{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T12:42:16Z","timestamp":1754397736772,"version":"3.37.3"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T00:00:00Z","timestamp":1572307200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T00:00:00Z","timestamp":1572307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Musculoskelet Disord"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n              <jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Recently, various studies have reported the importance of distinguishing between balanced and unbalanced SL, sustaining the importance of SL reduction in unbalanced cases. In this study we present our experience in the treatment of isthmic spondylolisthesis in young patients, observing the correlation between SL reduction and sagittal correlation between spine and pelvis.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This is a retrospective study of a series of patients treated surgically for isthmic spondylolisthesis. Inclusion criteria were L5-S1 isthmic spondylolisthesis of III\u00b0 or IV\u00b0, pediatric age, clinical and radiographic follow up of at least 1\u2009year. Radiographic evaluation included the following elements: grade and percentage of listhesis (%L), lumbar lordosis (LL), lumbar-sacral angle (LSA), pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT) distinguishing between \u201cbalanced\u201d and \u201cunbalanced\u201d patients. Radiographic values were confronted by using Student\u2019s t- test, obtaining a statistically significant difference for values inferior to 0,05.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Based on inclusion criteria, 28 patients were selected for our retrospective analysis, 19 female and 9 male. Mean age at surgery was 15,6\u2009years. Mean follow up was 3\u2009years and 3\u2009months (min. 1\u2009year \u2013 max 6\u2009years and 7\u2009months). Spondylolisthesis reduction was statistically significant both in balanced and in unbalanced patients, but pelvic incidence values did not improve significantly. We observed fewer mechanical complications in patients treated with interbody support.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In our study, differences between pre-op and post-op spinopelvic alignment values were not statistically significant, even though spondylolisthesis reduction was statistically significant in all cases. Our study could be considered an initial attempt to correlate spinopelvic changes to spondylolisthesis reduction in a progressive manner, and possibly in the future, generate threshold values of reduction for ideal spinopelvic alignment in every different patient.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12891-019-2865-9","type":"journal-article","created":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T20:44:43Z","timestamp":1572468283000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["High grade isthmic spondylolisthesis; can reduction always re-align the unbalanced pelvis?"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1923-6163","authenticated-orcid":false,"given":"Konstantinos","family":"Martikos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiziana","family":"Greggi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Faldini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,10,29]]},"reference":[{"issue":"20","key":"2865_CR1","doi-asserted-by":"publisher","first-page":"2208","DOI":"10.1097\/BRS.0b013e31814b2cee","volume":"32","author":"MT Hresko","year":"2007","unstructured":"Hresko MT, Labelle H, Roussouly P, Berthonnaud E. Classification of high grade spondylolisthesis based on pelvic version and spine balance: possible rationale for reduction. Spine (Phila Pa 1976). 2007;32(20):2208\u201313.","journal-title":"Spine (Phila Pa 1976)"},{"issue":"18","key":"2865_CR2","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1097\/01.brs.0000138279.53439.cc","volume":"29","author":"H Labelle","year":"2004","unstructured":"Labelle H, Roussouly P, Berthonnaud E, et al. Spondylolisthesis, pelvic incidence and spinopelvic balance: a correlation study. Spine (Phila Pa 1976). 2004;29(18):2049\u201354.","journal-title":"Spine (Phila Pa 1976)"},{"key":"2865_CR3","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.1097\/00007632-200209150-00010","volume":"27","author":"L Curylo","year":"2002","unstructured":"Curylo L, Edwards C, DeWald RW. Radographic marlers in spondyloptosis: implications for spondylolisthesis progression. Spine (Phila Pa 1976). 2002;27:2021\u20135.","journal-title":"Spine (Phila Pa 1976)"},{"key":"2865_CR4","doi-asserted-by":"publisher","first-page":"2026","DOI":"10.1097\/00007632-200209150-00011","volume":"27","author":"DS Hanson","year":"2002","unstructured":"Hanson DS, Bridwell KH, Rhee J, et al. Correlation of pelvic incidence with low and high grade isthmic spondylolisthesis. Spine. 2002;27:2026\u20139.","journal-title":"Spine"},{"key":"2865_CR5","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.1097\/01.BRS.0000132312.78469.7B","volume":"29","author":"JM Mac-Thiong","year":"2004","unstructured":"Mac-Thiong JM, Labelle H, Berthonnaud E, et al. Sagittal alignment of the spine and pelvis during growth. Spine. 2004;29:1642\u20137.","journal-title":"Spine"},{"issue":"21","key":"2865_CR6","doi-asserted-by":"publisher","first-page":"2316","DOI":"10.1097\/BRS.0b013e318186b236","volume":"33","author":"JM Mac-Thing","year":"2008","unstructured":"Mac-Thing JM, Wang Z, de Guise JA, Labelle H. Postural model of sagittal spino-pelvic alignment and its relevance for lumbosacral developmental spondylolisthesis. Spine (Phila Pa 1976). 2008;33(21):2316\u201325.","journal-title":"Spine (Phila Pa 1976)"},{"key":"2865_CR7","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1007\/s00586-008-0713-y","volume":"17","author":"H Labelle","year":"2008","unstructured":"Labelle H, Roussouly P, Chopin D, Berthonnaud E, Hresko T. Spino-pelvic alignment after surgical correction for developmental spondylolisthesis. Eur Spine J. 2008;17:1170\u20136.","journal-title":"Eur Spine J"},{"issue":"2","key":"2865_CR8","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1097\/BPO.0b013e3181977de8","volume":"29","author":"MT Hresko","year":"2009","unstructured":"Hresko MT, Hirschfeld R, Buerk AA, Zurakowski D. The effect of reduction and instrumentation of spondylolisthesis on spinopelvic sagittal alignment. J Pediatr Orthop. 2009 Mar;29(2):157\u201362.","journal-title":"J Pediatr Orthop"}],"container-title":["BMC Musculoskeletal Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12891-019-2865-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12891-019-2865-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12891-019-2865-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:11:12Z","timestamp":1603843872000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-019-2865-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,29]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["2865"],"URL":"https:\/\/doi.org\/10.1186\/s12891-019-2865-9","relation":{},"ISSN":["1471-2474"],"issn-type":[{"type":"electronic","value":"1471-2474"}],"subject":[],"published":{"date-parts":[[2019,10,29]]},"assertion":[{"value":"9 January 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 October 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The Rizzoli Orthopaedic Institute Ethics Comitee was consulted prior to undertaking this study. Written informed consent for participating in this study was obtained from all patients and patient\u2019s parents.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"This manuscript has the consent of the patient and patient\u2019s parent for the use of her data. The authors obtained the written consent of the patient and patient\u2019s parent for the publication of the data and images that appear in the article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"499"}}