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The purpose of this study was to develop three-dimensional printed patient-specific (3DPPS) Ti-6Al-4\u2009V plates to treat complicated acetabular fractures involving quadrilateral plate (QLP) disruption and to evaluate their efficacy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty patients with acetabular fractures involving QLP disruption were selected between January 2016 and June 2017. Patients were divided into a control group (Group A, 35 patients) and an experimental group (Group B, 15 patients), and were treated by the conventional method of shaping reconstruction plates or with 3DPPS Ti-6AL-4\u2009V plates, respectively. The efficacy of Ti-6AL-4\u2009V plates was evaluated by blood loss, operative time, reduction quality, postoperative residual displacement, and complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The operative time and blood loss in Group B were reduced compared to Group A, and the difference was statistically significant (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). There was no significant difference in reduction quality between the two groups (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). Reduction quality in Group B was anatomic in 10 (66.7%), satisfactory in four (26.7%), and poor in one (6.7%). In Group A, they were anatomic in 18 (51.4%), satisfactory in 13 (37.1%), and poor in four (11.4%). Residual displacement in Group B was less than that in Group A, and the difference was statistically significant (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). In Group B, one case exhibited loosening of the pubic screw postoperatively. In Group A, there was one case of wound infection, one of deep vein thrombosis (DVT) in the ipsilateral lower limb, one case of traumatic arthritis and two obturator nerve injuries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The 3DPPS Ti-6AL-4\u2009V plate is a feasible, accurate and effective implant for acetabular fracture treatment.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12891-020-03370-7","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T11:03:05Z","timestamp":1594378985000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Three-dimensional printing of patient-specific plates for the treatment of acetabular fractures involving quadrilateral plate disruption"],"prefix":"10.1186","volume":"21","author":[{"given":"Canbin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuezhi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyuan","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuancheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuming","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lufeng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shicai","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhua","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3961-1688","authenticated-orcid":false,"given":"Jianghui","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,10]]},"reference":[{"key":"3370_CR1","first-page":"139","volume":"64","author":"BR Moed","year":"2015","unstructured":"Moed BR, Kregor PJ, Reilly MC, Stover MD, Vrahas MS. 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All procedures performed involving human participants were in accordance with the ethical standards of the institutional and\/or National Research Committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Written informed consent was obtained from all patients. The 3DPPS plates have already been approved\u2002and certificated\u2002by\u2002CFDA (The Class\u2002III\u2002medical\u2002device, NO. 20163460576). In addition, this study has been registered in Chinese Clinical Trial Registry (ChiCTR, NO: hiCTR1800017149).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"451"}}