{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:18:16Z","timestamp":1772165896551,"version":"3.50.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pulm Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Endobronchial ultrasound-guided transbronchial cryobiopsy (EBUS-cryobiopsy) is advantageous for collecting larger specimens with minimal crushing; however, it has not been widely used for mediastinal tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 73-year-old woman with a history of left breast cancer underwent surgery followed by radiotherapy. Computed tomography showed a mass in the anterior mediastinum that was in extensive contact with the sternum on the ventral side and partly with the trachea on the dorsal side. Two computed tomography-guided needle biopsies (CTNBs) were performed on the mass; however, a definitive diagnosis was not made because of severe crush artifacts. Subsequently, we performed EBUS-cryobiopsy and safely obtained sufficient specimen volume with minimal crushing. The histopathological diagnosis was adenocarcinoma, with immunobiological features distinct from those of previous breast cancers. Her overall diagnosis was a rare tumor originating in the anterior mediastinum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EBUS-cryobiopsy can be safely performed in narrow areas surrounded by major blood vessels, and the obtained specimens may be superior to CTNBs for histopathological diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12890-024-02998-8","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T09:10:20Z","timestamp":1713258620000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adenocarcinoma originating in the anterior mediastinum diagnosed by endobronchial ultrasound-guided transbronchial cryobiopsy: a case report"],"prefix":"10.1186","volume":"24","author":[{"given":"Hiroyuki","family":"Tsuchida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Furuse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaaki","family":"Tsuchida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"2998_CR1","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1136\/thx.48.6.632","volume":"48","author":"B Morrissey","year":"1993","unstructured":"Morrissey B, Adams H, Gibbs AR, Crane MD. Percutaneous needle biopsy of the mediastinum: review of 94 procedures. Thorax. 1993;48:632\u20137. https:\/\/doi.org\/10.1136\/thx.48.6.632.","journal-title":"Thorax"},{"key":"2998_CR2","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1159\/000528644","volume":"102","author":"A Konno-Yamamoto","year":"2023","unstructured":"Konno-Yamamoto A, Matsumoto Y, Imabayashi T, et al. Feasibility of modified endobronchial ultrasound-guided intranodal forceps biopsy: a retrospective analysis. Respiration. 2023;102:143\u201353. https:\/\/doi.org\/10.1159\/000528644.","journal-title":"Respiration"},{"key":"2998_CR3","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1007\/s00330-019-06377-4","volume":"30","author":"HN Lee","year":"2020","unstructured":"Lee HN, Yun SJ, Kim JI, Ryu CW. Diagnostic outcome and safety of CT-guided core needle biopsy for mediastinal masses: a systematic review and meta-analysis. Eur Radiol. 2020;30:588\u201399. https:\/\/doi.org\/10.1007\/s00330-019-06377-4.","journal-title":"Eur Radiol"},{"issue":"10","key":"2998_CR4","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1007\/BF02483955","volume":"28","author":"M Watanabe","year":"1998","unstructured":"Watanabe M, Takagi K, Aoki T, et al. A comparison of biopsy through a parasternal anterior mediastinotomy under local anesthesia and percutaneous needle biopsy for malignant anterior mediastinal tumors. Surg Today. 1998;28(10):1022\u20136. https:\/\/doi.org\/10.1007\/BF02483955.","journal-title":"Surg Today"},{"issue":"1","key":"2998_CR5","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/s0003-4975(01)03182-4","volume":"73","author":"M Metin","year":"2002","unstructured":"Metin M, Sayar A, Turna A, et al. Extended cervical mediastinoscopy in the diagnosis of anterior mediastinal masses. Ann Thorac Surg. 2002;73(1):250\u20132. https:\/\/doi.org\/10.1016\/s0003-4975(01)03182-4.","journal-title":"Ann Thorac Surg"},{"key":"2998_CR6","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/S2213-2600(22)00392-7","volume":"11","author":"Y Fan","year":"2023","unstructured":"Fan Y, Zhang AM, Wu XL, et al. Transbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases: a multicentre, open-label, randomised trial. Lancet Respir Med. 2023;11:256\u201364. https:\/\/doi.org\/10.1016\/S2213-2600(22)00392-7.","journal-title":"Lancet Respir Med"},{"key":"2998_CR7","doi-asserted-by":"publisher","first-page":"2100055","DOI":"10.1183\/13993003.00055-2021","volume":"58","author":"J Zhang","year":"2021","unstructured":"Zhang J, Guo JR, Huang ZS, et al. Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial. Eur Respir J. 2021;58:2100055. https:\/\/doi.org\/10.1183\/13993003.00055-2021.","journal-title":"Eur Respir J"}],"container-title":["BMC Pulmonary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-024-02998-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12890-024-02998-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-024-02998-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T09:10:24Z","timestamp":1713258624000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpulmmed.biomedcentral.com\/articles\/10.1186\/s12890-024-02998-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,16]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2998"],"URL":"https:\/\/doi.org\/10.1186\/s12890-024-02998-8","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3897304\/v1","asserted-by":"object"}]},"ISSN":["1471-2466"],"issn-type":[{"value":"1471-2466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,16]]},"assertion":[{"value":"25 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the National Cancer Center Institutional Review Board (No. 2018-354).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publications"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"181"}}