{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T13:01:55Z","timestamp":1784034115379,"version":"3.55.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T00:00:00Z","timestamp":1558656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T00:00:00Z","timestamp":1558656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pulm Med"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12890-019-0854-2","type":"journal-article","created":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T11:02:43Z","timestamp":1558695763000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Factors affecting survival in patients with endobronchial malignant mass after flexible Bronchoscopic cryotherapy: a cohort study"],"prefix":"10.1186","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9749-0111","authenticated-orcid":false,"given":"Fu-Tsai","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Liang","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Lun","family":"Lo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hsi","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsai-Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Hwa","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horng-Chyuan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hao","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung-Shu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Cheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Min","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,24]]},"reference":[{"key":"854_CR1","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1164\/rccm.200210-1181SO","volume":"169","author":"A Ernst","year":"2004","unstructured":"Ernst A, Feller-Kopman D, Becker HD, Mehta AC. Central airway obstruction. Am J Respir Crit Care Med. 2004;169:1278\u201397.","journal-title":"Am J Respir Crit Care Med"},{"key":"854_CR2","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/j.chest.2016.02.001","volume":"150","author":"SD Murgu","year":"2016","unstructured":"Murgu SD, Egressy K, Laxmanan B, et al. Central Airway Obstruction: Benign Strictures, Tracheobronchomalacia, and Malignancy-relatedObstruction. Chest. 2016;150:426\u201341.","journal-title":"Chest"},{"key":"854_CR3","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1378\/chest.14-1526","volume":"147","author":"DE Ost","year":"2015","unstructured":"Ost DE, Ernst A, Grosu HB, Lei X, et al. SimoffM; AQuIRE bronchoscopy registry. Therapeutic bronchoscopy for malignant centralairway obstruction: success rates and impact on dyspnea and quality of life. Chest. 2015;147:1282\u201398.","journal-title":"Chest"},{"key":"854_CR4","first-page":"S363","volume":"7","author":"A Sachdeva","year":"2015","unstructured":"Sachdeva A, Pickering EM, Lee HJ. From electrocautery, balloon dilatation, neodymium-doped:yttrium-aluminum-garnet (Nd:YAG) laser to argon plasma coagulation and cryotherapy. J Thorac Dis. 2015;7:S363\u201379.","journal-title":"J Thorac Dis"},{"key":"854_CR5","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1378\/chest.112.1.202","volume":"112","author":"HG Colt","year":"1997","unstructured":"Colt HG, Harrell JH. Therapeutic rigid bronchoscopy allows level of care changes in patients with acute respiratory failure from central airways obstruction. Chest. 1997;112:202\u20136.","journal-title":"Chest"},{"key":"854_CR6","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1183\/09031936.00193409","volume":"36","author":"HC Lin","year":"2010","unstructured":"Lin HC, Chou CL, Chen HC, Chung FT. Airway stent improves outcome in intubated oesophageal cancer patients. Eur Respir J. 2010;36:204\u20135.","journal-title":"Eur Respir J"},{"key":"854_CR7","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1183\/09031936.06.00014006","volume":"28","author":"JM Vergnon","year":"2006","unstructured":"Vergnon JM, Huber RM, Moghissi K. Place of cryotherapy, brachytherapy and photodynamic therapy in therapeutic bronchoscopy of lung cancers. Eur Respir J. 2006;28:200\u201318.","journal-title":"Eur Respir J"},{"key":"854_CR8","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/j.jtcvs.2009.03.051","volume":"139","author":"WS Krimsky","year":"2010","unstructured":"Krimsky WS, Broussard JN, Sarkar SA, et al. Bronchoscopic spray cryotherapy: assessment of safety and depth of airway injury. J Thorac Cardiovasc Surg. 2010;139:781\u20132.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"854_CR9","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1093\/icvts\/ivs192","volume":"15","author":"JT Au","year":"2012","unstructured":"Au JT, Carson J, Monette S, et al. Spray cryotherapy is effective for bronchoscopic, endoscopic and open ablation of thoracic tissues. Interact Cardiovasc Thorac Surg. 2012;15:580\u20134.","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"854_CR10","doi-asserted-by":"publisher","first-page":"2007","DOI":"10.1378\/chest.127.6.2007","volume":"127","author":"G Asimakopoulos","year":"2005","unstructured":"Asimakopoulos G, Beeson J, Evans J, Maiwand MO. Cryosurgery for malignant endobronchial tumors: analysis of outcome. Chest. 2005;127:2007\u201314.","journal-title":"Chest"},{"key":"854_CR11","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1097\/MAJ.0b013e3182367b6a","volume":"344","author":"FT Chung","year":"2012","unstructured":"Chung FT, Chen GY, Chou CL, Chen HC, Yu CT, et al. Airway Ultraflex stenting in Esophago-respiratory fistula caused by esophageal Cancer. Am J Med Sci. 2012;344:105\u20139.","journal-title":"Am J Med Sci"},{"key":"854_CR12","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/1749-8090-6-46","volume":"6","author":"FT Chung","year":"2011","unstructured":"Chung FT, Chen HC, Chou CL, Yu CT, Kuo CH, et al. An outcome analysis of self-expandable metallic stents in central airway obstruction: a cohort study. J Cardiothoracic Surg. 2011;6:46.","journal-title":"J Cardiothoracic Surg"},{"key":"854_CR13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027769","volume":"6","author":"YL Lo","year":"2011","unstructured":"Lo YL, Lin TY, Fang YF, Wang TY, Chen HC, et al. Feasibility of bispectral index-guided propofol infusion for flexible bronchoscopy sedation: a randomized controlled trial. PLoS One. 2011;6:e27769.","journal-title":"PLoS One"},{"key":"854_CR14","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1136\/thx.54.7.581","volume":"54","author":"JC Bestall","year":"1999","unstructured":"Bestall JC, Paul EA, Garrod R, Garnham R, Jones PW, et al. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999;54:581\u20136.","journal-title":"Thorax"},{"key":"854_CR15","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","volume":"5","author":"MM Oken","year":"1982","unstructured":"Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, et al. Toxicity and response criteria of the eastern cooperative oncology group. Am J Clin Oncol. 1982;5:649\u201355.","journal-title":"Am J Clin Oncol"},{"key":"854_CR16","doi-asserted-by":"publisher","first-page":"E1168","DOI":"10.21037\/jtd.2016.10.101","volume":"8","author":"CY Lin","year":"2016","unstructured":"Lin CY, Chung FT. Central airway tumors: interventional bronchoscopy in diagnosis and management. J Thorac Dis. 2016;8:E1168\u201376.","journal-title":"J Thorac Dis"},{"key":"854_CR17","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1378\/chest.06-0975","volume":"131","author":"MM Wahidi","year":"2007","unstructured":"Wahidi MM, Herth FJ, Ernst A. State of the art: interventional pulmonology. Chest. 2007;131:261\u201374.","journal-title":"Chest"},{"key":"854_CR18","doi-asserted-by":"publisher","first-page":"85","DOI":"10.3389\/fonc.2018.00085","volume":"8","author":"J Abdo","year":"2018","unstructured":"Abdo J, Cornell DL, Mittal SK, Agrawal DK, et al. Immunotherapy plus cryotherapy: potential augmented Abscopal effect for advanced cancers. Front Oncol. 2018;8:85.","journal-title":"Front Oncol"},{"key":"854_CR19","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00084-2016","volume":"3","author":"M Bernasconi","year":"2017","unstructured":"Bernasconi M, Koegelenberg CFN, Koutsokera A, et al. Iatrogenic bleeding during flexible bronchoscopy: risk factors, prophylactic measures and management. ERJ Open Res. 2017;3:00084-2016.","journal-title":"ERJ Open Res"}],"container-title":["BMC Pulmonary Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-019-0854-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12890-019-0854-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-019-0854-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T23:07:26Z","timestamp":1590188846000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpulmmed.biomedcentral.com\/articles\/10.1186\/s12890-019-0854-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,24]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["854"],"URL":"https:\/\/doi.org\/10.1186\/s12890-019-0854-2","relation":{},"ISSN":["1471-2466"],"issn-type":[{"value":"1471-2466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,24]]},"assertion":[{"value":"19 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The hospitals\u2019 institutional review board approved the methodology, assurance of patient confidentiality, and project design (IRB No.:100-3211B). All patients or their representatives provided informed consent prior to cryotherapy.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"101"}}