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Outcomes at 1\u00a0year after ATR consisted of the patient-reported Achilles tendon Total Rupture Score (ATRS) and the functional heel-rise tests reported as the limb symmetry index (LSI). The non-inferiority statistical 10% margin was calculated as a reflection of a clinically acceptable disadvantage in ATRS and heel-rise outcome when comparing treatments.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 422 patients (350 males and 72 females) aged between 18 and 71\u2009years, with a mean age of 40.6 (standard deviation 8.6), were included. A total of 363 (86%) patients were treated surgically. The ATRS (difference (\u0394)\u2009=\u2009\u2212\u20090.253 [95% confidence interval (CI); \u2212\u20095.673;5.785] <jats:italic>p<\/jats:italic>\u2009=\u20090.36) and LSI of heel-rise height (difference\u2009=\u20091.43 [95% CI; \u2212\u20092.43;5.59] <jats:italic>p<\/jats:italic>\u2009=\u20090.81), total work (difference\u2009=\u20090.686 [95% CI; \u2212\u20094.520;6.253] <jats:italic>p<\/jats:italic>\u2009=\u20090.67), concentric power (difference\u2009=\u20092.93 [95% CI; \u2212\u20096.38;11.90] <jats:italic>p<\/jats:italic>\u2009=\u20090.063) and repetitions (difference\u2009=\u2009\u2212\u20091.30 [95% CI; \u2212\u20096.32;4.13] <jats:italic>p<\/jats:italic>\u2009=\u20090.24) resulted in non-inferiority within a \u0394 \u2212\u200910% margin for patients treated non-surgically.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The non-surgical treatment of Achilles tendon ruptures is not inferior compared with that of surgery in terms of 1-year patient-reported and functional outcomes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12891-020-03320-3","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T16:06:12Z","timestamp":1591632372000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Treatment of acute Achilles tendon rupture \u2013 a multicentre, non-inferiority analysis"],"prefix":"10.1186","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8416-8905","authenticated-orcid":false,"given":"Olof","family":"Westin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Sj\u00f6gren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Svedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Horvath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Hamrin Senorski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Samuelsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Ackermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"issue":"4","key":"3320_CR1","doi-asserted-by":"publisher","first-page":"380","DOI":"10.5312\/wjo.v6.i4.380","volume":"6","author":"V Gulati","year":"2015","unstructured":"Gulati V, Jaggard M, Al-Nammari SS, Uzoigwe C, Gulati P, Ismail N, et al. 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The original datasets of the included randomised control trials can be accessed by contacting the corresponding author.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"358"}}