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Research to date has primarily sought to identify the risk factors affecting students\u2019 mental health; however, their exposure to these factors is often unavoidable. Thus, the present study adopted a salutogenic approach focussing on the determinants of health. We examined the mental health resources available to students reported in the literature as being susceptible to helping them maintain good mental health despite their exposure to risk factors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In February 2020, 2,415 first- and second-year bachelor\u2019s degree students in applied sciences in French-speaking Switzerland completed an online questionnaire. The variables measured were self-evaluated mental health, perceived stress and three potential health resources: students\u2019 feelings of self-efficacy, their capacity for mindfulness and their social support. The results were analysed using hierarchical linear regression models.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>When all the variables were included in the model without interaction effect, our results revealed that students\u2019 self-evaluated mental health was negatively associated with perceived stress (\u03b2\u2009=\u2009-0.43, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and positively associated with the three potential health resources (self-efficacy: \u03b2\u2009=\u20090.26, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; mindfulness: \u03b2\u2009=\u20090.10, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; social support: \u03b2\u2009=\u20090.17, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). An analysis of the interaction effects also revealed that a high level of self-efficacy was associated with perceived stress being less strongly linked to mental health (\u03b2\u2009=\u20090.29, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>These findings suggest that self-efficacy, mindfulness, and perceived social support are valuable resources for protecting students\u2019 mental health. Thus, implementing interventions aimed at reinforcing them, could support students in applied sciences all along their academic pathway, in their classes and during their professional work experience placements.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12889-024-17692-x","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T11:02:22Z","timestamp":1706698942000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Self-efficacy, mindfulness, and perceived social support as resources to maintain the mental health of students in Switzerland\u2019s universities of applied sciences: a cross-sectional study"],"prefix":"10.1186","volume":"24","author":[{"given":"Myriam","family":"Guzman Villegas-Frei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Jubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Ortoleva","family":"Bucher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie Oulevey","family":"Bachmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,31]]},"reference":[{"key":"17692_CR1","unstructured":"World Health Organization. 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