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The summary statistics for metabolites and AD did not contain any personal information, and the GWAS have obtained ethical approval from relevant ethics review boards. Written consent to be enrolled in the databases was obtained from study participants, or for those with substantial cognitive decline, from a caregiver, legal guardian, or other proxy by each original GWAS study. Patient consents for the current analysis were waived because of the retrospective nature of the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"L.W. provided consulting service to Pupil Bio Inc.,Techspert, and Galiher DeRobertis & Waxman LLP, and reviewed manuscriptsfor\n                      Gastroenterology Report\n                      , notrelated to this study, and received honoraria. No potential conflicts of interest were disclosed by the other authors.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"491"}}