{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T22:18:48Z","timestamp":1782598728313,"version":"3.54.5"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:00:00Z","timestamp":1714608000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:00:00Z","timestamp":1714608000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Musculoskelet Disord"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Benign Joint Hypermobility Syndrome (BJHS) is a most common hereditary connective tissue disorders in children and adolescents. This study aimed to investigate the prevalence and subtypes of headache in children with BJHS.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This observational-analytical study was conducted in a case-control setting on school children aged 7 to 16 years in 2021\u20132023 in Isfahan, Iran. Students were examined for BJHS using Beighton criteria by a pediatric rheumatologist. Headache disorder was diagnosed according to the Child Headache-Attributed Restriction, Disability, and Social Handicap and Impaired Participation (HARDSHIP) questionnaires for child and adolescent and International Classification of Headache Disorders (ICHD-III).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 4,832 student (mean age 10.3\u2009\u00b1\u20093.1 years), 798 patients with BJHS and 912 healthy children were evaluated. The probability of headache in children aged 7\u201311 with hypermobility was 3.7 times lower than in children aged 12\u201316 with hypermobility (<jats:italic>P<\/jats:italic>\u2009=\u20090.001). The occurrence of headache in children with BJHS was more than the control group (<jats:italic>P<\/jats:italic>\u2009=\u20090.001), and the probability of headache in children with BJHS was 3.7 times higher than in healthy children (<jats:italic>P<\/jats:italic>\u2009=\u20090.001). Migraine was the most common headache type reported of total cases. The probability of migraine in children with BJHS was 4.5 times higher than healthy children ( <jats:italic>P<\/jats:italic>\u2009=\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This study showed a significant correlation between BJHS and headache (especially migraine) in children and adolescents.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12891-024-07473-3","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T02:01:52Z","timestamp":1714615312000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Correlation between benign joint hypermobility syndrome and headache in children and adolescents"],"prefix":"10.1186","volume":"25","author":[{"given":"Mohsen","family":"Jari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sogol","family":"Alesaeidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,2]]},"reference":[{"key":"7473_CR1","doi-asserted-by":"publisher","unstructured":"Russek LN, Stott P, Simmonds J. 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