{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T21:13:01Z","timestamp":1794604381732,"version":"4.9.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T00:00:00Z","timestamp":1618185600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T00:00:00Z","timestamp":1618185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81560374"],"award-info":[{"award-number":["81560374"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81960399"],"award-info":[{"award-number":["81960399"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004763","name":"Natural Science Foundation of Inner Mongolia","doi-asserted-by":"publisher","award":["2018BS08002"],"award-info":[{"award-number":["2018BS08002"]}],"id":[{"id":"10.13039\/501100004763","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004763","name":"Natural Science Foundation of Inner Mongolia","doi-asserted-by":"publisher","award":["2020MS03064"],"award-info":[{"award-number":["2020MS03064"]}],"id":[{"id":"10.13039\/501100004763","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Musculoskelet Disord"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Gout is a metabolic disease characterized by recurrent episodes of acute arthritis. Gout has been reported in many locations but is rarely localized in the shoulder joint. We describe a rare case of gouty arthritis involving bilateral shoulder joints and leading to severe destructive changes in the right shoulder glenoid.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 62-year-old male was referred for pain and weakness in the right shoulder joint for two years, and the pain had increased in severity over the course of approximately nine months. A clinical examination revealed gout nodules on both feet and elbows. A laboratory examination showed a high erythrocyte sedimentation rate (ESR), high levels of C-reactive protein and hyperuricemia, and an imaging examination showed severe osteolytic destruction of the right shoulder glenoid and posterior humeral head subluxation. In addition, the left humeral head was involved and had a lytic lesion. Because a definite diagnosis could not be made for this patient, a right shoulder biopsy was performed. The pathological examination of the specimen revealed uric acid crystal deposits and granulomatous inflammation surrounding the deposits. After excluding infectious and neoplastic diseases, the patient was finally diagnosed with gouty shoulder arthritis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Gout affecting the bilateral shoulder joints is exceedingly uncommon, and to our knowledge, severe erosion of the glenoid has not been previously reported. When severe erosion is present, physicians and orthopedic surgeons should consider gouty shoulder arthritis according to previous medical history and clinical manifestations.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12891-021-04217-5","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T14:03:19Z","timestamp":1618236199000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Severe erosive lesion of the glenoid in gouty shoulder arthritis: a case report and review of the literature"],"prefix":"10.1186","volume":"22","author":[{"given":"Huricha","family":"Bao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yansong","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baogang","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingxian","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongsheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,12]]},"reference":[{"issue":"1","key":"4217_CR1","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/s12891-018-2044-4","volume":"19","author":"S Alqatari","year":"2018","unstructured":"Alqatari S, Visevic R, Marshall N, Ryan J, Murphy G. An unexpected cause of sacroiliitis in a patient with gout and chronic psoriasis with inflammatory arthritis: a case report. BMC Musculoskelet Disord. 2018;19(1):126.","journal-title":"BMC Musculoskelet Disord"},{"issue":"Suppl 3","key":"4217_CR2","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.semarthrit.2020.04.008","volume":"50","author":"JA Singh","year":"2020","unstructured":"Singh JA, Gaffo A. Gout epidemiology and comorbidities. Semin Arthritis Rheum. 2020;50(Suppl 3):11\u20136.","journal-title":"Semin Arthritis Rheum"},{"issue":"7","key":"4217_CR3","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1038\/s41584-020-0441-1","volume":"16","author":"M Dehlin","year":"2020","unstructured":"Dehlin M, Jacobsson L, Roddy E. Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors. Nat Rev Rheumatol. 2020;16(7):380\u201390.","journal-title":"Nat Rev Rheumatol"},{"issue":"2","key":"4217_CR4","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1067\/mse.2003.24","volume":"12","author":"ST O\u2019leary","year":"2003","unstructured":"O\u2019leary ST, Goldberg JA, Walsh WR. Tophaceous gout of the rotator cuff: a case report. J Shoulder Elbow Surg. 2003;12(2):200\u20131.","journal-title":"J Shoulder Elbow Surg"},{"issue":"1","key":"4217_CR5","doi-asserted-by":"publisher","first-page":"178","DOI":"10.2106\/JBJS.G.00249","volume":"90","author":"CH Chang","year":"2008","unstructured":"Chang CH, Lu CH, Yu CW, Wu MZ, Hsu CY, Shih TT. Tophaceous gout of the rotator cuff. A case report. J Bone Joint Surg Am. 2008;90(1):178\u201382.","journal-title":"J Bone Joint Surg Am"},{"issue":"3","key":"4217_CR6","first-page":"4718","volume":"8","author":"T Ichiseki","year":"2015","unstructured":"Ichiseki T, Ueda S, Matsumoto T. Rare coexistence of gouty and septic arthritis after arthroscopic rotator cuff repair: a case report. Int J Clin Exp Med. 2015;8(3):4718\u201320.","journal-title":"Int J Clin Exp Med"},{"issue":"5","key":"4217_CR7","doi-asserted-by":"publisher","first-page":"e55-6","DOI":"10.1016\/j.reuma.2017.05.011","volume":"15","author":"AM Tierra Rodriguez","year":"2019","unstructured":"Tierra Rodriguez AM, Pantoja Zarza L, Bra\u00f1anova L\u00f3pez P, Diez Morrondo C. Tophaceous gout of the shoulder joint. Reumatol Clin. 2019;15(5):e55-6.","journal-title":"Reumatol Clin"},{"issue":"5","key":"4217_CR8","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.jare.2017.04.008","volume":"8","author":"G Ragab","year":"2017","unstructured":"Ragab G, Elshahaly M, Bardin T. Gout: An old disease in new perspective - A review. J Adv Res. 2017;8(5):495\u2013511.","journal-title":"J Adv Res"},{"issue":"3","key":"4217_CR9","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1007\/s11926-996-0030-6","volume":"8","author":"A Gentili","year":"2006","unstructured":"Gentili A. The advanced imaging of gouty tophi. Curr Rheumatol Rep. 2006;8(3):231\u20135.","journal-title":"Curr Rheumatol Rep"},{"issue":"6","key":"4217_CR10","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1186\/ar3489","volume":"13","author":"FM McQueen","year":"2011","unstructured":"McQueen FM, Doyle A, Dalbeth N. Imaging in gout\u2013what can we learn from MRI, CT, DECT and US. Arthritis Res Ther. 2011;13(6):246.","journal-title":"Arthritis Res Ther"},{"issue":"4","key":"4217_CR11","doi-asserted-by":"publisher","first-page":"e19","DOI":"10.1016\/j.jse.2011.01.034","volume":"20","author":"UG Longo","year":"2011","unstructured":"Longo UG, Marinozzi A, Cazzato L, Rabitti C, Maffulli N, Denaro V. Tuberculosis of the shoulder. J Shoulder Elbow Surg. 2011;20(4):e19\u201321.","journal-title":"J Shoulder Elbow Surg"},{"issue":"6","key":"4217_CR12","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1016\/j.jse.2014.10.020","volume":"24","author":"AL Kekatpure","year":"2015","unstructured":"Kekatpure AL, Sun JH, Sim GB, Chun JM, Jeon IH. Rapidly destructive arthrosis of the shoulder joints: radiographic, magnetic resonance imaging, and histopathologic findings. J Shoulder Elbow Surg. 2015;24(6):922\u20137.","journal-title":"J Shoulder Elbow Surg"},{"key":"4217_CR13","unstructured":"Nadarajah CV, Weichert I. Milwaukee shoulder syndrome. Case Rep Rheumatol. 2014;2014:458708."},{"issue":"1","key":"4217_CR14","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1186\/s12891-019-2519-y","volume":"20","author":"P Towiwat","year":"2019","unstructured":"Towiwat P, Chhana A, Dalbeth N. The anatomical pathology of gout: a systematic literature review. BMC Musculoskelet Disord. 2019;20(1):140.","journal-title":"BMC Musculoskelet Disord"}],"container-title":["BMC Musculoskeletal Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12891-021-04217-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12891-021-04217-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12891-021-04217-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T14:08:50Z","timestamp":1618236530000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-021-04217-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,12]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["4217"],"URL":"https:\/\/doi.org\/10.1186\/s12891-021-04217-5","relation":{},"ISSN":["1471-2474"],"issn-type":[{"value":"1471-2474","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,12]]},"assertion":[{"value":"18 August 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 April 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Ethics Committee of Clinical Investigation in the Inner Mongolia People\u2019s Hospital.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"A written informed consent form for participation in the case was obtained from the patient. he is aware of this case report and the possibility of it being published.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"We have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"343"}}