{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T17:28:31Z","timestamp":1785864511400,"version":"3.56.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pulm Med"],"DOI":"10.1186\/s12890-024-03401-2","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T14:31:26Z","timestamp":1734705086000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A case of pneumonia caused by infection with Tropheryma whipplei complicated by cryptococcus during treatment with a Janus kinase inhibitor: a case report"],"prefix":"10.1186","volume":"24","author":[{"given":"Xiaoxi","family":"Shan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhishu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"issue":"6","key":"3401_CR1","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1080\/17843286.2016.1256586","volume":"71","author":"T Marth","year":"2016","unstructured":"Marth T. Whipple\u2019s disease. Acta Clin Belg. 2016;71(6):373\u20138. https:\/\/doi.org\/10.1080\/17843286.2016.1256586.","journal-title":"Acta Clin Belg"},{"issue":"6","key":"3401_CR2","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1056\/NEJMcps1303787","volume":"373","author":"D Damaraju","year":"2015","unstructured":"Damaraju D, Steiner T, Wade J, Gin K, FitzGerald JM. Clinical problem-solving. A surprising cause of chronic cough. N Engl J Med. 2015;373(6):561\u20136. https:\/\/doi.org\/10.1056\/NEJMcps1303787.","journal-title":"N Engl J Med"},{"issue":"1","key":"3401_CR3","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1515\/med-2021-0297","volume":"16","author":"WM Zhang","year":"2021","unstructured":"Zhang WM, Xu L. Pulmonary parenchymal involvement caused by Tropheryma whipplei. Open Med (Wars). 2021;16(1):843\u20136. https:\/\/doi.org\/10.1515\/med-2021-0297.","journal-title":"Open Med (Wars)"},{"issue":"1","key":"3401_CR4","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12890-020-01384-4","volume":"21","author":"W Li","year":"2021","unstructured":"Li W, Zhang Q, Xu Y, Zhang X, Huang Q, Su Z. Severe pneumonia in adults caused by Tropheryma whipplei and Candida Sp infection: a 2019 case series. BMC Pulm Med. 2021;21(1):29. https:\/\/doi.org\/10.1186\/s12890-020-01384-4.","journal-title":"BMC Pulm Med"},{"key":"3401_CR5","doi-asserted-by":"publisher","first-page":"663093","DOI":"10.3389\/fpubh.2021.663093","volume":"9","author":"J Yan","year":"2021","unstructured":"Yan J, Zhang B, Zhang Z, et al. Case report: Tropheryma whipplei hide in an AIDS patient with pneumocystis pneumonia. Front Public Health. 2021;9:663093. https:\/\/doi.org\/10.3389\/fpubh.2021.663093.","journal-title":"Front Public Health"},{"issue":"10","key":"3401_CR6","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1097\/MEG.0000000000000154","volume":"26","author":"G Sulis","year":"2014","unstructured":"Sulis G, Villanacci V, Missale G, Salemme M, Castelli F, Caligaris S. Whipple\u2019s disease concomitant with candida esophagitis and subsequent Giardia lamblia coinfection. Eur J Gastroenterol Hepatol. 2014;26(10):1181\u20135. https:\/\/doi.org\/10.1097\/MEG.0000000000000154.","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"8","key":"3401_CR7","doi-asserted-by":"publisher","first-page":"4061","DOI":"10.4049\/jimmunol.1101349","volume":"187","author":"K Schinnerling","year":"2011","unstructured":"Schinnerling K, Moos V, Geelhaar A, et al. Regulatory T cells in patients with Whipple\u2019s disease. J Immunol. 2011;187(8):4061\u20137. https:\/\/doi.org\/10.4049\/jimmunol.1101349.","journal-title":"J Immunol"},{"issue":"1","key":"3401_CR8","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1093\/infdis\/jir219","volume":"204","author":"K Al Moussawi","year":"2011","unstructured":"Al Moussawi K, Malou N, Mege JL, Raoult D, Desnues B. An experimental mouse model to establish Tropheryma whipplei as a diarrheal agent. J Infect Dis. 2011;204(1):44\u201350. https:\/\/doi.org\/10.1093\/infdis\/jir219.","journal-title":"J Infect Dis"},{"issue":"3","key":"3401_CR9","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1111\/cmi.12067","volume":"15","author":"SA Johnston","year":"2013","unstructured":"Johnston SA, May RC. Cryptococcus interactions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen. Cell Microbiol. 2013;15(3):403\u201311. https:\/\/doi.org\/10.1111\/cmi.12067.","journal-title":"Cell Microbiol"},{"key":"3401_CR10","doi-asserted-by":"publisher","first-page":"247","DOI":"10.2217\/fmb-2017-0178","volume":"12","author":"JC Lagier","year":"2017","unstructured":"Lagier JC, Fenollar F, Raoult D. Acute infections caused by Tropheryma whipplei. Future Microbiol. 2017;12:247\u201354. https:\/\/doi.org\/10.2217\/fmb-2017-0178.","journal-title":"Future Microbiol"},{"issue":"default","key":"3401_CR11","doi-asserted-by":"publisher","first-page":"129","DOI":"10.2147\/JIR.S35901","volume":"6","author":"M Cutolo","year":"2013","unstructured":"Cutolo M, Meroni M. Clinical utility of the oral JAK inhibitor tofacitinib in the treatment of rheumatoid arthritis. J Inflam Res. 2013;6(default):129\u201337. https:\/\/doi.org\/10.2147\/JIR.S35901.","journal-title":"J Inflam Res"},{"key":"3401_CR12","doi-asserted-by":"publisher","unstructured":"Wang F, Sun L, Wang S et al. Efficacy and safety of tofacitinib, baricitinib, and upadacitinib for rheumatoid arthritis: A systematic review and meta-analysis. Mayo Clin Proc. 2020;95(7):1404\u20131419. https:\/\/doi.org\/10.1016\/j.mayocp.2020.01.039","DOI":"10.1016\/j.mayocp.2020.01.039"},{"issue":"2","key":"3401_CR13","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1053\/j.gastro.2009.10.041","volume":"138","author":"GE Feurle","year":"2010","unstructured":"Feurle GE, Junga NS, Marth T. Efficacy of ceftriaxone or meropenem as initial therapies in Whipple\u2019s disease. Gastroenterology. 2010;138(2):478\u201386. quiz 11, 11\u201312. https:\/\/doi.org\/10.1053\/j.gastro.2009.10.041.","journal-title":"Gastroenterology"},{"issue":"5","key":"3401_CR14","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1093\/mmy\/myy086","volume":"10","author":"Zhejiang Medical Association Society of Respiratory Diseases","year":"2017","unstructured":"Zhejiang Medical Association Society of Respiratory Diseases. Expert consensus on diagnosis and treatment of pulmonary cryptococcosis. Chin J Clin Infect Dis. 2017;10(5):321\u20136. https:\/\/doi.org\/10.1093\/mmy\/myy086.","journal-title":"Chin J Clin Infect Dis"}],"container-title":["BMC Pulmonary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-024-03401-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12890-024-03401-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-024-03401-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T15:02:45Z","timestamp":1734706965000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpulmmed.biomedcentral.com\/articles\/10.1186\/s12890-024-03401-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,20]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3401"],"URL":"https:\/\/doi.org\/10.1186\/s12890-024-03401-2","relation":{},"ISSN":["1471-2466"],"issn-type":[{"value":"1471-2466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,20]]},"assertion":[{"value":"22 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from the individual for the publication of any potentially identifiable images or data included in this article. Clinical trial number: not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors of this manuscript and the patients involved in the article have given their consent for the publication of the paper.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"625"}}