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None of the support received relates to the submitted work.Juan Francisco Hernandez carried out the systematic review as an employee of Pharmerit, with funding from Bayer AG.Roland Diel reports personal fees from Bayer, INSMED and Riemser Pharma. None of the support received relates to the submitted work.Anna Filonenko is an employee of Bayer AG.Rowena Hughes reports personal fees from highfield:communication for medical writing services.Fabian Juelich is an employee of Bayer Vital GmbH.George Solomon has nothing to disclose.Alex Upton is an employee of Bayer plc.Kamonthip Wichmann is an employee of Bayer AG.Weiwei Xu carried out the systematic review as an employee of Pharmerit, with funding from Bayer AG.James D Chalmers reports fees from Bayer Healthcare, during the conduct of the study; grants and personal fees from GlaxoSmithKline, Boehringer Ingelheim, Pfizer, Bayer Healthcare and Grifols, grants from AstraZeneca, and personal fees from Napp. None of the support received relates to the submitted work.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"54"}}