{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:37:41Z","timestamp":1782603461737,"version":"3.54.5"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T00:00:00Z","timestamp":1619395200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T00:00:00Z","timestamp":1619395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Surg"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Adrenal hemangioma is a rare benign adrenal tumor that is usually misdiagnosed preoperatively. We here present a case of adrenal cavernous hemangioma that was successfully treated with retroperitoneal laparoscopic adrenalectomy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 67-year-old man with dull right back pain attended our clinic for examination of a mass on the right adrenal gland for 1\u00a0week. Pheochromocytoma was considered according\u00a0to\u00a0the\u00a0preoperative computed tomography\u00a0angiography\u2009+\u2009computed\u00a0tomography\u00a0urography findings and was\u00a0subsequently corrected\u00a0to adrenal gland hemangioma according\u00a0to\u00a0postoperative\u00a0pathological\u00a0findings. The patient showed no recurrence of adrenal hemangioma during the 1-year follow-up period after surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Adrenal gland hemangioma is rare with a high rate of misdiagnosis, and it should be considered in imaging findings of adrenal tumors with typical hemangioma. Surgery is an effective treatment method.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12893-021-01195-2","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T10:06:17Z","timestamp":1619431577000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Adrenal cavernous hemangioma misdiagnosed as pheochromocytoma: a case report"],"prefix":"10.1186","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6374-4707","authenticated-orcid":false,"given":"Ting","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Xiao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,26]]},"reference":[{"key":"1195_CR1","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/S0022-5347(17)67320-8","volume":"74","author":"CC Johnson","year":"1955","unstructured":"Johnson CC, Jeppesen FB. Hemangioma of the adrenal. J Urol. 1955;74:573\u20137.","journal-title":"J Urol."},{"key":"1195_CR2","first-page":"8463890","volume":"2019","author":"JA Degheili","year":"2019","unstructured":"Degheili JA, Abou HNF, El-Moussawi M, et al. Adrenal cavernous hemangioma: a rarely perceived pathology-case illustration and review of literature. Case Rep Pathol. 2019;2019:8463890.","journal-title":"Case Rep Pathol"},{"key":"1195_CR3","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1007\/s00595-012-0203-z","volume":"42","author":"M Oishi","year":"2012","unstructured":"Oishi M, Ueda S, Honjo S, et al. Adrenal cavernous hemangioma with subclinical Cushing\u2019s syndrome: report of a case [J]. Surg Today. 2012;42:973\u20137.","journal-title":"Surg Today"},{"key":"1195_CR4","first-page":"693","volume":"84","author":"L Lorenzon","year":"2013","unstructured":"Lorenzon L, Ziparo V, Caterino S, et al. Bilateral cavernous hemangiomas of the adrenal glands presentation and management of an unusual incidental finding. Ann Ital Chir. 2013;84:693\u20137.","journal-title":"Ann Ital Chir"},{"key":"1195_CR5","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1016\/S0022-5347(01)66473-5","volume":"155","author":"M Stumvoll","year":"1996","unstructured":"Stumvoll M, Fritsche A, Wehrmann M, Dammann F, Becker HD, Eggstein M. A functioning adrenocortical hemangioma. J Urol. 1996;155:638.","journal-title":"J Urol"},{"key":"1195_CR6","first-page":"78","volume":"48","author":"L Thomas","year":"2005","unstructured":"Thomas L, Forbes MD. Retroperitoneal hemorrhage secondary to a ruptured cavernous hemangioma. Can J Surg. 2005;48:78\u20139.","journal-title":"Can J Surg"},{"key":"1195_CR7","first-page":"122","volume":"6","author":"P Piotr","year":"2010","unstructured":"Piotr P, Iwona A, Katarzyna HD, et al. Spontaneous rupture of adrenal haemangioma mimicking abdominal aortic aneurysm rupture. Arch Med Sci. 2010;6:122\u20135.","journal-title":"Arch Med Sci"},{"key":"1195_CR8","first-page":"1","volume":"1","author":"S Yuan","year":"2020","unstructured":"Yuan S, He T, Yang L, et al. Basal Takotsubo syndrome induced by pheochromocytoma rupture. Cardiovasc J Afr. 2020;1:1\u20134.","journal-title":"Cardiovasc J Afr"},{"issue":"1","key":"1195_CR9","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1186\/s12894-019-0554-5","volume":"19","author":"U Maestroni","year":"2019","unstructured":"Maestroni U, Ziglioli F, Baciarello M, et al. Multidisciplinary management of a large pheochromocytoma presenting with cardiogenic shock: a case report. BMC Urol. 2019;19(1):118.","journal-title":"BMC Urol"},{"key":"1195_CR10","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.eucr.2015.03.009","volume":"3","author":"C Pang","year":"2015","unstructured":"Pang C, Wu P, Zhu G. A rare cavernous hemangioma of the adrenal gland. Urol Case Rep. 2015;3:120\u20132.","journal-title":"Urol Case Rep"},{"issue":"5","key":"1195_CR11","doi-asserted-by":"publisher","first-page":"523","DOI":"10.7863\/jum.2003.22.5.523","volume":"22","author":"HX Xu","year":"2003","unstructured":"Xu HX, Liu GJ. Huge cavernous hemangioma of the adrenal gland: sonographic, computed tomographic, and magnetic resonance imaging findings. J Ultrasound Med. 2003;22(5):523\u20136.","journal-title":"J Ultrasound Med"},{"key":"1195_CR12","first-page":"51","volume":"20","author":"T Yamada","year":"2002","unstructured":"Yamada T, Ishibashi T, Saito H, et al. Two cases of adrenal hemangioma: CT and MRI findings with pathological correlations. Radiat Med. 2002;20:51\u20136.","journal-title":"Radiat Med"},{"key":"1195_CR13","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1111\/j.1440-1673.2004.01268.x","volume":"48","author":"L Pailin","year":"2004","unstructured":"Pailin L, Malai M, Pannee V, et al. Imaging features of unusual adrenal masses. Australas Radiol. 2004;48:107\u201313.","journal-title":"Australas Radiol"},{"issue":"3","key":"1195_CR14","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1148\/rg.343130127","volume":"34","author":"GE Lattin","year":"2014","unstructured":"Lattin GE, Sturgill ED, Tujo CA, et al. From the radiologic pathology archives: Adrenal tumors and tumor-like conditions in the adult: radiologic-pathologic correlation. Radiographics. 2014;34(3):805\u201329.","journal-title":"Radiographics."},{"issue":"1","key":"1195_CR15","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/s40792-019-0611-z","volume":"5","author":"A Tsujimoto","year":"2019","unstructured":"Tsujimoto A, Ueda T, Kuge H, et al. Long-term survival after ad- renal metastasectomy from colorectal cancer: a report of two cases. Surg Case Rep. 2019;5(1):61.","journal-title":"Surg Case Rep"},{"issue":"2","key":"1195_CR16","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S0720-048X(01)00443-0","volume":"41","author":"S H\u00f6nigschnabl","year":"2002","unstructured":"H\u00f6nigschnabl S, Gallo S, Niederle B, et al. How accurate is MR imaging in characterisation of adrenal masses: update of a long-term study. Eur J Radiol. 2002;41(2):113\u201322.","journal-title":"Eur J Radiol"},{"issue":"3","key":"1195_CR17","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1148\/radiol.2453061854","volume":"245","author":"JF Faria","year":"2007","unstructured":"Faria JF, Goldman SM, Szejnfeld J, et al. Adrenal masses: characterization with in vivo proton MR spectroscopy\u2013initial experience. Radiology. 2007;245(3):788\u201397.","journal-title":"Radiology"},{"issue":"4","key":"1195_CR18","doi-asserted-by":"publisher","first-page":"315","DOI":"10.7326\/0003-4819-134-4-200102200-00016","volume":"134","author":"K Pacak","year":"2001","unstructured":"Pacak K, Linehan WM, Eisenhofer G, et al. Recent advances in genetics, diagnosis, localization, and treatment of pheochromocytoma. Ann Intern Med. 2001;134(4):315\u201329.","journal-title":"Ann Intern Med"},{"key":"1195_CR19","doi-asserted-by":"crossref","unstructured":"Chen H, Sippel RS, ODorisio MS, et al; North American Neuroendocrine Tumor Society (NANETS). The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer. Pancreas. 2010;39(6):775\u201383.","DOI":"10.1097\/MPA.0b013e3181ebb4f0"},{"issue":"1","key":"1195_CR20","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1677\/erc.1.01130","volume":"14","author":"R Lib\u00e8","year":"2007","unstructured":"Lib\u00e8 R, Fratticci A, Bertherat J. Adrenocortical cancer: pathophysiology and clinical management. Endocr Relat Cancer. 2007;14(1):13\u201328.","journal-title":"Endocr Relat Cancer"},{"issue":"4","key":"1195_CR21","doi-asserted-by":"publisher","first-page":"421","DOI":"10.4103\/0256-4947.76411","volume":"31","author":"SA Khalid","year":"2011","unstructured":"Khalid SA, Bokhari SA, Alkeraithi M. Adrenal hemangioma in a 19-year-old female. Ann Saudi Med. 2011;31(4):421\u20133.","journal-title":"Ann Saudi Med."},{"key":"1195_CR22","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.ijscr.2015.09.040","volume":"16","author":"A Agrusa","year":"2015","unstructured":"Agrusa A, Romano G, Salamone G, et al. Large cavernous hemangioma of the adrenal gland: laparoscopic treatment. Report of a case. Int J Surg Case Rep. 2015;16:150\u20133.","journal-title":"Int J Surg Case Rep."},{"issue":"3","key":"1195_CR23","first-page":"180","volume":"19","author":"C Wang","year":"2014","unstructured":"Wang C, Feng L, Wang L, et al. The left giant adrenal hemangioma(a report of one case and literature review). J Mod Urol. 2014;19(3):180\u20132.","journal-title":"J Mod Urol."},{"issue":"5","key":"1195_CR24","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1007\/s00423-016-1533-x","volume":"402","author":"OM Vrielink","year":"2017","unstructured":"Vrielink OM, Wevers KP, Kist JW, et al. Laparoscopic anterior versus endoscopic posterior approach for adrenalectomy: a shift to a new golden standard? Langenbecks Arch Surg. 2017;402(5):767\u201373.","journal-title":"Langenbecks Arch Surg"},{"key":"1195_CR25","first-page":"385","volume":"32","author":"A Agrusa","year":"2016","unstructured":"Agrusa A, Romano G, Dominguez LJ, et al. Adrenal cavernous hemangioma: which correct decision making process? Acta Medica Mediterranea. 2016;32:385\u20139.","journal-title":"Acta Medica Mediterranea"}],"container-title":["BMC Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12893-021-01195-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12893-021-01195-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12893-021-01195-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T10:15:42Z","timestamp":1619432142000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcsurg.biomedcentral.com\/articles\/10.1186\/s12893-021-01195-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,26]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1195"],"URL":"https:\/\/doi.org\/10.1186\/s12893-021-01195-2","relation":{},"ISSN":["1471-2482"],"issn-type":[{"value":"1471-2482","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,26]]},"assertion":[{"value":"13 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This case report has been performed in accordance with the Declaration of Helsinki. The patient gave informed consent, and patient anonymity was preserved.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors obtained the written informed consent for publication from this patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"No conflict of interest exits in the submission of this manuscript, and manuscript is approved by all authors for publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"210"}}