{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:08:22Z","timestamp":1789664902936,"version":"4.0.1"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pulm Med"],"DOI":"10.1186\/s12890-025-04097-8","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:16:28Z","timestamp":1767705388000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Neutrophil-to-lymphocyte ratio for predicting disease severity and outcomes in children with Mycoplasma pneumoniae pneumonia: a systematic review and meta-analysis"],"prefix":"10.1186","volume":"26","author":[{"given":"Ying","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiankun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"issue":"7","key":"4097_CR1","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1093\/cid\/cir531","volume":"53","author":"JS Bradley","year":"2011","unstructured":"Bradley JS, Byington CL, Shah SS, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53(7):e25. https:\/\/doi.org\/10.1093\/cid\/cir531.","journal-title":"Clin Infect Dis"},{"key":"4097_CR2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00329","volume":"7","author":"PM Meyer Sauteur","year":"2016","unstructured":"Meyer Sauteur PM, Unger WW, Nadal D, Berger C, Vink C, van Rossum AM. Infection with and carriage of Mycoplasma pneumoniae in children. Front Microbiol. 2016;7:329. https:\/\/doi.org\/10.3389\/fmicb.2016.00329.","journal-title":"Front Microbiol"},{"issue":"4","key":"4097_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanmic.2024.101019","volume":"6","author":"ESGMAC MAPS study group","year":"2025","unstructured":"ESGMAC MAPS study group. Global spatiotemporal dynamics of Mycoplasma pneumoniae re-emergence after COVID-19 pandemic restrictions: an epidemiological and transmission modelling study. Lancet Microbe. 2025;6(4):101019. https:\/\/doi.org\/10.1016\/j.lanmic.2024.101019.","journal-title":"Lancet Microbe"},{"issue":"1","key":"4097_CR4","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-025-10657-4","volume":"25","author":"F Waldeck","year":"2025","unstructured":"Waldeck F, Kramer TS, Boutin S, Matten J, Kramer J, Rupp J. Re-emergence of Mycoplasma pneumoniae before and after COVID-19 pandemic in Germany. BMC Infect Dis. 2025;25(1):318. https:\/\/doi.org\/10.1186\/s12879-025-10657-4.","journal-title":"BMC Infect Dis"},{"key":"4097_CR5","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2024.1388132","volume":"12","author":"H Du","year":"2024","unstructured":"Du H, Li J, Li X, et al. Impact of the COVID-19 pandemic on epidemiological and clinical characteristics of Mycoplasma pneumoniae pneumonia in children: a multicenter study from Hubei, China. Front Pediatr. 2024;12:1388132. https:\/\/doi.org\/10.3389\/fped.2024.1388132.","journal-title":"Front Pediatr"},{"issue":"1","key":"4097_CR6","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-55311-2","volume":"14","author":"P Li","year":"2024","unstructured":"Li P, Wang W, Zhang X, Pan J, Gong L. Observational retrospective clinical study on clinical features of macrolide-resistant Mycoplasma pneumoniae pneumonia in Chinese pediatric cases. Sci Rep. 2024;14(1):5632. https:\/\/doi.org\/10.1038\/s41598-024-55311-2.","journal-title":"Sci Rep"},{"key":"4097_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2024.101103","volume":"47","author":"KHS Dungu","year":"2024","unstructured":"Dungu KHS, Holm M, Hartling U, et al. Mycoplasma pneumoniae incidence, phenotype, and severity in children and adolescents in Denmark before, during, and after the COVID-19 pandemic: a nationwide multicentre population-based cohort study. Lancet Reg Health Eur. 2024;47:101103. https:\/\/doi.org\/10.1016\/j.lanepe.2024.101103.","journal-title":"Lancet Reg Health Eur"},{"issue":"10","key":"4097_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11102824","volume":"11","author":"L Tong","year":"2022","unstructured":"Tong L, Huang S, Zheng C, Zhang Y, Chen Z. Refractory Mycoplasma pneumoniae pneumonia in children: early recognition and management. J Clin Med. 2022;11(10):2824. https:\/\/doi.org\/10.3390\/jcm11102824.","journal-title":"J Clin Med"},{"issue":"1","key":"4097_CR9","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-024-05279-9","volume":"24","author":"Z Wang","year":"2024","unstructured":"Wang Z, Peng Y, Yang S, et al. Risk factors for complications of Mycoplasma pneumoniae pneumonia in hospitalized children in China: a systematic review and meta-analysis. BMC Pediatr. 2024;24(1):810. https:\/\/doi.org\/10.1186\/s12887-024-05279-9.","journal-title":"BMC Pediatr"},{"issue":"43","key":"4097_CR10","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2025.40.e317","volume":"40","author":"KW Yun","year":"2025","unstructured":"Yun KW. Growing threat of macrolide-resistant Mycoplasma pneumoniae among children: what we know and what we need. J Korean Med Sci. 2025;40(43):e317. https:\/\/doi.org\/10.3346\/jkms.2025.40.e317.","journal-title":"J Korean Med Sci"},{"issue":"10","key":"4097_CR11","doi-asserted-by":"publisher","DOI":"10.3390\/children10101616","volume":"10","author":"AE Domnicu","year":"2023","unstructured":"Domnicu AE, Boia ER, Mogoi M, et al. The neutrophil-to-lymphocyte ratio (NLR) can predict sepsis\u2019s presence and severity in malnourished infants-a single center experience. Children. 2023;10(10):1616. https:\/\/doi.org\/10.3390\/children10101616.","journal-title":"Children"},{"issue":"1","key":"4097_CR12","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-025-01989-7","volume":"51","author":"M Ari","year":"2025","unstructured":"Ari M, Ari HF, Cengiz H. Advanced biomarkers for prognostic evaluation of pneumonia severity in pediatric intensive care: focus on novel inflammatory and hematological ratios. Ital J Pediatr. 2025;51(1):168. https:\/\/doi.org\/10.1186\/s13052-025-01989-7.","journal-title":"Ital J Pediatr"},{"key":"4097_CR13","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268824001134","volume":"152","author":"X Chen","year":"2024","unstructured":"Chen X, Wang S, Cai H, Xia X. The predictive values of C-reactive protein-neutrophil to lymphocyte ratio for the risk of refractory Mycoplasma pneumoniae pneumonia in children: a retrospective cohort study. Epidemiol Infect. 2024;152:e158. https:\/\/doi.org\/10.1017\/S0950268824001134.","journal-title":"Epidemiol Infect"},{"issue":"1","key":"4097_CR14","doi-asserted-by":"publisher","first-page":"114","DOI":"10.21037\/tp-21-568","volume":"11","author":"HH Zheng","year":"2022","unstructured":"Zheng HH, Xiang Y, Wang Y, Zhao QS, Fang R, Dai R. Clinical value of blood related indexes in the diagnosis of bacterial infectious pneumonia in children. Transl Pediatr. 2022;11(1):114\u20139. https:\/\/doi.org\/10.21037\/tp-21-568.","journal-title":"Transl Pediatr"},{"key":"4097_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2025.1552144","volume":"15","author":"L Ding","year":"2025","unstructured":"Ding L, Jiang Y. Biomarkers associated with the diagnosis and prognosis of Mycoplasma pneumoniae pneumonia in children: a review. Front Cell Infect Microbiol. 2025;15:1552144. https:\/\/doi.org\/10.3389\/fcimb.2025.1552144.","journal-title":"Front Cell Infect Microbiol"},{"key":"4097_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cegh.2025.102148","volume":"35","author":"M Lakshmanan","year":"2025","unstructured":"Lakshmanan M, Kumar S, Shashidhara S, et al. Neutrophil-lymphocyte ratio as a point-of-care marker for predicting bacterial etiology in pediatric community-acquired pneumonia: a comparative analysis with C-reactive protein. Clin Epidemiol Glob Health. 2025;35:102148. https:\/\/doi.org\/10.1016\/j.cegh.2025.102148.","journal-title":"Clin Epidemiol Glob Health"},{"key":"4097_CR17","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. https:\/\/doi.org\/10.1136\/bmj.n71.","journal-title":"BMJ"},{"key":"4097_CR18","doi-asserted-by":"publisher","first-page":"6495","DOI":"10.2147\/JIR.S387809","volume":"15","author":"Q Xie","year":"2022","unstructured":"Xie Q, Zhang X, Cui W, Pang Y. Construction of a nomogram for identifying refractory Mycoplasma pneumoniae pneumonia among macrolide-unresponsive Mycoplasma pneumoniae pneumonia in children. J Inflamm Res. 2022;15:6495\u2013504. https:\/\/doi.org\/10.2147\/JIR.S387809.","journal-title":"J Inflamm Res"},{"issue":"1","key":"4097_CR19","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-024-09340-x","volume":"24","author":"S Yang","year":"2024","unstructured":"Yang S, Lu S, Guo Y, Luan W, Liu J, Wang L. A comparative study of general and severe mycoplasma pneumoniae pneumonia in children. BMC Infect Dis. 2024;24(1):449. https:\/\/doi.org\/10.1186\/s12879-024-09340-x.","journal-title":"BMC Infect Dis"},{"issue":"1","key":"4097_CR20","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-025-02137-x","volume":"51","author":"Y Zheng","year":"2025","unstructured":"Zheng Y, Li G, Dai H, Zhu Y. Macrolide-resistant Mycoplasma pneumoniae pneumonia in Chinese children: a retrospective study of clinical features and prognosis. Ital J Pediatr. 2025;51(1):289. https:\/\/doi.org\/10.1186\/s13052-025-02137-x.","journal-title":"Ital J Pediatr"},{"issue":"9","key":"4097_CR21","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1007\/s10654-010-9491-z","volume":"25","author":"A Stang","year":"2010","unstructured":"Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25(9):603\u20135. https:\/\/doi.org\/10.1007\/s10654-010-9491-z.","journal-title":"Eur J Epidemiol"},{"issue":"7414","key":"4097_CR22","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JP Higgins","year":"2003","unstructured":"Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557\u201360. https:\/\/doi.org\/10.1136\/bmj.327.7414.557.","journal-title":"BMJ"},{"issue":"4","key":"4097_CR23","doi-asserted-by":"publisher","first-page":"37","DOI":"10.21608\/ejmm.2018.285639","volume":"27","author":"R El Shabrawy","year":"2018","unstructured":"El Shabrawy R, El Behedy R, Abd-Allatif A, Adel Mohamed E. Neutrophil\/lymphocyte ratio to predict Mycoplasma pneumoniae infection in children with community acquired pneumonia. Egypt J Med Microbiol. 2018;27(4):37\u201343. https:\/\/doi.org\/10.21608\/ejmm.2018.285639.","journal-title":"Egypt J Med Microbiol"},{"issue":"1","key":"4097_CR24","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-025-11132-w","volume":"25","author":"T Ni","year":"2025","unstructured":"Ni T, Zhao F. Predicting myocardial damage in children with mycoplasma pneumoniae pneumonia: a retrospective case-control study. BMC Infect Dis. 2025;25(1):733. https:\/\/doi.org\/10.1186\/s12879-025-11132-w.","journal-title":"BMC Infect Dis"},{"issue":"1","key":"4097_CR25","doi-asserted-by":"publisher","DOI":"10.1186\/s12938-025-01410-8","volume":"24","author":"S Mu","year":"2025","unstructured":"Mu S, Zhai J, Guo Y, Huang B, Zou Y. Prediction of risk factors of plastic bronchitis in children with severe Mycoplasma pneumoniae pneumonia. Biomed Eng Online. 2025;24(1):75. https:\/\/doi.org\/10.1186\/s12938-025-01410-8.","journal-title":"Biomed Eng Online"},{"issue":"1","key":"4097_CR26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-58784-3","volume":"14","author":"X Zhang","year":"2024","unstructured":"Zhang X, Sun R, Jia W, Li P, Song C. A new dynamic nomogram for predicting the risk of severe Mycoplasma pneumoniae pneumonia in children. Sci Rep. 2024;14(1):8260. https:\/\/doi.org\/10.1038\/s41598-024-58784-3.","journal-title":"Sci Rep"},{"issue":"34","key":"4097_CR27","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000039375","volume":"103","author":"H Pei","year":"2024","unstructured":"Pei H, Luo H. Predictive clinical indicators of refractory Mycoplasma pneumoniae pneumonia in children: a retrospective cohort study. Medicine (Baltimore). 2024;103(34):e39375. https:\/\/doi.org\/10.1097\/MD.0000000000039375.","journal-title":"Medicine (Baltimore)"},{"key":"4097_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2024.1489389","volume":"12","author":"Y Li","year":"2024","unstructured":"Li Y, Liu Y, Chen X, et al. Clinical characteristics and predictive indictors of macrolide-unresponsive Mycoplasma pneumoniae pneumonia in children: a retrospective study. Front Pediatr. 2024;12:1489389. https:\/\/doi.org\/10.3389\/fped.2024.1489389.","journal-title":"Front Pediatr"},{"issue":"1","key":"4097_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-020-01577-9","volume":"22","author":"J Wen","year":"2021","unstructured":"Wen J, Su Y, Sun H, Zhang H, Li H. The combination of initial markers to predict refractory Mycoplasma pneumoniae pneumonia in Chinese children: a case control study. Respir Res. 2021;22(1):89. https:\/\/doi.org\/10.1186\/s12931-020-01577-9.","journal-title":"Respir Res"},{"key":"4097_CR30","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.659677","volume":"9","author":"Y Ling","year":"2021","unstructured":"Ling Y, Ning J, Xu Y. Explore the predictive value of peripheral blood cell parameters in refractory Mycoplasma pneumoniae pneumonia in children over 6 years old. Front Pediatr. 2021;9:659677. https:\/\/doi.org\/10.3389\/fped.2021.659677.","journal-title":"Front Pediatr"},{"key":"4097_CR31","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1302702","volume":"14","author":"D Li","year":"2023","unstructured":"Li D, Gu H, Chen L, et al. Neutrophil-to-lymphocyte ratio as a predictor of poor outcomes of Mycoplasma pneumoniae pneumonia. Front Immunol. 2023;14:1302702. https:\/\/doi.org\/10.3389\/fimmu.2023.1302702.","journal-title":"Front Immunol"},{"issue":"3","key":"4097_CR32","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.25150","volume":"39","author":"L Shao","year":"2025","unstructured":"Shao L, Yu B, Lyu Y, Fan S, Gu C, Wang H. The clinical value of novel inflammatory biomarkers for predicting Mycoplasma pneumoniae infection in children. J Clin Lab Anal. 2025;39(3):e25150. https:\/\/doi.org\/10.1002\/jcla.25150.","journal-title":"J Clin Lab Anal"},{"issue":"1","key":"4097_CR33","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3969\/j.issn.1002-0217","volume":"42","author":"B Bing","year":"2023","unstructured":"Bing B, Yajin L, Yan C, et al. Value of NLR, SII and D-dimer in evaluating poor prognosis in children with Mycoplasma pneumoniae pneumonia. J Wannan Med Coll. 2023;42(1):21\u20134. https:\/\/doi.org\/10.3969\/j.issn.1002-0217.","journal-title":"J Wannan Med Coll"},{"issue":"7","key":"4097_CR34","doi-asserted-by":"publisher","first-page":"813","DOI":"10.3969\/j.issn.1000-0399","volume":"41","author":"L Xueqin","year":"2020","unstructured":"Xueqin L, Yingxin F. Correlation between NLR and PLR and disease severity in children with Mycoplasma pneumoniae pneumonia and its predictive value for prognosis. Anhui Med J. 2020;41(7):813\u20135. https:\/\/doi.org\/10.3969\/j.issn.1000-0399.","journal-title":"Anhui Med J"},{"issue":"1","key":"4097_CR35","doi-asserted-by":"publisher","first-page":"73","DOI":"10.3969\/j.issn.1009-5519","volume":"40","author":"W Lijuan","year":"2024","unstructured":"Lijuan W, Jun D, Ziwei Z, et al. Diagnostic and prognostic value of NLR and PLR detection in children with Mycoplasma pneumonia infection. J Mod Med Health. 2024;40(1):73\u20136. https:\/\/doi.org\/10.3969\/j.issn.1009-5519.","journal-title":"J Mod Med Health"},{"issue":"3","key":"4097_CR36","doi-asserted-by":"publisher","first-page":"128","DOI":"10.3969\/j.issn.1672-0369","volume":"36","author":"N Chunhong","year":"2024","unstructured":"Chunhong N, Haiyang Y. Predictive value of combined detection of AA\/hs-CRP, NLR and PCT levels in diagnosing children with Mycoplasma pneumoniae pneumonia. Med J Chin Peoples Health. 2024;36(3):128\u201331. https:\/\/doi.org\/10.3969\/j.issn.1672-0369.","journal-title":"Med J Chin Peoples Health"},{"issue":"11","key":"4097_CR37","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.3969\/j.issn.1002-7386","volume":"46","author":"H Kaiyin","year":"2024","unstructured":"Kaiyin H, Le L, Ting Z, et al. Correlation of SAA, CRP, NLR and PLR with disease progression and humoral immunity in children infected with Mycoplasma pneumoniae. Hebei Med J. 2024;46(11):1656\u201360. https:\/\/doi.org\/10.3969\/j.issn.1002-7386.","journal-title":"Hebei Med J"},{"issue":"6","key":"4097_CR38","doi-asserted-by":"publisher","first-page":"568","DOI":"10.3969\/j.issn.1673-8640","volume":"39","author":"D Yao","year":"2024","unstructured":"Yao D, Jiahui L, Xiuhong X, et al. Prognosis evaluation model of children with Mycoplasma pneumoniae pneumonia based on MP DNA and peripheral blood inflammation indicators. Lab Med. 2024;39(6):568\u201372. https:\/\/doi.org\/10.3969\/j.issn.1673-8640.","journal-title":"Lab Med"},{"issue":"11","key":"4097_CR39","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.3969\/j.issn.1672-9455","volume":"21","author":"W Juan","year":"2024","unstructured":"Juan W, Cuiping S. The predictive value of NLR, PLR, and MPVLR combined with CRP in peripheral blood in children with refractory Mycoplasma pneumoniae pneumonia. Lab Med Clin. 2024;21(11):1631\u20135. https:\/\/doi.org\/10.3969\/j.issn.1672-9455.","journal-title":"Lab Med Clin"},{"issue":"18","key":"4097_CR40","doi-asserted-by":"publisher","first-page":"29","DOI":"10.19368\/j.cnki.2096-1782","volume":"7","author":"W Tao","year":"2022","unstructured":"Tao W, liner Y, Yitao C, et al. Clinical significance of neutrophil to lymphocyte ratio and monocyte to lymphocyte ratio in children with Mycoplasma pneumonia. Syst Med. 2022;7(18):29\u201332. https:\/\/doi.org\/10.19368\/j.cnki.2096-1782.","journal-title":"Syst Med"},{"issue":"8","key":"4097_CR41","doi-asserted-by":"publisher","first-page":"973","DOI":"10.3969\/j.issn.1000-7377","volume":"50","author":"Z Yan","year":"2021","unstructured":"Yan Z. Changes and significance of serum NLR and PLR level in children with Mycoplasma pneumoniae infection. Shaanxi Med J. 2021;50(8):973\u20136. https:\/\/doi.org\/10.3969\/j.issn.1000-7377.","journal-title":"Shaanxi Med J"},{"issue":"4","key":"4097_CR42","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3760\/cma.j.cn101070-20201013-01612","volume":"37","author":"Z Furong","year":"2022","unstructured":"Furong Z, Weifang Z, Yuqin L, et al. The diagnostic value of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in severe Mycoplasma pneumoniae pneumonia. Chin J Pract Clin Pediatr. 2022;37(4):5. https:\/\/doi.org\/10.3760\/cma.j.cn101070-20201013-01612.","journal-title":"Chin J Pract Clin Pediatr"},{"issue":"1","key":"4097_CR43","doi-asserted-by":"publisher","first-page":"102","DOI":"10.3969\/j.issn.2097-115X","volume":"4","author":"S Zhihai","year":"2025","unstructured":"Zhihai S. Value of neutrophil-to-lymphocyte ratio, procalcitonin, and neutrophil CD64 index in evaluating the severity of Mycoplasma pneumoniae pneumonia. Matern Child Health Rev. 2025;4(1):102\u20136. https:\/\/doi.org\/10.3969\/j.issn.2097-115X.","journal-title":"Matern Child Health Rev"},{"issue":"12","key":"4097_CR44","doi-asserted-by":"publisher","first-page":"2042","DOI":"10.13241\/j.cnki.pmb.2025.12.017","volume":"25","author":"L Zhenchang","year":"2025","unstructured":"Zhenchang L, Yuanfang L, Juan L, et al. Evaluation value of blood routine\u2013derived parameters combined with serum CRP and PCT in predicting clinical outcomes of children with Mycoplasma pneumoniae pneumonia. Progress Mod Biomed. 2025;25(12):2042\u201320472063. https:\/\/doi.org\/10.13241\/j.cnki.pmb.2025.12.017.","journal-title":"Progress Mod Biomed"},{"issue":"20","key":"4097_CR45","doi-asserted-by":"publisher","first-page":"11","DOI":"10.14033\/j.cnki.cfmr.2025.20.004","volume":"23","author":"C Peican","year":"2025","unstructured":"Peican C, Zhenjie Z, Jiawei L. Relationship of PLR, NLR, and MLR with disease severity in children with Mycoplasma pneumoniae pneumonia. Chin Foreign Med Res. 2025;23(20):11\u20134. https:\/\/doi.org\/10.14033\/j.cnki.cfmr.2025.20.004.","journal-title":"Chin Foreign Med Res"},{"issue":"12","key":"4097_CR46","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.3969\/j.issn.1004-5775","volume":"49","author":"H Jing","year":"2025","unstructured":"Jing H, Shunan L. Predictive value of combined CRP\/PCT, LDH, and NLR testing in children with refractory Mycoplasma pneumoniae pneumonia. Heilongjiang Med J. 2025;49(12):1469\u201371. https:\/\/doi.org\/10.3969\/j.issn.1004-5775.","journal-title":"Heilongjiang Med J"},{"issue":"1","key":"4097_CR47","doi-asserted-by":"publisher","first-page":"82","DOI":"10.14033\/j.cnki.cfmr.2024.01.021","volume":"22","author":"M Rong","year":"2024","unstructured":"Rong M, Guojin Y, Jing P. Clinical value of peripheral blood eosinophils combined with neutrophil-to-lymphocyte ratio in diagnosing Mycoplasma pneumoniae infection in children. Zhongwai Med Res. 2024;22(1):82\u20135. https:\/\/doi.org\/10.14033\/j.cnki.cfmr.2024.01.021.","journal-title":"Zhongwai Med Res"},{"issue":"2","key":"4097_CR48","doi-asserted-by":"publisher","first-page":"410","DOI":"10.14035\/j.cnki.hljyy.2025.02.056","volume":"38","author":"C Juan","year":"2025","unstructured":"Juan C. Diagnostic value of SAA, NLR combined with serum PCT in children with Mycoplasma pneumoniae pneumonia. Heilongjiang Med J. 2025;38(2):410\u20132. https:\/\/doi.org\/10.14035\/j.cnki.hljyy.2025.02.056.","journal-title":"Heilongjiang Med J"},{"key":"4097_CR49","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.824027","volume":"12","author":"M Chen","year":"2022","unstructured":"Chen M, Deng H, Zhao Y, et al. Toll-like receptor 2 modulates pulmonary inflammation and TNF-\u03b1 release mediated by Mycoplasma pneumoniae. Front Cell Infect Microbiol. 2022;12:824027. https:\/\/doi.org\/10.3389\/fcimb.2022.824027.","journal-title":"Front Cell Infect Microbiol"},{"issue":"11","key":"4097_CR50","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1012614","volume":"20","author":"C Wang","year":"2024","unstructured":"Wang C, Wen J, Yan Z, et al. Suppressing neutrophil itaconate production attenuates Mycoplasma pneumoniae pneumonia. PLoS Pathog. 2024;20(11):e1012614. https:\/\/doi.org\/10.1371\/journal.ppat.1012614.","journal-title":"PLoS Pathog"},{"issue":"9","key":"4097_CR51","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.21037\/tp-24-172","volume":"13","author":"C Jiang","year":"2024","unstructured":"Jiang C, Bao S, Shen W, Wang C. Predictive value of immune-related parameters in severe Mycoplasma pneumoniae pneumonia in children. Transl Pediatr. 2024;13(9):1521\u20138. https:\/\/doi.org\/10.21037\/tp-24-172.","journal-title":"Transl Pediatr"},{"issue":"1","key":"4097_CR52","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-023-04456-6","volume":"23","author":"M Xu","year":"2023","unstructured":"Xu M, Zhou L, Zhang J, Luo S, Zhao Y, Xiong W. Neutrophil to lymphocyte ratio in pediatric patients with asthmatic exacerbation and community-acquired pneumonia. BMC Pediatr. 2023;23(1):640. https:\/\/doi.org\/10.1186\/s12887-023-04456-6.","journal-title":"BMC Pediatr"},{"issue":"21","key":"4097_CR53","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e38950","volume":"10","author":"L Fan","year":"2024","unstructured":"Fan L, Xu N, Guo Y, Li L. Enhanced insights into the neutrophil-driven immune mechanisms during Mycoplasma pneumoniae infection. Heliyon. 2024;10(21):e38950. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e38950.","journal-title":"Heliyon"},{"key":"4097_CR54","doi-asserted-by":"publisher","unstructured":"Wang Y, Wang M, Sun J. The predictive value of D-dimer and neutrophil-to-lymphocyte ratio for the severity of severe pneumonia in children. Postgrad Med https:\/\/doi.org\/10.1080\/00325481.2025.2587365","DOI":"10.1080\/00325481.2025.2587365"}],"container-title":["BMC Pulmonary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12890-025-04097-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-025-04097-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12890-025-04097-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T13:56:19Z","timestamp":1770126979000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12890-025-04097-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,6]]},"references-count":54,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4097"],"URL":"https:\/\/doi.org\/10.1186\/s12890-025-04097-8","relation":{},"ISSN":["1471-2466"],"issn-type":[{"value":"1471-2466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,6]]},"assertion":[{"value":"13 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"50"}}