.","journal-title":"Psychol Med"},{"issue":"1","key":"7722_CR11","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.1192\/j.eurpsy.2025.2452","volume":"68","author":"V Baldini","year":"2025","unstructured":"Baldini V, Gottardi C, Di Stefano R, Rindi LV, Pazzocco G, Varallo G, Purgato M, De Ronchi D, Barbui C, Ostuzzi G. Association between adverse childhood experiences and suicidal behavior in affective disorders: A systematic review and meta-analysis. Eur Psychiatry. 2025;68(1):e58. https:\/\/doi.org\/10.1192\/j.eurpsy.2025.2452.","journal-title":"Eur Psychiatry"},{"issue":"2","key":"7722_CR12","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1177\/00332941241269549","volume":"128","author":"U Tak\u0131m","year":"2025","unstructured":"Tak\u0131m U, Sar\u0131 S, Gokcay H. The relationship between childhood traumas and social cognition through theory of Mind and alexithymia in bipolar disorder. Psychol Rep. 2025;128(2):800\u201315. https:\/\/doi.org\/10.1177\/00332941241269549.","journal-title":"Psychol Rep"},{"issue":"5","key":"7722_CR13","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.sleh.2022.06.008","volume":"8","author":"CH Oh","year":"2022","unstructured":"Oh CH, Wallace ML, Germain A. Childhood trauma and gender: synergistic and additive effects on sleep in healthy young adults. Sleep Health. 2022;8(5):498\u2013504. https:\/\/doi.org\/10.1016\/j.sleh.2022.06.008.","journal-title":"Sleep Health"},{"key":"7722_CR14","doi-asserted-by":"publisher","first-page":"101621","DOI":"10.1016\/j.smrv.2022.101621","volume":"64","author":"SM Brown","year":"2022","unstructured":"Brown SM, Rodriguez KE, Smith AD, Ricker A, Williamson AA. Associations between childhood maltreatment and behavioral sleep disturbances across the lifespan: A systematic review. Sleep Med Rev. 2022;64:101621. https:\/\/doi.org\/10.1016\/j.smrv.2022.101621.","journal-title":"Sleep Med Rev"},{"key":"7722_CR15","doi-asserted-by":"publisher","first-page":"102137","DOI":"10.1016\/j.smrv.2025.102137","volume":"83","author":"M Marchetti","year":"2025","unstructured":"Marchetti M, Mayeli A, Sanguineti C, Donati FL, Chaichian O, Kim A, Piskun K, D\u2019Agostino A, Meyer N, Wilson JD, Fusar-Poli P, Phillips ML, Ferrarelli F. Sleep abnormalities in bipolar disorders across mood phases: A systematic review and meta-analysis. Sleep Med Rev. 2025;83:102137. https:\/\/doi.org\/10.1016\/j.smrv.2025.102137.","journal-title":"Sleep Med Rev"},{"issue":"4","key":"7722_CR16","doi-asserted-by":"publisher","first-page":"e247532","DOI":"10.1001\/jamanetworkopen.2024.7532","volume":"7","author":"EL Olsen","year":"2024","unstructured":"Olsen EL, April-Sanders AK, Bird HR, Canino GJ, Duarte CS, Suglia SF. Adverse childhood experiences and sleep disturbances among Puerto Rican young adults. JAMA Netw Open. 2024;7(4):e247532. https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.7532.","journal-title":"JAMA Netw Open"},{"key":"7722_CR17","doi-asserted-by":"publisher","first-page":"101628","DOI":"10.1016\/j.smrv.2022.101628","volume":"64","author":"R Langevin","year":"2022","unstructured":"Langevin R, Kenny S, Kern A, Kingsland E, Pennestri MH. Sexual abuse and sleep in children and adolescents: a systematic review. Sleep Med Rev. 2022;64:101628. https:\/\/doi.org\/10.1016\/j.smrv.2022.101628.","journal-title":"Sleep Med Rev"},{"issue":"5","key":"7722_CR18","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1111\/bdi.13429","volume":"26","author":"L Basquin","year":"2024","unstructured":"Basquin L, Maruani J, Leseur J, Mauries S, Bazin B, Pineau G, Henry C, Lejoyeux M, Geoffroy PA. Study of the different sleep disturbances during the prodromal phase of depression and mania in bipolar disorders. Bipolar Disord. 2024;26(5):454\u201367. https:\/\/doi.org\/10.1111\/bdi.13429.","journal-title":"Bipolar Disord"},{"issue":"5","key":"7722_CR19","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.jadohealth.2019.12.005","volume":"66","author":"A Goldstone","year":"2020","unstructured":"Goldstone A, Javitz HS, Claudatos SA, Buysse DJ, Hasler BP, de Zambotti M, Clark DB, Franzen PL, Prouty DE, Colrain IM, Baker FC. Sleep disturbance predicts depression symptoms in early adolescence: initial findings from the adolescent brain cognitive development study. J Adolesc Health. 2020;66(5):567\u201374. https:\/\/doi.org\/10.1016\/j.jadohealth.2019.12.005.","journal-title":"J Adolesc Health"},{"issue":"12","key":"7722_CR20","doi-asserted-by":"publisher","first-page":"112601","DOI":"10.5498\/wjp.v15.i12.112601","volume":"15","author":"U Takim","year":"2025","unstructured":"Takim U, Gokcay H, Sa\u011flam T. Evaluation of sleep quality in patients diagnosed with bipolar disorder and major depression during remission period. World J Psychiatry. 2025;15(12):112601. https:\/\/doi.org\/10.5498\/wjp.v15.i12.112601.","journal-title":"World J Psychiatry"},{"issue":"2","key":"7722_CR21","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1002\/wps.20049","volume":"12","author":"Mario Maj","year":"2013","unstructured":"Mario Maj. Clinical judgment and the DSM-5 diagnosis of major depression. World Psychiatry. 2013;12(2):89\u201391. https:\/\/doi.org\/10.1002\/wps.20049.","journal-title":"World Psychiatry"},{"issue":"20","key":"7722_CR22","first-page":"105","volume":"9","author":"Z Zhao Xingfu","year":"2005","unstructured":"Zhao Xingfu Z, Yalin, Li longfei, Yunfei Z, Hezhan L. Yang Shichang. Reliability and validity of the Chinese version of childhood trauma questionnaire. Zhongguo Linchuang Kangfu. 2005;9(20):105\u20137.","journal-title":"Zhongguo Linchuang Kangfu"},{"issue":"2","key":"7722_CR23","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/s0145-2134(02)00541-0","volume":"27","author":"DP Bernstein","year":"2003","unstructured":"Bernstein DP, Stein JA, Newcomb MD, Walker E, Pogge D, Ahluvalia T, Stokes J, Handelsman L, Medrano M, Desmond D, Zule W. Development and validation of a brief screening version of the childhood trauma questionnaire. Child Abuse Negl. 2003;27(2):169\u201390. https:\/\/doi.org\/10.1016\/s0145-2134(02)00541-0.","journal-title":"Child Abuse Negl"},{"key":"7722_CR24","doi-asserted-by":"publisher","unstructured":"Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193\u2013213. https:\/\/doi.org\/10.1016\/0165-1781(89)90047-4.","DOI":"10.1016\/0165-1781(89)90047-4"},{"issue":"2","key":"7722_CR25","first-page":"103","volume":"29","author":"T Liu Xianchen","year":"1996","unstructured":"Liu Xianchen T, Maoqin H, Lei W, Aizhen W, Hongxin Z, Guifang. Gao Chunni, Li Wanshun. Reliability and validity of Pittsburgh sleep quality index. Chin J Psychiatry. 1996;29(2):103\u20137.","journal-title":"Chin J Psychiatry"},{"issue":"18","key":"7722_CR26","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1001\/jama.282.18.1737","volume":"282","author":"RL Spitzer","year":"1999","unstructured":"Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary care evaluation of mental disorders. Patient Health Questionnaire JAMA. 1999;282(18):1737\u201344. https:\/\/doi.org\/10.1001\/jama.282.18.1737.","journal-title":"Patient Health Questionnaire JAMA"},{"issue":"2","key":"7722_CR27","doi-asserted-by":"publisher","first-page":"292","DOI":"10.62641\/aep.v53i2.1690","volume":"53","author":"B Wang","year":"2025","unstructured":"Wang B, Zhang J, Cao C, Xu L, Gao M, Zhang Q, Zhang K. The relationship between childhood trauma and depression in early adulthood: the roles of resilience and personality type. Actas Esp Psiquiatr. 2025;53(2):292\u2013303. https:\/\/doi.org\/10.62641\/aep.v53i2.1690.","journal-title":"Actas Esp Psiquiatr"},{"key":"7722_CR28","doi-asserted-by":"publisher","unstructured":"Zhou L, Yao N, Zengxu Z, Wu B, Liu M. The relationship between childhood trauma and depressive symptoms: the serial mediation role of ruminative thinking and prospective imagery vividness. Psychol Health Med. 2025:1\u201314. https:\/\/doi.org\/10.1080\/13548506.2025.2519236.","DOI":"10.1080\/13548506.2025.2519236"},{"issue":"4","key":"7722_CR29","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1007\/s00406-024-01847-3","volume":"275","author":"Y Liu","year":"2025","unstructured":"Liu Y, Jing Y, Gao Y, Li M, Qin W, Xie Y, Zhang B, Li J. Exploring the correlation between childhood trauma experiences, inflammation, and brain activity in first-episode, drug-naive major depressive disorder. Eur Arch Psychiatry Clin Neurosci. 2025;275(4):1063\u201374. https:\/\/doi.org\/10.1007\/s00406-024-01847-3.","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"issue":"1","key":"7722_CR30","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1186\/s12888-024-06226-9","volume":"24","author":"M Wang","year":"2024","unstructured":"Wang M, Wei J, Dou Y, Wang Y, Fan H, Yan Y, Du Y, Zhao L, Wang Q, Yang X, Ma X. Differential association between childhood trauma subtypes and neurocognitive performance in adults with major depression. BMC Psychiatry. 2024;24(1):773. https:\/\/doi.org\/10.1186\/s12888-024-06226-9.","journal-title":"BMC Psychiatry"},{"key":"7722_CR31","doi-asserted-by":"publisher","first-page":"104488","DOI":"10.1016\/j.actpsy.2024.104488","volume":"250","author":"V Karatzoglou","year":"2024","unstructured":"Karatzoglou V, Carollo A, Karagiannopoulou E, Esposito G, S\u00e9aghdha XT\u00d3, Dimitriou D. A scientometric review of the association between childhood trauma and sleep. Acta Psychol (Amst). 2024;250:104488. https:\/\/doi.org\/10.1016\/j.actpsy.2024.104488.","journal-title":"Acta Psychol (Amst)"},{"issue":"4","key":"7722_CR32","doi-asserted-by":"publisher","first-page":"zsae281","DOI":"10.1093\/sleep\/zsae281","volume":"48","author":"M Zarchev","year":"2025","unstructured":"Zarchev M, Kamperman AM, Hoepel SJW, Hoogendijk WJG, Mulder CL, Grootendorst-van Mil NH. The association between childhood maltreatment and multidimensional sleep health in adolescents at high risk of emotional and behavioral problems. Sleep. 2025;48(4):zsae281. https:\/\/doi.org\/10.1093\/sleep\/zsae281.","journal-title":"Sleep"},{"issue":"10","key":"7722_CR33","doi-asserted-by":"publisher","first-page":"108","DOI":"10.3390\/bs9100108","volume":"9","author":"SKR Baddam","year":"2019","unstructured":"Baddam SKR, Olvera RL, Canapari CA, Crowley MJ, Williamson DE. Childhood trauma and stressful life events are independently associated with sleep disturbances in adolescents. Behav Sci (Basel). 2019;9(10):108. https:\/\/doi.org\/10.3390\/bs9100108.","journal-title":"Behav Sci (Basel)"},{"issue":"1","key":"7722_CR34","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1186\/s12889-025-21621-x","volume":"25","author":"T Coote","year":"2025","unstructured":"Coote T, Barrett E, Grummitt L. Sleep duration in adolescence buffers the impact of childhood trauma on anxiety and depressive symptoms. BMC Public Health. 2025;25(1):437. https:\/\/doi.org\/10.1186\/s12889-025-21621-x.","journal-title":"BMC Public Health"},{"key":"7722_CR35","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleh.2016.03.001","author":"TS Hall Brown","year":"2016","unstructured":"Hall Brown TS, Belcher HME, Accardo J, Minhas R, Briggs EC. Sleep Health. 2016;2(2):123\u20138. https:\/\/doi.org\/10.1016\/j.sleh.2016.03.001. Trauma exposure and sleep disturbance in a sample of youth from the National Child Traumatic Stress Network Core Data Set."},{"issue":"2","key":"7722_CR36","doi-asserted-by":"publisher","first-page":"27","DOI":"10.5498\/wjp.v11.i2.27","volume":"11","author":"G Giannakopoulos","year":"2021","unstructured":"Giannakopoulos G, Kolaitis G. Sleep problems in children and adolescents following traumatic life events. World J Psychiatry. 2021;11(2):27\u201334. https:\/\/doi.org\/10.5498\/wjp.v11.i2.27.","journal-title":"World J Psychiatry"},{"key":"7722_CR37","doi-asserted-by":"publisher","first-page":"993284","DOI":"10.3389\/fpsyt.2022.993284","volume":"13","author":"B Luo","year":"2022","unstructured":"Luo B, Yang Y, Zhang D, Zhang Q, Liu Z, Wang S, Shi Y, Xia L, Wang J, Liu Z, Geng F, Chen C, Wen X, Luo X, Zhang K, Liu H. Sleep disorders mediate the link between childhood trauma and depression severity in children and adolescents with depression. Front Psychiatry. 2022;13:993284. https:\/\/doi.org\/10.3389\/fpsyt.2022.993284.","journal-title":"Front Psychiatry"},{"issue":"1","key":"7722_CR38","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/s13034-023-00635-6","volume":"17","author":"W Guo","year":"2023","unstructured":"Guo W, Zhao Y, Chen H, Liu J, Chen X, Tang H, Zhou J, Wang X. The Bridge symptoms of childhood trauma, sleep disorder and depressive symptoms: a network analysis. Child Adolesc Psychiatry Ment Health. 2023;17(1):88. https:\/\/doi.org\/10.1186\/s13034-023-00635-6.","journal-title":"Child Adolesc Psychiatry Ment Health"},{"issue":"5","key":"7722_CR39","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1017\/S0033291716003081","volume":"47","author":"M Aas","year":"2017","unstructured":"Aas M, Henry C, Bellivier F, Lajnef M, Gard S, Kahn JP, Lagerberg TV, Aminoff SR, Bjella T, Leboyer M, Andreassen OA, Melle I, Etain B. Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders. Psychol Med. 2017;47(5):902\u201312. https:\/\/doi.org\/10.1017\/S0033291716003081.","journal-title":"Psychol Med"},{"issue":"1","key":"7722_CR40","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1186\/s12888-021-03194-2","volume":"21","author":"F Cui","year":"2021","unstructured":"Cui F, Liu Q, Lv X, Leonhart R, Tian H, Wei J, Zhang K, Zhu G, Chen Q, Wang G, Wang X, Zhang N, Huang Y, Si T, Yu X. Severe sleep disturbance is associated with executive function impairment in patients with first-episode, treatment-na\u00efve major depressive disorders. BMC Psychiatry. 2021;21(1):198. https:\/\/doi.org\/10.1186\/s12888-021-03194-2.","journal-title":"BMC Psychiatry"},{"issue":"2","key":"7722_CR41","doi-asserted-by":"publisher","first-page":"214","DOI":"10.3390\/brainsci15020214","volume":"15","author":"L Piccirilli","year":"2025","unstructured":"Piccirilli L, Capuzzi E, Legnani F, Di Paolo M, Pan A, Ceresa A, Esposito CM, Cirella L, Surace T, Tagliabue I, Clerici M, Buoli M. Gender differences in clinical and biochemical variables of patients affected by bipolar disorder. Brain Sci. 2025;15(2):214. https:\/\/doi.org\/10.3390\/brainsci15020214.","journal-title":"Brain Sci"},{"issue":"1","key":"7722_CR42","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1186\/s40359-024-02236-0","volume":"12","author":"Z Ye","year":"2024","unstructured":"Ye Z, Zhang F, Cui R, Ye X, Tan M, Tao T, Zhang X. The effect of depression on non-suicidal self-injury and psychological status in adolescents with unipolar and bipolar disorders. BMC Psychol. 2024;12(1):743. https:\/\/doi.org\/10.1186\/s40359-024-02236-0.","journal-title":"BMC Psychol"}],"container-title":["BMC Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12888-025-07722-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12888-025-07722-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12888-025-07722-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T15:33:36Z","timestamp":1769441616000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12888-025-07722-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,23]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["7722"],"URL":"https:\/\/doi.org\/10.1186\/s12888-025-07722-2","relation":{"references":[{"id-type":"doi","id":"10.1016\/j.sleh.2016.03.001","asserted-by":"subject"}]},"ISSN":["1471-244X"],"issn-type":[{"value":"1471-244X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,23]]},"assertion":[{"value":"27 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in strict adherence to the ethical principles delineated in the Declaration of Helsinki., and approved by the Ethics Committee of Renmin Hospital of Wuhan University (Number: WDRY2025-K017). Written informed consent was obtained from all parents or legal guardians, and written assent was secured from all adolescent participants, underscoring the voluntary nature of their involvement.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"70"}}