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We aimed to clarify the characteristics of radiological and functional lung sequelae of COVID-19 patients described in follow-up period.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Method<\/jats:title>\n                <jats:p>PubMed and EMBASE were searched on January 20th, 2021 to investigate characteristics of lung sequelae in COVID-19 patients. Chest computed tomography (CT) and pulmonary function test (PFT) data were collected and analyzed using one-group meta-analysis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Our search identified 15 eligible studies with follow-up period in a range of 1\u20136\u00a0months. A total of 3066 discharged patients were included in these studies. Among them, 1232 and 1359 patients were evaluated by chest CT and PFT, respectively. The approximate follow-up timing on average was 90\u00a0days after either symptom onset or hospital discharge. The frequency of residual CT abnormalities after hospital discharge was 55.7% (95% confidential interval (CI) 41.2\u201370.1, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200996.2%). The most frequent chest CT abnormality was ground glass opacity in 44.1% (95% CI 30.5\u201357.8, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200996.2%), followed by parenchymal band or fibrous stripe in 33.9% (95% CI 18.4\u201349.4, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200995.0%). The frequency of abnormal pulmonary function test was 44.3% (95% CI 32.2\u201356.4, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200982.1%), and impaired diffusion capacity was the most frequently observed finding in 34.8% (95% CI 25.8\u201343.8, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200991.5%). Restrictive and obstructive patterns were observed in 16.4% (95% CI 8.9\u201323.9, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200989.8%) and 7.7% (95% CI 4.2\u201311.2, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200962.0%), respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This systematic review suggested that about half of the patients with COVID-19 still had residual abnormalities on chest CT and PFT at about 3\u00a0months. Further studies with longer follow-up term are warranted.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12890-021-01463-0","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T12:03:25Z","timestamp":1616414605000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":92,"title":["Radiological and functional lung sequelae of COVID-19: a systematic review and meta-analysis"],"prefix":"10.1186","volume":"21","author":[{"given":"Matsuo","family":"So","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kabata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Fukunaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisato","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiki","family":"Kuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,22]]},"reference":[{"issue":"10224","key":"1463_CR1","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/S0140-6736(20)30251-8","volume":"395","author":"R Lu","year":"2020","unstructured":"Lu R, Zhao X, Li J, et al. 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