{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:52:48Z","timestamp":1761897168554,"version":"3.37.3"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Surg"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>Ectopic mediastinal parathyroid tumor (EMPT) is a rare cause of primary hyperparathyroidism (PHPT); it is difficult to resect using the cervical approach. We describe a case of using video-assisted thoracic surgery (VATS) for EMPT resection.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Case presentation<\/jats:title>\n<jats:p>A 67-year-old woman with a history of postoperative thyroid cancer had no symptoms. She was diagnosed with PHPT and underwent thyroid cancer surgery. She had serum calcium and intact parathyroid hormone (PTH) levels of 11.1\u2009mg\/dL and 206\u2009pg\/mL, respectively. Chest computed tomography showed a 10-mm nodule in the anterior mediastinum. Technetium-99\u2009m methoxyisobutyl isonitrile scintigraphy showed an abnormal uptake lesion in the anterior mediastinum. She was diagnosed with PHPT caused by EMPT and underwent VATS. The pathological examination confirmed parathyroid adenoma. Her serum calcium and intact PTH levels were normal from 15\u2009min after tumor resection. She has had no recurrence of EMPT.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The VATS approach was effective for the resection of EMPT.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12893-019-0641-2","type":"journal-article","created":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T14:03:10Z","timestamp":1573740190000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Thoracoscopic surgical case of an ectopic mediastinal parathyroid adenoma detected by chance: a case report"],"prefix":"10.1186","volume":"19","author":[{"given":"Shota","family":"Mitsuboshi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroe","family":"Aoshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamami","family":"Isaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takako","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Onizuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6428-8993","authenticated-orcid":false,"given":"Masato","family":"Kanzaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,11,14]]},"reference":[{"key":"641_CR1","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1055\/s-0032-1327628","volume":"120","author":"G Noussios","year":"2012","unstructured":"Noussios G, Anagnostis P, Natsis K. Ectopic parathyroid glands and their anatomical, clinical, and surgical implications. Exp Clin Endoclinol Diabetes. 2012;120:604\u201310.","journal-title":"Exp Clin Endoclinol Diabetes"},{"key":"641_CR2","first-page":"193","volume":"29","author":"A Miya","year":"2012","unstructured":"Miya A. Diagnosis and surgical treatment of hyperparathyroidism arising from ectopic parathyroid glands. Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery. 2012;29:193\u20137.","journal-title":"Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery"},{"key":"641_CR3","doi-asserted-by":"publisher","first-page":"3561","DOI":"10.1210\/jc.2014-1413","volume":"99","author":"JP Bilezikian","year":"2014","unstructured":"Bilezikian JP, Brandi ML, Eastell R, Silverberg SJ, Udelaman R, Marcocci C, et al. Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the fourth international workshop. J Clin Endocrinol Metab. 2014;99:3561\u20139.","journal-title":"J Clin Endocrinol Metab"},{"key":"641_CR4","doi-asserted-by":"publisher","first-page":"1750","DOI":"10.1016\/j.athoracsur.2010.02.076","volume":"89","author":"D Sagan","year":"2010","unstructured":"Sagan D, Gozadziuk K. Surgical treatment of mediastinal parathyroid adenoma: rationale for intraoperative parathyroid hormone monitoring. Ann Thorac Surg. 2010;89:1750\u20135.","journal-title":"Ann Thorac Surg"},{"key":"641_CR5","first-page":"1","volume":"4","author":"M Ishikawa","year":"2017","unstructured":"Ishikawa M, Sumitomo S, Imamura N, Nishida T, Mineura K. A rare case of mediastinal functioning parathyroid adenoma removed successfully with thoracoscopy. J Surg Case Rep. 2017;4:1\u20133.","journal-title":"J Surg Case Rep"},{"key":"641_CR6","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1007\/s11748-011-0796-y","volume":"60","author":"Y Adachi","year":"2012","unstructured":"Adachi Y, Nakamura H, Taniguchi Y, Miwa K, Fujioka S, Haruki T. Thoracoscopic resection with intraoperative use of methylene blue to localize mediastinal parathyroid adenoma. Gen Thorac Cardiovasc Surg. 2012;60:168\u201370.","journal-title":"Gen Thorac Cardiovasc Surg"}],"container-title":["BMC Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12893-019-0641-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12893-019-0641-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12893-019-0641-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T00:17:02Z","timestamp":1605226622000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcsurg.biomedcentral.com\/articles\/10.1186\/s12893-019-0641-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,14]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["641"],"URL":"https:\/\/doi.org\/10.1186\/s12893-019-0641-2","relation":{},"ISSN":["1471-2482"],"issn-type":[{"type":"electronic","value":"1471-2482"}],"subject":[],"published":{"date-parts":[[2019,11,14]]},"assertion":[{"value":"25 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The patient consented to publication of this case. A copy of written consent is available for review by the Editor of this journal.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"171"}}