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The purpose of this study was to identify of nutrient deficiencies patterns and analyze their potential impact on mortality risk in older adults with hypertension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included participants from the National Health and Nutrition Examination Survey (NHANES) study. The latent class analysis (LCA) was applied to uncover specific malnutrition profiles within the sample. Risk of the end points across the phenogroups was compared using Kaplan\u2013Meier analysis and Cox proportional hazard regression model. Multinomial logistic regression was used to determine the influencing factors of specific malnutrition profiles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 6924 participants aged 60\u00a0years or older with hypertension from NHANES 2003\u20132014 was followed until December 31, 2019 with a median follow-up of 8.7\u00a0years. Various nutrients included vitamin A, vitamin B1, vitamin B12, vitamin C, vitamin D, vitamin E, vitamin K, fiber, folate, calcium, magnesium, zinc, copper, iron, and selenium, and LCA revealed 4 classes of malnutrition. Regarding all-cause mortality, \u201cNutrient Deprived\u201d group showed the strongest hazard ratio (1.42 from 1.19 to 1.70) compared with \u201cAdequate Nutrient\u201d group, followed by \u201cInadequate Nutrient\u201d group (1.29 from 1.10 to 1.50), and \u201cLow Fiber, Magnesium, and Vit E\u201d group (1.17 from 1.02 to 1.35). For cardiovascular mortality, \u201cNutrient Deprived\u201d group showed the strongest hazard ratio (1.61 from 1.19 to 2.16) compared with \u201cAdequate Nutrient\u201d group, followed by \u201cLow Fiber, Magnesium, and Vit E\u201d group (1.51 from 1.04 to 2.20), and \u201cInadequate Nutrient\u201d group (1.37 from 1.03 to 1.83).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study revealed a significant association between nutrients deficiency patterns and the risk of all-cause and cardiovascular mortality in older adults with hypertension. The findings suggested that nutrients deficiency pattern may be an important risk factor for mortality in older adults with hypertension.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12889-024-19003-w","type":"journal-article","created":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T21:02:09Z","timestamp":1717966929000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Nutrient deficiency patterns and all-cause and cardiovascular mortality in older adults with hypertension: a latent class analysis"],"prefix":"10.1186","volume":"24","author":[{"given":"YuJiao","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HuanRui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GuoXian","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,10]]},"reference":[{"key":"19003_CR1","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1001\/jama.294.4.466","volume":"294","author":"DM Lloyd-Jones","year":"2005","unstructured":"Lloyd-Jones DM, Evans JC, Levy D. 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