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This study also seeks to determine the prevalence of elevated pulmonary artery systolic pressure in children with PDA.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Patients and methods<\/jats:title>\n                <jats:p>A descriptive study of children with patent ductus arteriosus was carried out from 2016 to 2020 in three institutions. The data were analysed with the IBM SPSS statistics for windows, version 20 (IBM Corp, Chicago)<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Result<\/jats:title>\n                <jats:p>The mean ductal size was 3.78 (2.39) mm, with a minimum of 1.0\u00a0mm and a maximum size of 10.0\u00a0mm. The mean ductal size for males, 4.02 (2.53) mm was comparable with that of the females, 3.61 (2.28) mm (Student T-test\u2009=\u20090.8, 0.4). The mean pulmonary artery systolic pressure (PASP) of the patients was 43.36 (24.46) mmHg. Also the mean PASP was comparable among the males and the females, 48.37 (26.69) mmHg versus 39.63 (22.16) mmHg (Student T-test\u2009=\u20091.81, p\u2009=\u20090.07). There was no correlation between age and PASP (correlation coefficient\u2009=\u20090.009, p\u2009=\u20090.92). Sixty point two percent (60.2%) (62\/103) of children with PDA had pulmonary hypertension. The proportion of males with pulmonary hypertension, 48.39% (30\/62) was comparable with that of the females, 51.61% (32\/62) (Chi<jats:sup>2<\/jats:sup>\u2009=\u20092.05, p\u2009=\u20090.15) and females are 1.8 times more likely to have pulmonary hypertension as males (odds ratio 1.81, 95% CI 0.8\u20134.1). There was a positive correlation between ductal size and PASP (Pearson correlation coefficient\u2009=\u20090.26, p value\u2009=\u20090.007). Those with moderate and large sized duct tend to have moderate and severe pulmonary hypertension respectively and this is statistically significant. Chi<jats:sup>2<\/jats:sup>\u2009=\u200917.85, p\u2009=\u20090.007<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The prevalence of pulmonary hypertension in children with PDA is 60.2%. Moderate and large size duct presents with moderate and severe pulmonary hypertension respectively. Females are 1.8 times more likely to have pulmonary hypertension than the males.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12890-021-01449-y","type":"journal-article","created":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T04:46:43Z","timestamp":1614919603000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["The effects of ductal size on the severity of pulmonary hypertension in children with patent ductus arteriosus (PDA): a multi-center study"],"prefix":"10.1186","volume":"21","author":[{"given":"Josephat M.","family":"Chinawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bartholomew F.","family":"Chukwu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awoere T.","family":"Chinawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chika O.","family":"Duru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,5]]},"reference":[{"key":"1449_CR1","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1016\/j.amjcard.2004.07.082","volume":"94","author":"H Kaemmerer","year":"2004","unstructured":"Kaemmerer H, Meisner H, Hess J, Perloff JK. 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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standard. Ethical approval was obtained from the Ethics and Research committee of the University of Nigeria Teaching hospital Enugu (IRB number of 00002323). Informed written consent was also granted by the parents\/caregivers of subjects, before they were recruited.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"79"}}