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Due to its multi-factorial facets, the application of multimodal interventions is recommended. MultiMove is a multimodal intervention designed for CLBP patients, which combines motor-cognitive and dancing exercises. This study aimed to assess the effects of an additional MultiMove intervention to a standard inpatient rehabilitation on clinical and functional outcomes in CLBP patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>For this prospective, two-arm, controlled pilot trial, 27 CLBP patients (17 females, 10 males) undergoing a 3-week inpatient rehabilitation, in a rehabilitation clinic in Germany, were recruited. The intervention group (IG, <jats:italic>n<\/jats:italic>\u2009=\u200915, 61.6\u2009\u00b1\u20091.8 years) received a daily MultiMove session in addition to the standard rehabilitation, while the control group (CG, <jats:italic>n<\/jats:italic>\u2009=\u200912, 63.8\u2009\u00b1\u20092.2 years) followed the standard rehabilitation. Physical (Timed Up and Go (TUG) [primary outcome], Five-Repetition Sit-to-Stand (FRSTS), and Six-Minute Walk Test (6MWT), trunk range of motion, single and dual task walking)), clinical (acute\/chronic pain intensity, Oswestry Disability Index, EQ-5D-5\u00a0L), cognitive (Stroop Color Word Test, Trail Making Test), and psychosocial outcomes (Tampa Scale of Kinesiophobia, Beck Depression Inventory-II, Coping Strategies Questionnaire) were assessed during the first (pre-test) and last day (post-test) of the inpatient rehabilitation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The statistical analyses revealed improvements in trunk range of motion (sagittal plane: <jats:italic>p<\/jats:italic>\u2009=\u20090.018, <jats:italic>d<\/jats:italic>\u2009=\u20091.00; transversal plane: <jats:italic>p<\/jats:italic>\u2009=\u20090.006, <jats:italic>d<\/jats:italic>\u2009=\u20091.18) and 6MWT performance (<jats:italic>p<\/jats:italic>\u2009=\u20090.003, <jats:italic>d<\/jats:italic>\u2009=\u20091.30) in the IG compared to the CG. Moreover, lower dual task costs for a gait variability measure (<jats:italic>p<\/jats:italic>\u2009=\u20090.034, <jats:italic>d<\/jats:italic>\u2009=\u20090.97) as well as reduced chronic pain intensity (<jats:italic>p<\/jats:italic>\u2009=\u20090.004, <jats:italic>d<\/jats:italic>\u2009=\u20091.33), kinesiophobia (<jats:italic>p<\/jats:italic>\u2009=\u20090.035, <jats:italic>d<\/jats:italic>\u2009=\u20091.15), and depression (<jats:italic>p<\/jats:italic>\u2009=\u20090.034, <jats:italic>d<\/jats:italic>\u2009=\u20091.08) were found in favour of the IG.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Data indicate that the multimodal intervention MultiMove improved clinical and functional outcomes in CLBP patients during inpatient rehabilitation. Therefore, conducting a randomized controlled trial with a large sample size is recommended to verify and extent these results.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Trial registration<\/jats:title>\n            <jats:p>MultiMove project (German Clinical Trial Register, ID: DRKS00021696 \/ 10.07.2020, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/drks.de\/drks_web\/navigate.do?navigationId=trial.HTML26TRIAL_ID=DRKS00021696\" ext-link-type=\"uri\">https:\/\/drks.de\/drks_web\/navigate.do?navigationId=trial.HTML26TRIAL_ID=DRKS00021696<\/jats:ext-link>) and was carried out in the rehabilitation clinic Bad Salzelmen (Sch\u00f6nebeck, Germany).<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s12891-025-08494-2","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T06:20:17Z","timestamp":1744784417000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of an additional multimodal intervention (MultiMove) during inpatient rehabilitation on clinical and functional outcomes in patients with chronic low back pain\u2013 a pilot trial"],"prefix":"10.1186","volume":"26","author":[{"given":"Toan","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Behrens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim-Charline","family":"Broscheid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Bielitzki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Rohkohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivonne","family":"Rudolph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Meiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Franke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"Schega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"key":"8494_CR1","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jot.2021.07.005","volume":"32","author":"S Chen","year":"2022","unstructured":"Chen S, Chen M, Wu X, Lin S, Tao C, Cao H, et al. 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