{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T22:07:26Z","timestamp":1772662046943,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82161138022"],"award-info":[{"award-number":["82161138022"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Pujiang Young Rheumatologists Training Program","award":["SPROG2106"],"award-info":[{"award-number":["SPROG2106"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Musculoskelet Disord"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Systemic sclerosis (SSc) is an incurable autoimmune disease characterized by progressive skin fibrosis and organ failure. Tenosynovitis is a common musculoskeletal manifestation, but tendon rupture has seldom reported in SSc.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We present a rare case of a 49-year-old female with SSc who has suffered from bilateral tendon rupture of the fourth and fifth digits with positive antinuclear antibody (ANA) and anti-centromere B antibody, but negative rheumatoid factor in serum. In the extensor tendons of the patient\u2019s hands, inflammation, edema, hypertrophy and tendon interruption were detected with ultrasound and magnetic resonance imaging(MRI). Tendon transfer repair surgery was performed and 10\u00a0mg\/week methotrexate was then used in this patient. Her hand function was improved well with methotrexate and rehabilitation treatment postoperatively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Early detection of tenosynovitis is necessary to prevent tendon rupture in SSc patients. Ultrasound and Magnetic Resonance Imaging appear to be useful examinations for evaluating tendon pathology for early detection.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12891-022-05967-6","type":"journal-article","created":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T11:11:23Z","timestamp":1669201883000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Spontaneous tendon rupture in a patient with systemic sclerosis: a case report"],"prefix":"10.1186","volume":"23","author":[{"given":"Cong","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixing","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yundong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoqiang","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiguo","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hejian","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3580-1997","authenticated-orcid":false,"given":"Xiaoxia","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,22]]},"reference":[{"key":"5967_CR1","doi-asserted-by":"publisher","first-page":"15002","DOI":"10.1038\/nrdp.2015.2","volume":"1","author":"Y Allanore","year":"2015","unstructured":"Allanore Y, Simms R, Distler O, Trojanowska M, Pope J, Denton CP, et al. Systemic sclerosis. Nat Rev Dis Primers. 2015;1:15002. https:\/\/doi.org\/10.1038\/nrdp.2015.2.","journal-title":"Nat Rev Dis Primers"},{"issue":"10103","key":"5967_CR2","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1016\/s0140-6736(17)30933-9","volume":"390","author":"CP Denton","year":"2017","unstructured":"Denton CP, Khanna D. Systemic sclerosis. Lancet (London, England). 2017;390(10103):1685\u201399. https:\/\/doi.org\/10.1016\/s0140-6736(17)30933-9 PubMed PMID: 28413064 Epub 2017\/04\/18.","journal-title":"Lancet (London, England)."},{"issue":"10 Pt 2","key":"5967_CR3","doi-asserted-by":"publisher","first-page":"e315","DOI":"10.1016\/j.lpm.2014.03.027","volume":"43","author":"V Lorand","year":"2014","unstructured":"Lorand V, Czirjak L, Minier T. Musculoskeletal involvement in systemic sclerosis. Presse Med. 2014;43(10 Pt 2):e315-28. https:\/\/doi.org\/10.1016\/j.lpm.2014.03.027 PubMed PMID: 25179276 Epub 2014\/09\/03.","journal-title":"Presse Med"},{"issue":"7","key":"5967_CR4","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.3899\/jrheum.091165","volume":"37","author":"J Avouac","year":"2010","unstructured":"Avouac J, Walker U, Tyndall A, Kahan A, Matucci-Cerinic M, Allanore Y, et al. Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database. J Rheumatol. 2010;37(7):1488\u2013501. https:\/\/doi.org\/10.3899\/jrheum.091165 PubMed PMID: 20551097 Epub 2010\/06\/17.","journal-title":"J Rheumatol"},{"issue":"3","key":"5967_CR5","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1007\/s40674-016-0052-9","volume":"2","author":"A Young","year":"2016","unstructured":"Young A, Namas R, Dodge C, Khanna D. Hand Impairment in Systemic Sclerosis: Various Manifestations and Currently Available Treatment. Curr Treatm Opt Rheumatol. 2016;2(3):252\u201369. https:\/\/doi.org\/10.1007\/s40674-016-0052-9 PubMed PMID: 28018840; PubMed Central PMCID: PMCPMC5176259 Epub 2016\/12\/27.","journal-title":"Curr Treatm Opt Rheumatol"},{"issue":"11","key":"5967_CR6","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1136\/annrheumdis-2013-203596","volume":"73","author":"GA Bruyn","year":"2014","unstructured":"Bruyn GA, Hanova P, Iagnocco A, d\u2019Agostino MA, Moller I, Terslev L, et al. Ultrasound definition of tendon damage in patients with rheumatoid arthritis. Results of a OMERACT consensus-based ultrasound score focussing on the diagnostic reliability. Ann Rheum Dis. 2014;73(11):1929\u201334. https:\/\/doi.org\/10.1136\/annrheumdis-2013-203596 PubMed PMID: 23940212 Epub 2013\/08\/14.","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"5967_CR7","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s40674-016-0039-6","volume":"2","author":"P Clements","year":"2016","unstructured":"Clements P. Management of Musculoskeletal Involvement in Systemic Sclerosis. Curr Treatm Opt Rheumatol. 2016;2(1):61\u20138. https:\/\/doi.org\/10.1007\/s40674-016-0039-6 PubMed PMID: 27597931; PubMed Central PMCID: PMCPMC5010020 Epub 2016\/09\/07.","journal-title":"Curr Treatm Opt Rheumatol"},{"issue":"3","key":"5967_CR8","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1093\/rheumatology\/kes307","volume":"52","author":"MS Stoenoiu","year":"2013","unstructured":"Stoenoiu MS, Houssiau FA, Lecouvet FE. Tendon friction rubs in systemic sclerosis: a possible explanation\u2013an ultrasound and magnetic resonance imaging study. 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The patient and the healthy control involved in this research provided fully informed written consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent for publication of this Case Report was obtained from the patient. Competing interests. The authors declare there are no competing financial interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors certify that they have no competing interests to declare that are relevant to the content of this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1001"}}